dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0005483
Uniprot Accession P11325; SYLM_YEAST; D6VZ17;
Genbank Protein ID NP_013486.3;
Genbank Nucleotide ID NM_001182271.3;
Protein Name Leucine--tRNA ligase, mitochondrial
Protein Synonyms/Alias Leucyl-tRNA synthetase;LeuRS;
Gene Name NAM2
Gene Synonyms/Alias MSL1;YLR382C;L3502.6;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)
Phosphorylation Sites
 dbPAF PTMs: 1
PositionPeptidesSourceReferences ( PMIDs )
48QDTLNSGSKYILCQFcurated24603354
Sequence
(Fasta)		MLSRPSSRFL STKRGPGPAV KKLIAIGEKW KQKTTRGLPK QDTLNSGSKY ILCQFPYPSG 60
ALHIGHLRVY VISDSLNRFY KQKGYNVIHP MGWDAFGLPA ENAAIERSIN PAIWTRDNIA 120
KMKQQMQSML ANFDWDREIT TCDPEYYKFT QWIFLKLFEN GLAYRKEAEI NWDPVDMTVL 180
ANEQVDAQGR SWRSGAIVEK KQLKQWFLGI TKFAPKLKKH LNQLKDWPSN VKQMQKNWIG 240
ESVGAELVFK VADPKFENLI VFTTRPETLF AVQYVALALD HPIVQKYCEE MPDLKEFIQK 300
SDQLPNDTKE GFQLPNIKAV NPLTKEEVPI FAAPYVVSSY GSAPSAVMGC PGHDNRDFEF 360
WQTNCPGEHI KTCIAPFFDD ASKVTEQERQ RIIDTVPFTS TDGVLTKECG EHSGVLTVVA 420
RKSIMGMLNS EGLSKSVVRY KIRDWLISRQ RYWGTPIPII HCDNCGPVPV PESDLPVKLP 480
ELEGLDTKGN PLSTIDEFVN VACPSCGSPA KRETDTMDTF IDSSWYYFRF LDPKNTSKPF 540
DREIASKNMP VDIYIGGVEH AILHLLYSRF IAKFLGSINA WSDPAGIFEP FKKLVTQGMV 600
QGKTYVDPDS GKFLKPDELT FVNDSPDGNT VIIKSNGKVP VVSYEKMSKS KYNGADPNEC 660
ILRHGPDATR AHILFQSPIA DALNWDESKI VGIERWLQKV LHLTKNILSL EKDLAISKDY 720
KTPTDLNDAE VKFHNDFQRF LKSITESFEV NLSLNTVISD YMKLTNILES ALKKGEVRNE 780
MIVQNLQKLV TVIYPAVPSI SEEAAEMINS QMEWNQYRWP EVERTTESKF KKFQIVVNGR 840
VKFMYTADKN FLKLGRDAVI ETLMNLPEGR MYLMNKKIKK FVMKFNVISF LFHK 895
Keyword

KW-0030--Aminoacyl-tRNA synthetase
KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0903--Direct protein sequencing
KW-0436--Ligase
KW-0496--Mitochondrion
KW-0547--Nucleotide-binding
KW-0648--Protein biosynthesis
KW-1185--Reference proteome
KW-0809--Transit peptide
Interpro

IPR001412--aa-tRNA-synth_I_CS
IPR002300--aa-tRNA-synth_Ia
IPR002302--Leu-tRNA-ligase
IPR025709--Leu_tRNA-synth_edit
IPR015413--Methionyl/Leucyl_tRNA_Synth
IPR014729--Rossmann-like_a/b/a_fold
IPR009080--tRNAsynth_1a_anticodon-bd
IPR009008--Val/Leu/Ile-tRNA-synth_edit
PROSITE

PS00178--AA_TRNA_LIGASE_I
Pfam

PF00133--tRNA-synt_1
PF13603--tRNA-synt_1_2
PF09334--tRNA-synt_1g
Gene Ontology

GO:0005759--C:mitochondrial matrix
GO:0005739--C:mitochondrion
GO:0002161--F:aminoacyl-tRNA editing activity
GO:0005524--F:ATP binding
GO:0004823--F:leucine-tRNA ligase activity
GO:0003729--F:mRNA binding
GO:0000372--P:Group I intron splicing
GO:0006429--P:leucyl-tRNA aminoacylation
GO:0032543--P:mitochondrial translation