dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0005550
Uniprot Accession P11747; TAF13_YEAST; D6W0I7;
Genbank Protein ID NP_013611.1;
Genbank Nucleotide ID NM_001182458.1;
Protein Name Transcription initiation factor TFIID subunit 13
Protein Synonyms/Alias Function unknown 81 protein;TAFII-19;TAFII19;TBP-associated factor 13;TBP-associated factor 19 kDa;
Gene Name TAF13
Gene Synonyms/Alias FUN81;TAF19;YML098W;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)
Functions as a component of the DNA-binding general transcription factor complex TFIID. Binding of TFIID to a promoter (with or without TATA element) is the initial step in pre-initiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modification (histone acetylation by TAF1), facilitation of DNA opening and initiation of transcription.
Phosphorylation Sites
dbPAF PTMs: 1
PositionPeptidesSourceReferences ( PMIDs )
131DEDEQQVTDDDEEAAdbPTM 3.0;PhosphoGRID 2.0;PHOSIDA;PhosphoPep 2.0;UniProt;curated17563356; 16381945; 23193290; 20702584; 19779198; 21081558;
Sequence
(Fasta)
MSRKLKKTNL FNKDVSSLLY AYGDVPQPLQ ATVQCLDELV SGYLVDVCTN AFHTAQNSQR 60
NKLRLEDFKF ALRKDPIKLG RAEELIATNK LITEAKKQFN ETDNQNSLKR YREEDEEGDE 120
MEEDEDEQQV TDDDEEAAGR NSAKQSTDSK ATKIRKQGPK NLKKTKK 168
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0804--Transcription
KW-0805--Transcription regulation

Interpro

IPR009072--Histone-fold
IPR003195--TFIID-18

PROSITE
Pfam

PF02269--TFIID-18kDa

Gene Ontology

GO:0005669--C:transcription factor TFIID complex
GO:0003677--F:DNA binding
GO:0003712--F:transcription cofactor activity
GO:0006357--P:regulation of transcription from RNA polymerase II promoter
GO:0051123--P:RNA polymerase II transcriptional preinitiation complex assembly
GO:0006366--P:transcription from RNA polymerase II promoter