dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0005510
Uniprot Accession P11484; HSP75_YEAST; D6VRC7; Q05834;
Genbank Protein ID NP_010052.1;
Genbank Nucleotide ID NM_001180289.1;
Protein Name Heat shock protein SSB1
Protein Synonyms/Alias Cold-inducible protein YG101;
Gene Name SSB1
Gene Synonyms/Alias YG101;YDL229W;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)		 May aid in the passage of the nascent polypeptide chain through the ribosome channel into the cytosol. Such an interaction could be crucial for continuous transport of the polypeptide; could serve to prevent the nascent polypeptide from interfering with translation by clogging the ribosome channel.
Phosphorylation Sites
 dbPAF PTMs: 36 (View all)
PositionPeptidesSourceReferences ( PMIDs )
26SCVATYESSVEIIANdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 19366988
27CVATYESSVEIIANEdbPTM 3.0;SysPTM 2.018407956; 16381945; 23193290; 19366988
40NEQGNRVTPSFVAFTPhosphoGRID 2.021126336
47TPSFVAFTPEERLIGdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;UniProt;curated15665377; 18407956; 16381945; 23193290; 19366988; 26040289;
84GRRFDDESVQKDMKTPhosphoGRID 2.0;SysPTM 2.0;curated17287358; 19366988; 26040289; 22817900
115QYLEETKTFSPQEIScurated26040289
167TKDAGAISGLNVLRIPhosphoGRID 2.0;curated19779198; 22817900
192YGLGAGKSEKERHVLPhosphoPep 2.0;curated19060867; 22369663; 24961812
211GGGTFDVSLLHIAGGPhosphoGRID 2.0;SysPTM 2.0;curated17287358; 19366988; 22817900
224GGVYTVKSTSGNTHLPhosphoPep 2.0;curated19060867; 19823750
226VYTVKSTSGNTHLGGPhosphoPep 2.019060867
229VKSTSGNTHLGGQDFPhosphoPep 2.019060867
238LGGQDFDTNLLEHFKPhosphoPep 2.019060867
289QTTVEVDSLFDGEDFdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 17287358; 19366988; 22817900
298FDGEDFESSLTRARFPhosphoGRID 2.0;SysPTM 2.0;curated17287358; 19366988; 22817900
301EDFESSLTRARFEDLPhosphoGRID 2.0;SysPTM 2.0;curated17287358; 19366988; 22817900
315LNAALFKSTLEPVEQcurated25521595
332KDAKISKSQIDEVVLdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 19366988; 24961812
354PKVQKLLSDFFDGKQPhosphoGRID 2.0;curated19779198; 22817900; 26040289
431VPTIKRRTFTTCADNdbPTM 3.0;PhosphoGRID 2.0;PhosphoPep 2.0;SysPTM 2.0;UniProt;curated17330950; 16381945; 23193290; 19779198; 19060867; 19366988;
Sequence
(Fasta)		MAEGVFQGAI GIDLGTTYSC VATYESSVEI IANEQGNRVT PSFVAFTPEE RLIGDAAKNQ 60
AALNPRNTVF DAKRLIGRRF DDESVQKDMK TWPFKVIDVD GNPVIEVQYL EETKTFSPQE 120
ISAMVLTKMK EIAEAKIGKK VEKAVITVPA YFNDAQRQAT KDAGAISGLN VLRIINEPTA 180
AAIAYGLGAG KSEKERHVLI FDLGGGTFDV SLLHIAGGVY TVKSTSGNTH LGGQDFDTNL 240
LEHFKAEFKK KTGLDISDDA RALRRLRTAA ERAKRTLSSV TQTTVEVDSL FDGEDFESSL 300
TRARFEDLNA ALFKSTLEPV EQVLKDAKIS KSQIDEVVLV GGSTRIPKVQ KLLSDFFDGK 360
QLEKSINPDE AVAYGAAVQG AILTGQSTSD ETKDLLLLDV APLSLGVGMQ GDMFGIVVPR 420
NTTVPTIKRR TFTTCADNQT TVQFPVYQGE RVNCKENTLL GEFDLKNIPM MPAGEPVLEA 480
IFEVDANGIL KVTAVEKSTG KSSNITISNA VGRLSSEEIE KMVNQAEEFK AADEAFAKKH 540
EARQRLESYV ASIEQTVTDP VLSSKLKRGS KSKIEAALSD ALAALQIEDP SADELRKAEV 600
GLKRVVTKAM SSR 614
Keyword

KW-0002--3D-structure
KW-0007--Acetylation
KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0903--Direct protein sequencing
KW-0547--Nucleotide-binding
KW-0597--Phosphoprotein
KW-0648--Protein biosynthesis
KW-1185--Reference proteome
KW-0346--Stress response
Interpro

IPR018181--Heat_shock_70_CS
IPR029048--HSP70_C
IPR029047--HSP70_peptide-bd
IPR013126--Hsp_70_fam
PROSITE

PS00297--HSP70_1
PS00329--HSP70_2
PS01036--HSP70_3
Pfam

PF00012--HSP70
Gene Ontology

GO:0005737--C:cytoplasm
GO:0005844--C:polysome
GO:0005524--F:ATP binding
GO:0016887--F:ATPase activity
GO:0005516--F:calmodulin binding
GO:0051082--F:unfolded protein binding
GO:0051083--P:'de novo' cotranslational protein folding
GO:0042149--P:cellular response to glucose starvation
GO:0002181--P:cytoplasmic translation
GO:0006450--P:regulation of translational fidelity
GO:0000054--P:ribosomal subunit export from nucleus
GO:0006364--P:rRNA processing
GO:0006452--P:translational frameshifting
GO:0006415--P:translational termination