dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0005541
Uniprot Accession P11710; FUS1_YEAST; D6VQY8;
Genbank Protein ID NP_009903.2;
Genbank Nucleotide ID NM_001178672.1;
Protein Name Nuclear fusion protein FUS1
Protein Synonyms/Alias
Gene Name FUS1
Gene Synonyms/Alias YCL027W;YCL27W;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)		 Required for cell fusion. Negatively regulates Sho1p signaling to ensure efficient cell fusion.
Phosphorylation Sites
 dbPAF PTMs: 11
PositionPeptidesSourceReferences ( PMIDs )
160WTSGDNMSSKIQYKIdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.017330950; 16381945; 23193290; 19366988
161TSGDNMSSKIQYKISPhosphoPep 2.019060867
178IIPQHILTPKKTVKNdbPTM 3.0;PhosphoGRID 2.0;PhosphoPep 2.0;SysPTM 2.0;UniProt;curated17330950; 16381945; 23193290; 19060867; 19366988; 22817900
190VKNPYAWSGKNISLDdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;UniProt;curated17330950; 16381945; 23193290; 19366988; 22817900
256SEKWSYESPLSRWFLdbPTM 3.0;PhosphoGRID 2.0;PhosphoPep 2.0;SysPTM 2.0;UniProt;curated17330950; 16381945; 23193290; 19060867; 19366988; 22817900
275YFKDYGLSKTSLKTPdbPTM 3.0;PhosphoGRID 2.0;PhosphoPep 2.0;SysPTM 2.017330950; 16381945; 23193290; 19060867; 19366988
277KDYGLSKTSLKTPTGdbPTM 3.0;PhosphoGRID 2.0;PhosphoPep 2.0;SysPTM 2.017330950; 16381945; 23193290; 19060867; 19366988
281LSKTSLKTPTGAPQLdbPTM 3.0;PhosphoGRID 2.0;PhosphoPep 2.0;SysPTM 2.0;UniProt17330950; 16381945; 23193290; 19060867; 19366988
301LSRISKGYFNESDIMdbPTM 3.0;PhosphoGRID 2.0;PhosphoPep 2.0;SysPTM 2.017330950; 16381945; 23193290; 19060867; 19366988
358LITARPHSVIYGTTAdbPTM 3.0;PhosphoGRID 2.0;PhosphoPep 2.0;SysPTM 2.017330950; 16381945; 23193290; 19060867; 19366988
424RSKPLPLTPNSKYNGdbPTM 3.0;PhosphoGRID 2.0;PhosphoPep 2.0;SysPTM 2.0;UniProt;curated17330950; 16381945; 23193290; 19060867; 19366988; 22817900
Sequence
(Fasta)		MVATIMQTTT TVLTTVAAMS TTLASNYISS QASSSTSVTT VTTIATSIRS TPSNLLFSNV 60
AAQPKSSSAS TIGLSIGLPI GIFCFGLLIL LCYFYLKRNS VSISNPPMSA TIPREEEYCR 120
RTNWFSRLFW QSKCEDQNSY SNRDIEKYND TQWTSGDNMS SKIQYKISKP IIPQHILTPK 180
KTVKNPYAWS GKNISLDPKV NEMEEEKVVD AFLYTKPPNI VHIESSMPSY NDLPSQKTVS 240
SKKTALKTSE KWSYESPLSR WFLRGSTYFK DYGLSKTSLK TPTGAPQLKQ MKMLSRISKG 300
YFNESDIMPD ERSPILEYNN TPLDANDSVN NLGNTTPDSQ ITSYRNNNID LITARPHSVI 360
YGTTAQQTLE TNFNDHHDCN KSTEKHELII PTPSKPLKKR KKRRQSKMYQ HLQHLSRSKP 420
LPLTPNSKYN GEASVQLGKT YTVIQDYEPR LTDEIRISLG EKVKILATHT DGWCLVEKCN 480
TQKGSIHVSV DDKRYLNEDR GIVPGDCLQE YD 513
Keyword

KW-0181--Complete proteome
KW-0325--Glycoprotein
KW-0472--Membrane
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0812--Transmembrane
KW-1133--Transmembrane helix
Interpro

IPR001452--SH3_domain
PROSITE

PS50002--SH3
Pfam

PF00018--SH3_1
Gene Ontology

GO:0005938--C:cell cortex
GO:0005887--C:integral component of plasma membrane
GO:0043332--C:mating projection tip
GO:0032065--P:cortical protein anchoring
GO:0000755--P:cytogamy
GO:0031385--P:regulation of termination of mating projection growth