dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0005540
Uniprot Accession P11709; BIK1_YEAST; D6VQY6;
Genbank Protein ID NP_009901.1;
Genbank Nucleotide ID NM_001178674.1;
Protein Name Nuclear fusion protein BIK1
Protein Synonyms/Alias
Gene Name BIK1
Gene Synonyms/Alias YCL029C;YCL29C;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)		 Required for nuclear fusion, chromosome disjunction, and nuclear segregation during mitosis. Probably required for the formation or stabilization of microtubules during mitosis and for spindle pole body fusion during conjugation.
Phosphorylation Sites
 dbPAF PTMs: 18
PositionPeptidesSourceReferences ( PMIDs )
81ASLIEKASISQTSRRPhosphoGRID 2.0;curated21126336; 19823750; 20377248
83LIEKASISQTSRRTTdbPTM 3.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 19366988; 22817900; 19823750;
85EKASISQTSRRTTMEPhosphoGRID 2.0;curated21177495; 22817900; 19823750; 20377248
86KASISQTSRRTTMEPPhosphoPep 2.0;curated19060867; 19823750; 24961812; 20377248
89ISQTSRRTTMEPLSIdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 19779198; 19366988; 22369663;
90SQTSRRTTMEPLSIPdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 19779198; 19366988; 26040289;
95RTTMEPLSIPKNRSIdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;UniProt;curated18407956; 16381945; 23193290; 19779198; 19366988; 25704821;
101LSIPKNRSIVRLTNQPhosphoGRID 2.0;curated19823750; 19795423; 22817900; 24961812; 20377248
106NRSIVRLTNQFSPMDcurated19823750
110VRLTNQFSPMDDPKSdbPTM 3.0;PhosphoGRID 2.0;PhosphoPep 2.0;SysPTM 2.0;UniProt;curated17330950; 18407956; 16381945; 23193290; 19060867; 19366988;
117SPMDDPKSPTPMRSFdbPTM 3.0;PhosphoGRID 2.0;PhosphoPep 2.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 20702584; 19684113; 19060867;
119MDDPKSPTPMRSFRIPhosphoGRID 2.0;PhosphoPep 2.0;curated19684113; 19060867; 22369663; 22817900; 25315811
131FRITSRHSGNQQSMDPhosphoGRID 2.0;curated20702584; 22817900
163EDRMEVDSILSSDRKcurated22369663; 22817900; 25315811; 19547744
166MEVDSILSSDRKANHcurated22369663
167EVDSILSSDRKANHNdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 19366988; 22369663; 25315811
365TKPQDSSSEEVASLTdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 19366988
370SSSEEVASLTKKLEEdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 19366988; 22369663
Sequence
(Fasta)		MDRYQRKIGC FIQIPNLGRG QLKYVGPVDT KAGMFAGVDL LANIGKNDGS FMGKKYFQTE 60
YPQSGLFIQL QKVASLIEKA SISQTSRRTT MEPLSIPKNR SIVRLTNQFS PMDDPKSPTP 120
MRSFRITSRH SGNQQSMDQE ASDHHQQQEF GYDNREDRME VDSILSSDRK ANHNTTSDWK 180
PDNGHMNDLN SSEVTIELRE AQLTIEKLQR KQLHYKRLLD DQRMVLEEVQ PTFDRYEATI 240
QEREKEIDHL KQQLELERRQ QAKQKQFFDA ENEQLLAVVS QLHEEIKENE ERNLSHNQPT 300
GANEDVELLK KQLEQLRNIE DQFELHKTKW AKEREQLKMH NDSLSKEYQN LSKELFLTKP 360
QDSSSEEVAS LTKKLEEANE KIKQLEQAQA QTAVESLPIF DPPAPVDTTA GRQQWCEHCD 420
TMGHNTAECP HHNPDNQQFF 441
Keyword

KW-0131--Cell cycle
KW-0132--Cell division
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0206--Cytoskeleton
KW-0493--Microtubule
KW-0498--Mitosis
KW-0597--Phosphoprotein
KW-1185--Reference proteome
Interpro

IPR000938--CAP-Gly_domain
PROSITE

PS00845--CAP_GLY_1
PS50245--CAP_GLY_2
Pfam

PF01302--CAP_GLY
Gene Ontology

GO:0005938--C:cell cortex
GO:0000778--C:condensed nuclear chromosome kinetochore
GO:0000776--C:kinetochore
GO:0043332--C:mating projection tip
GO:0035371--C:microtubule plus-end
GO:0005819--C:spindle
GO:0005876--C:spindle microtubule
GO:0005816--C:spindle pole body
GO:0008017--F:microtubule binding
GO:0042803--F:protein homodimerization activity
GO:0051301--P:cell division
GO:0000742--P:karyogamy involved in conjugation with cellular fusion
GO:0007067--P:mitotic nuclear division
GO:0000022--P:mitotic spindle elongation
GO:0031115--P:negative regulation of microtubule polymerization
GO:0000743--P:nuclear migration involved in conjugation with cellular fusion