dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0005679
Uniprot Accession P12887; UNG_YEAST; D6VZF3; E9P912;
Genbank Protein ID NP_013691.1;
Genbank Nucleotide ID NM_001182379.1;
Protein Name Uracil-DNA glycosylase
Protein Synonyms/Alias
Gene Name UNG1
Gene Synonyms/Alias YML021C;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)		 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. Not involved in strand-directed mismatch repair.
Phosphorylation Sites
 dbPAF PTMs: 3
PositionPeptidesSourceReferences ( PMIDs )
93NLSSNLRTLLSLELEcurated22817900
105ELETIDDSWFPHLMDcurated22817900
324KMINDWLYNTRGEKMcurated23825934
Sequence
(Fasta)		MWCMRRLPTN SVMTVARKRK QTTIEDFFGT KKSTNEAPNK KGKSGATFMT ITNGAAIKTE 60
TKAVAKEANT DKYPANSNAK DVYSKNLSSN LRTLLSLELE TIDDSWFPHL MDEFKKPYFV 120
KLKQFVTKEQ ADHTVFPPAK DIYSWTRLTP FNKVKVVIIG QDPYHNFNQA HGLAFSVKPP 180
TPAPPSLKNI YKELKQEYPD FVEDNKVGDL THWASQGVLL LNTSLTVRAH NANSHSKHGW 240
ETFTKRVVQL LIQDREADGK SLVFLLWGNN AIKLVESLLG STSVGSGSKY PNIMVMKSVH 300
PSPLSASRGF FGTNHFKMIN DWLYNTRGEK MIDWSVVPGT SLREVQEANA RLESESKDP 360
Keyword

KW-0181--Complete proteome
KW-0227--DNA damage
KW-0234--DNA repair
KW-0326--Glycosidase
KW-0378--Hydrolase
KW-0496--Mitochondrion
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0809--Transit peptide
Interpro

IPR018085--Ura-DNA_Glyclase_AS
IPR002043--Ura_DNA_glycsylse
IPR005122--Uracil-DNA_glycosylase-like
PROSITE

PS00130--U_DNA_GLYCOSYLASE
Pfam

PF03167--UDG
Gene Ontology

GO:0005739--C:mitochondrion
GO:0005634--C:nucleus
GO:0004844--F:uracil DNA N-glycosylase activity
GO:0006284--P:base-excision repair
GO:0006281--P:DNA repair