| Tag |
Content |
| dbPAF ID |
dbPAF-0005676 |
| Uniprot Accession |
P12881; PSA1_DROME; Q8SZ22; Q9VL23;
|
| Genbank Protein ID |
NP_001285798.1; NP_523532.1;
|
| Genbank Nucleotide ID |
NM_001298869.1; NM_078808.4;
|
| Protein Name |
Proteasome subunit alpha type-1 |
| Protein Synonyms/Alias |
PROS-Dm35;Proteasome 35 kDa subunit; |
| Gene Name |
Prosalpha6 |
| Gene Synonyms/Alias |
PROS-35;Pros35;CG4904; |
| Organism |
Drosophila melanogaster(Fruit fly) |
| NCBI Taxa ID |
7227 |
Functional Description
(View all) |
The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.Functional Description
The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. |
Phosphorylation Sites
|
dbPAF PTMs: 1 |
Sequence
(Fasta) | MFRNQYDSDV TVWSPQGRLH QVEYAMEAVK LGTATVGLKN KDYAVLVALC KPTSELSDTQ 60
RKIIPIDDHL GISIAGLTAD ARVLSRYLRS ECLNYKHSYD TTYPVSRLIT NLGNKMQTTT 120
QRYDRRPYGV GLLVAGYDER GPHIYQVTPS ATFFNCKANS IGSRSQSART YLEKNLNKFL 180
DSSKDEIIRH GIRAILGTLP TDEQGKDAGQ YDITVAIVGK DQPFTILSNK DSAKHVAIAK 240
ENDNDTPRND DDDDRPSPPE EPAAGPRDPE VLVATEQRP
Fasta Sequence
>P12881|Prosalpha6|Drosophila melanogaster(Fruit fly)
MFRNQYDSDVTVWSPQGRLHQVEYAMEAVKLGTATVGLKNKDYAVLVALCKPTSELSDTQRKIIPIDDHLGISIAGLTADARVLSRYLRSECLNYKHSYDTTYPVSRLITNLGNKMQTTTQRYDRRPYGVGLLVAGYDERGPHIYQVTPSATFFNCKANSIGSRSQSARTYLEKNLNKFLDSSKDEIIRHGIRAILGTLPTDEQGKDAGQYDITVAIVGKDQPFTILSNKDSAKHVAIAKENDNDTPRNDDDDDRPSPPEEPAAGPRDPEVLVATEQRP
|
| Keyword |
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0903--Direct protein sequencing
KW-0378--Hydrolase
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-0645--Protease
KW-0647--Proteasome
KW-1185--Reference proteome
KW-0888--Threonine protease
|
| Interpro |
IPR029055--Ntn_hydrolases_N
IPR000426--Proteasome_asu_N
IPR023332--Proteasome_suA-type
IPR001353--Proteasome_sua/b
|
| PROSITE |
PS00388--PROTEASOME_ALPHA_1
PS51475--PROTEASOME_ALPHA_2
|
| Pfam |
PF00227--Proteasome
PF10584--Proteasome_A_N
|
| Gene Ontology |
GO:0005737--C:cytoplasm
GO:0005875--C:microtubule associated complex
GO:0005634--C:nucleus
GO:0000502--C:proteasome complex
GO:0005839--C:proteasome core complex
GO:0019773--C:proteasome core complex, alpha-subunit complex
GO:0004175--F:endopeptidase activity
GO:0004298--F:threonine-type endopeptidase activity
GO:0010499--P:proteasomal ubiquitin-independent protein catabolic process
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0007370--P:ventral furrow formation
|
