dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0005438
Uniprot Accession P11076; ARF1_YEAST; D6VRG1;
Genbank Protein ID NP_010089.1;
Genbank Nucleotide ID NM_001180252.1;
Protein Name ADP-ribosylation factor 1
Protein Synonyms/Alias
Gene Name ARF1
Gene Synonyms/Alias YDL192W;D1244;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)
GTP-binding protein involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus. Recruits polyadenylate-binding protein PAB1 to COPI vesicles, and this is required for correct localization of the asymmetrically distributed ASH1 mRNA.
Phosphorylation Sites
dbPAF PTMs: 2
PositionPeptidesSourceReferences ( PMIDs )
135QDLPEAMSAAEITEKPhosphoGRID 2.0;curated21126336; 24961812
147TEKLGLHSIRNRPWFPhosphoGRID 2.0;SysPTM 2.0;curated20702584; 17563356; 18407956; 19366988; 22369663; 22817900;
Sequence
(Fasta)
MGLFASKLFS NLFGNKEMRI LMVGLDGAGK TTVLYKLKLG EVITTIPTIG FNVETVQYKN 60
ISFTVWDVGG QDRIRSLWRH YYRNTEGVIF VVDSNDRSRI GEAREVMQRM LNEDELRNAA 120
WLVFANKQDL PEAMSAAEIT EKLGLHSIRN RPWFIQATCA TSGEGLYEGL EWLSNSLKNS 180
T 182
Keyword

KW-0002--3D-structure
KW-0181--Complete proteome
KW-0931--ER-Golgi transport
KW-0333--Golgi apparatus
KW-0342--GTP-binding
KW-0449--Lipoprotein
KW-0519--Myristate
KW-0547--Nucleotide-binding
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0813--Transport

Interpro

IPR027417--P-loop_NTPase
IPR005225--Small_GTP-bd_dom
IPR024156--Small_GTPase_ARF
IPR006689--Small_GTPase_ARF/SAR

PROSITE

PS51417--ARF

Pfam

PF00025--Arf

Gene Ontology

GO:0005794--C:Golgi apparatus
GO:0005525--F:GTP binding
GO:0003924--F:GTPase activity
GO:0006888--P:ER to Golgi vesicle-mediated transport
GO:0006893--P:Golgi to plasma membrane transport
GO:0016236--P:macroautophagy
GO:0015031--P:protein transport
GO:0007264--P:small GTPase mediated signal transduction