| Tag |
Content |
| dbPAF ID |
dbPAF-0005624 |
| Uniprot Accession |
P12385; ERF1_YEAST; D6VQD9;
|
| Genbank Protein ID |
NP_009701.3;
|
| Genbank Nucleotide ID |
NM_001178491.3;
|
| Protein Name |
Eukaryotic peptide chain release factor subunit 1 |
| Protein Synonyms/Alias |
|
| Gene Name |
SUP45 |
| Gene Synonyms/Alias |
SAL4;SUP1;YBR143C;YBR1120; |
| Organism |
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast) |
| NCBI Taxa ID |
559292 |
Functional Description
(View all) |
Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA.Functional Description
Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA. |
Phosphorylation Sites
|
dbPAF PTMs: 6 |
Sequence
(Fasta) | MDNEVEKNIE IWKVKKLVQS LEKARGNGTS MISLVIPPKG QIPLYQKMLT DEYGTASNIK 60
SRVNRLSVLS AITSTQQKLK LYNTLPKNGL VLYCGDIITE DGKEKKVTFD IEPYKPINTS 120
LYLCDNKFHT EVLSELLQAD DKFGFIVMDG QGTLFGSVSG NTRTVLHKFT VDLPKKHGRG 180
GQSALRFARL REEKRHNYVR KVAEVAVQNF ITNDKVNVKG LILAGSADFK TDLAKSELFD 240
PRLACKVISI VDVSYGGENG FNQAIELSAE ALANVKYVQE KKLLEAYFDE ISQDTGKFCY 300
GIDDTLKALD LGAVEKLIVF ENLETIRYTF KDAEDNEVIK FAEPEAKDKS FAIDKATGQE 360
MDVVSEEPLI EWLAANYKNF GATLEFITDK SSEGAQFVTG FGGIGAMLRY KVNFEQLVDE 420
SEDEYYDEDE GSDYDFI
438Fasta Sequence
>P12385|SUP45|Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
MDNEVEKNIEIWKVKKLVQSLEKARGNGTSMISLVIPPKGQIPLYQKMLTDEYGTASNIKSRVNRLSVLSAITSTQQKLKLYNTLPKNGLVLYCGDIITEDGKEKKVTFDIEPYKPINTSLYLCDNKFHTEVLSELLQADDKFGFIVMDGQGTLFGSVSGNTRTVLHKFTVDLPKKHGRGGQSALRFARLREEKRHNYVRKVAEVAVQNFITNDKVNVKGLILAGSADFKTDLAKSELFDPRLACKVISIVDVSYGGENGFNQAIELSAEALANVKYVQEKKLLEAYFDEISQDTGKFCYGIDDTLKALDLGAVEKLIVFENLETIRYTFKDAEDNEVIKFAEPEAKDKSFAIDKATGQEMDVVSEEPLIEWLAANYKNFGATLEFITDKSSEGAQFVTGFGGIGAMLRYKVNFEQLVDESEDEYYDEDEGSDYDFI
|
| Keyword |
KW-0002--3D-structure
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0488--Methylation
KW-0597--Phosphoprotein
KW-0648--Protein biosynthesis
KW-1185--Reference proteome
|
| Interpro |
IPR005140--eRF1_1_Pelota
IPR005141--eRF1_2
IPR005142--eRF1_3
IPR029064--L30e-like
IPR004403--Peptide_chain-rel_eRF1/aRF1
IPR024049--Release_factor_eRF1/aRF1_N
|
| PROSITE |
|
| Pfam |
PF03463--eRF1_1
PF03464--eRF1_2
PF03465--eRF1_3
|
| Gene Ontology |
GO:0010494--C:cytoplasmic stress granule
GO:0005829--C:cytosol
GO:0018444--C:translation release factor complex
GO:0044822--F:poly(A) RNA binding
GO:0043022--F:ribosome binding
GO:0003747--F:translation release factor activity
GO:0016149--F:translation release factor activity, codon specific
GO:0006353--P:DNA-templated transcription, termination
GO:0006449--P:regulation of translational termination
GO:0006415--P:translational termination
|
