dbPAF Protein Information
| Tag | Content |
|---|---|
| dbPAF ID | dbPAF-0005633 |
| Uniprot Accession | P12612; TCPA_YEAST; D6VSJ6; |
| Genbank Protein ID | NP_010498.1; |
| Genbank Nucleotide ID | NM_001180520.1; |
| Protein Name | T-complex protein 1 subunit alpha |
| Protein Synonyms/Alias | |
| Gene Name | TCP1 |
| Gene Synonyms/Alias | CCT1;YDR212W;YD8142.13;YD8142B.04; |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast) |
| NCBI Taxa ID | 559292 |
| Functional Description (View all) |
Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin. In yeast may play a role in mitotic spindle formation. |
| Phosphorylation Sites |
dbPAF PTMs: 4 |
| Sequence (Fasta) | MSQLFNNSRS DTLFLGGEKI SGDDIRNQNV LATMAVANVV KSSLGPVGLD KMLVDDIGDF 60 TVTNDGATIL SLLDVQHPAG KILVELAQQQ DREIGDGTTS VVIIASELLK RANELVKNKI 120 HPTTIITGFR VALREAIRFI NEVLSTSVDT LGKETLINIA KTSMSSKIIG ADSDFFSNMV 180 VDALLAVKTQ NSKGEIKYPV KAVNVLKAHG KSATESLLVP GYALNCTVAS QAMPKRIAGG 240 NVKIACLDLN LQKARMAMGV QINIDDPEQL EQIRKREAGI VLERVKKIID AGAQVVLTTK 300 GIDDLCLKEF VEAKIMGVRR CKKEDLRRIA RATGATLVSS MSNLEGEETF ESSYLGLCDE 360 VVQAKFSDDE CILIKGTSKH SSSSIILRGA NDYSLDEMER SLHDSLSVVK RTLESGNVVP 420 GGGCVEAALN IYLDNFATTV GSREQLAIAE FAAALLIIPK TLAVNAAKDS SELVAKLRSY 480 HAASQMAKPE DVKRRSYRNY GLDLIRGKIV DEIHAGVLEP TISKVKSLKS ALEACVAILR 540 IDTMITVDPE PPKEDPHDH |
| Keyword | KW-0002--3D-structure |
| Interpro | IPR012715--Chap_CCT_alpha |
| PROSITE | |
| Pfam | PF00118--Cpn60_TCP1 |
| Gene Ontology | GO:0005832--C:chaperonin-containing T-complex |