dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0005613
Uniprot Accession P12297; SUWA_DROME; Q24543; Q7KW21; Q8MSS2; Q9I7D2; Q9TVZ2;
Genbank Protein ID NP_476756.2; NP_996323.1; NP_996324.1;
Genbank Nucleotide ID NM_057408.6; NM_206600.3; NM_206601.3;
Protein Name Protein suppressor of white apricot
Protein Synonyms/Alias
Gene Name su(w[a])
Gene Synonyms/Alias su(wa);CG3019;
Organism Drosophila melanogaster(Fruit fly)
NCBI Taxa ID 7227
Functional Description
(View all)		 Regulator of pre-mRNA splicing (and, possibly, of other RNA processing events). Regulate its own expression at the level of RNA processing.
Phosphorylation Sites
 dbPAF PTMs: 12
PositionPeptidesSourceReferences ( PMIDs )
364VLQEDESSNPGNSQHPhosphoPep 2.019060867
438VELLKNTSALALAQNdbPTM 3.0;Phospho.ELM 9.0;SysPTM 2.0;UniProt;curated18327897; 16381945; 23193290; 19366988; 22817900
446ALALAQNYSSESEEEdbPTM 3.0;SysPTM 2.0;curated18327897; 16381945; 23193290; 19366988; 22817900
447LALAQNYSSESEEEEdbPTM 3.0;Phospho.ELM 9.0;PHOSIDA;SysPTM 2.0;UniProt;curated18327897; 16381945; 23193290; 21081558; 19366988; 22817900
448ALAQNYSSESEEEEDdbPTM 3.0;Phospho.ELM 9.0;PHOSIDA;SysPTM 2.0;UniProt;curated18327897; 16381945; 23193290; 21081558; 19366988; 22817900
450AQNYSSESEEEEDQVdbPTM 3.0;Phospho.ELM 9.0;PHOSIDA;SysPTM 2.0;UniProt;curated18327897; 16381945; 23193290; 21081558; 19366988; 22817900
649TASPSCSSPQKEQRQdbPTM 3.0;Phospho.ELM 9.0;PhosphoPep 2.0;UniProt18327897; 16381945; 23193290; 19060867
738ESGDSVRSIPITYFGPHOSIDA;curated21081558; 22817900
872RQKSSRLSREPSSNPcurated22817900
912RSKSIRRSRSISILRdbPTM 3.0;Phospho.ELM 9.0;SysPTM 2.0;UniProt;curated18327897; 16381945; 23193290; 19366988; 22817900
914KSIRRSRSISILRNNdbPTM 3.0;Phospho.ELM 9.0;SysPTM 2.0;UniProt;curated18327897; 16381945; 23193290; 19366988; 22817900
916IRRSRSISILRNNRRdbPTM 3.0;Phospho.ELM 9.0;SysPTM 2.0;UniProt;curated18327897; 16381945; 23193290; 19366988; 22817900
Sequence
(Fasta)		MLPYNVRNAG GGSVGGILRR TGQGSGTGST ILGNGNSPGA LGAGKVSSSL ENHRQPPLEL 60
LVFGYACKIF RDDEKAREMD HGKQLIPWMG DVNLKIDRYD VRGALCELAP HEAPPGGYGN 120
RLEYLSAEEQ RAEQLCEEER YLFLYNNEEE LRLRQEEDLK RLQQETSGGC FSQVGFQYDG 180
QSAASTSIGG SSTATSQLSP NSEESELPFV LPYTLMMAPP LDMQLPETMK QHAIIEKTAR 240
FIATQGAQME ILIKAKQANN TQFDFLTQGG HLQPYYRHLL AAIKAAKFPP APQTPLDQQN 300
TDKEAPSADD HSEEVAGGRR NPNQVVITVP TIKYKPSANC AYTQLISKIK GVPLQAVLQE 360
DESSNPGNSQ HSGGTASPAL SCRSEGHNSQ GGEFTPVLLQ YNGSTFTHEE ESSNREQQDD 420
NDVNGGEPPQ VELLKNTSAL ALAQNYSSES EEEEDQVQPE KEEEKKPEPV LTFPVPKDSL 480
RHIIDKTATY VIKNGRQFEE TLRTKSVDRF SFLLPANEYY PYYLYKVTGD VDAASKEEKT 540
RKAAAVAAAL MSKKGLSFGG AAAAVSGSNL DKAPVSFSIR ARDDQCPLQH TLPQEASDEE 600
TSSNAAGVEH VRPGMPDSVQ RAIKQVETQL LARTAGQKGN ITASPSCSSP QKEQRQAEER 660
VKDKLAQIAR EKLNGMISRE KQLQLERKRK ALAFLNQIKG EGAIVGSAVP VVGPNPPESA 720
AGAATADSGD ESGDSVRSIP ITYFGPDDDD EVGEQRPEMR LIGSTQKDEE DDDEEDGGDL 780
EKYNLLNDDS TNTFTSKPVL PPTAAPPPAA VLLSDDDDVQ LVATTSTRSS SSRHLKTHRR 840
SRSRSKNVRS SDSSPSSRES SRRRRQKSSR LSREPSSNPP RKSQHSSTQR KKTPKKRRRS 900
KSRSRSKSIR RSRSISILRN NRRSRSRSPS CRNAEQRRQQ DRRRTPTKKS HKRHKRRRRS 960
SSP 964
Keyword

KW-0025--Alternative splicing
KW-0181--Complete proteome
KW-0507--mRNA processing
KW-0508--mRNA splicing
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
KW-0694--RNA-binding
KW-0804--Transcription
KW-0805--Transcription regulation
Interpro

IPR000061--Surp
IPR019147--SWAP_N_domain
PROSITE

PS50128--SURP
Pfam

PF09750--DRY_EERY
PF01805--Surp
Gene Ontology

GO:0016607--C:nuclear speck
GO:0003723--F:RNA binding
GO:0006376--P:mRNA splice site selection
GO:0006355--P:regulation of transcription, DNA-templated
GO:0006351--P:transcription, DNA-templated