dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0005499
Uniprot Accession P11420; DA_DROME; Q9VKX3;
Genbank Protein ID NP_001260340.1; NP_001260341.1; NP_477189.1;
Genbank Nucleotide ID NM_001273411.1; NM_001273412.1; NM_057841.4;
Protein Name Protein daughterless
Protein Synonyms/Alias
Gene Name da
Gene Synonyms/Alias CG5102;
Organism Drosophila melanogaster(Fruit fly)
NCBI Taxa ID 7227
Functional Description
(View all)		 Daughterless/Achaete-scute complex heterodimers act as transcriptional activators of neural cell fates and are involved in sex determination.
Phosphorylation Sites
 dbPAF PTMs: 5
PositionPeptidesSourceReferences ( PMIDs )
43GGGGGYHSPYGSLGVdbPTM 3.0;Phospho.ELM 9.0;SysPTM 2.0;UniProt;curated18327897; 16381945; 23193290; 19366988; 22817900
467LKLDRSASTSLPKQTcurated22817900
533GTKRPRRYCSSADEDPhosphoPep 2.0;curated19060867; 22817900
535KRPRRYCSSADEDDDdbPTM 3.0;Phospho.ELM 9.0;PHOSIDA;PhosphoPep 2.0;SysPTM 2.0;UniProt;curated18327897; 16381945; 23193290; 21081558; 19060867; 19366988;
536RPRRYCSSADEDDDAdbPTM 3.0;Phospho.ELM 9.0;PHOSIDA;PhosphoPep 2.0;SysPTM 2.0;UniProt;curated18327897; 16381945; 23193290; 21081558; 19060867; 19366988;
Sequence
(Fasta)		MATSDDEPMH LYEVFQNCFN KIANKQPTGT VGADRGGGGG YHSPYGSLGV ENGMYPSDFN 60
SMHDTVNGGN NRYANASTVD QYFDSAAAGS GGAWCQPQMS SANSYMGQSA YQNSGPLSGH 120
SIDQQQQQVH QADGLGMGGG GGGGVGADGM HCPVTTGLPP ISSFRPTSGG IGGPGAGQQA 180
PVNVNVNPPA VFNSPQAHNH NHTVQAQHSA LSTAGPLGHH SLNHTPHAHS HTLPLPHALP 240
HGHTLPHPHH SQQNSPAVQS SDAFSGAGAS VKVAGAGNSS AAALRQQMYM PADQSISSFG 300
SNPSTPVNSP PPLTQSVVGG GGEPSVSGGS GWGHSVLNGG PSSSYASEMV PVSSLHTMAS 360
VFQGVRMEER LDDALNVLRN HCEPEMLAGV NQSLASIDNI DALTSFVPNS PSHLGSGGNS 420
GSVSNTSNAA LVHEVLALGA AAAAGTSGQS VGGAGSLASL KLDRSASTSL PKQTKKRKEH 480
TAISNSVPAG VSTTSSLTSL DISDTKPTSS IESSNSGLQQ HSQGKGTKRP RRYCSSADED 540
DDAEPAVKAI REKERRQANN ARERIRIRDI NEALKELGRM CMTHLKSDKP QTKLGILNMA 600
VEVIMTLEQQ VRERNLNPKA ACLKRREEEK AEDGPKLSAQ HHMIPQPQQV GGTPGSSYHS 660
QPAQLVPPSS QTISTMTISL PVNQANNGLP PHLQQQQQQQ SQLGHAQLPQ 711
Keyword

KW-0010--Activator
KW-0181--Complete proteome
KW-0217--Developmental protein
KW-0221--Differentiation
KW-0238--DNA-binding
KW-0524--Neurogenesis
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
KW-0804--Transcription
KW-0805--Transcription regulation
Interpro

IPR011598--bHLH_dom
PROSITE

PS50888--BHLH
Pfam

PF00010--HLH
Gene Ontology

GO:0005634--C:nucleus
GO:0005667--C:transcription factor complex
GO:0003677--F:DNA binding
GO:0046982--F:protein heterodimerization activity
GO:0042803--F:protein homodimerization activity
GO:0043565--F:sequence-specific DNA binding
GO:0003700--F:transcription factor activity, sequence-specific DNA binding
GO:0008134--F:transcription factor binding
GO:0001077--F:transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0006974--P:cellular response to DNA damage stimulus
GO:0008407--P:chaeta morphogenesis
GO:0061382--P:Malpighian tubule tip cell differentiation
GO:0007399--P:nervous system development
GO:0061101--P:neuroendocrine cell differentiation
GO:0022008--P:neurogenesis
GO:0048663--P:neuron fate commitment
GO:0048477--P:oogenesis
GO:0030707--P:ovarian follicle cell development
GO:0007422--P:peripheral nervous system development
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0045893--P:positive regulation of transcription, DNA-templated
GO:0045464--P:R8 cell fate specification
GO:0016330--P:second mitotic wave involved in compound eye morphogenesis
GO:0007423--P:sensory organ development
GO:0007530--P:sex determination
GO:0007541--P:sex determination, primary response to X:A ratio
GO:0035019--P:somatic stem cell population maintenance
GO:0006366--P:transcription from RNA polymerase II promoter