dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0005548
Uniprot Accession P11745; RNA1_YEAST; D6W061;
Genbank Protein ID NP_013962.1;
Genbank Nucleotide ID NM_001182742.1;
Protein Name Ran GTPase-activating protein 1
Protein Synonyms/Alias Protein involved in RNA production/processing;
Gene Name RNA1
Gene Synonyms/Alias YMR235C;YM9959.17C;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)
GTPase activator for the nuclear Ras-related regulatory protein GSP1 (Ran), converting it to the putatively inactive GDP-bound state.
Phosphorylation Sites
dbPAF PTMs: 3
PositionPeptidesSourceReferences ( PMIDs )
144NIKHLILSNNGMGPFcurated22369663
337GNRLDEDSDALDLLQPhosphoGRID 2.0;curated19779198; 22817900
360DDFEEVDSEDEEGEDdbPTM 3.0;PhosphoGRID 2.0;PHOSIDA;PhosphoPep 2.0;SysPTM 2.0;UniProt;curated17330950; 16381945; 23193290; 21177495; 19823750; 19795423;
Sequence
(Fasta)
MATLHFVPQH EEEQVYSISG KALKLTTSDD IKPYLEELAA LKTCTKLDLS GNTIGTEASE 60
ALAKCIAENT QVRESLVEVN FADLYTSRLV DEVVDSLKFL LPVLLKCPHL EIVNLSDNAF 120
GLRTIELLED YIAHAVNIKH LILSNNGMGP FAGERIGKAL FHLAQNKKAA SKPFLETFIC 180
GRNRLENGSA VYLALGLKSH SEGLKVVKLY QNGIRPKGVA TLIHYGLQYL KNLEILDLQD 240
NTFTKHASLI LAKALPTWKD SLFELNLNDC LLKTAGSDEV FKVFTEVKFP NLHVLKFEYN 300
EMAQETIEVS FLPAMEKGNL PELEKLEING NRLDEDSDAL DLLQSKFDDL EVDDFEEVDS 360
EDEEGEDEED EDEDEKLEEI ETERLEKELL EVQVDDLAER LAETEIK 408
Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0343--GTPase activation
KW-0433--Leucine-rich repeat
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR027038--RanGap

PROSITE
Pfam
Gene Ontology

GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0005096--F:GTPase activator activity
GO:0006348--P:chromatin silencing at telomere
GO:0043547--P:positive regulation of GTPase activity
GO:0006606--P:protein import into nucleus
GO:0000054--P:ribosomal subunit export from nucleus
GO:0006404--P:RNA import into nucleus
GO:0006407--P:rRNA export from nucleus
GO:0006409--P:tRNA export from nucleus