dbPAF - database of Phospho-sites in Animals and Fungi

Protein
Gene
PTMs
Sequence
Keyword
GO
TOP

dbPAF Protein Information

Tag

Content

dbPAF ID

dbPAF-0005437

Uniprot Accession

P11075; SEC7_YEAST; D6VSF1; Q03960; Q04139;

Genbank Protein ID

NP_010454.3;

Genbank Nucleotide ID

NM_001180477.3;

Protein Name

Protein transport protein SEC7

Protein Synonyms/Alias

Gene Name

SEC7

Gene Synonyms/Alias

YDR170C;YD9395.01C;YD9489.05C;

Organism

Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)

NCBI Taxa ID

559292

Functional Description
(View all)

May play a role in vesicular budding and traffic between compartments of the Golgi apparatus.

Phosphorylation Sites

dbPAF PTMs: 66 (View all)

Position	Peptides	Source	References ( PMIDs )
2	------MSEQNSVVN	PhosphoGRID 2.0;PHOSIDA;curated	19823750; 19795423; 21081558; 26040289; 22369663; 24961812
6	--MSEQNSVVNAEKG	PHOSIDA;curated	21081558; 26040289; 19795423; 24961812
18	EKGDGEISSNVETAS	curated	19823750; 25315811
19	KGDGEISSNVETASS	curated	26040289; 22369663; 24961812; 25521595; 25315811; 20377248
23	EISSNVETASSVNPS	curated	25521595
25	SSNVETASSVNPSVK	curated	24961812
26	SNVETASSVNPSVKP	curated	25521595
59	KGPENAGSTAETKET	curated	25315811
66	STAETKETSNDATNG	curated	25315811
67	TAETKETSNDATNGM	curated	26040406; 22817900; 25315811
71	KETSNDATNGMKTPE	curated	24603354; 22817900
76	DATNGMKTPEETEDT	PhosphoGRID 2.0;curated	19779198; 26040406; 26040289; 22369663; 22817900; 24961812;
80	GMKTPEETEDTNDKR	curated	25315811
212	STHTRNISLSSNGSN	dbPTM 3.0;PhosphoGRID 2.0;PhosphoPep 2.0;SysPTM 2.0;UniProt;curated	15665377; 17330950; 18407956; 16381945; 23193290; 19684113;
214	HTRNISLSSNGSNTN	PhosphoPep 2.0;curated	19060867; 22817900; 25882841; 25315811
215	TRNISLSSNGSNTNS	dbPTM 3.0;PhosphoGRID 2.0;PhosphoPep 2.0;SysPTM 2.0;UniProt;curated	17330950; 18407956; 16381945; 23193290; 19684113; 19779198;
218	ISLSSNGSNTNSTII	dbPTM 3.0;PhosphoGRID 2.0;PhosphoPep 2.0;SysPTM 2.0;curated	18407956; 16381945; 23193290; 19060867; 19366988; 26040289;
220	LSSNGSNTNSTIILV	curated	22817900
334	QDAADGITPPPKQKI	dbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;UniProt;curated	18407956; 16381945; 23193290; 21126336; 19366988; 25315811
431	DKIDLKQSTSSAVSL	PhosphoGRID 2.0;curated	21126336; 19779198; 22369663; 22817900; 25315811; 19547744

Sequence
(Fasta)

MSEQNSVVNA EKGDGEISSN VETASSVNPS VKPQNAIKEE AKETNGEDQK CKGPENAGST 60
AETKETSNDA TNGMKTPEET EDTNDKRHDD EGEDGDEDED EDEDEDEDNG DEDDEDVDSS 120
SSETSSEDGE DSESVSGEST ESSSGEDEES DESDGNTSNS SSGDESGSEE EEEEEEEEEE 180
EENAGEPAIA HQDSVPTNDS TAPRSTHTRN ISLSSNGSNT NSTIILVKTT LETILNDKDI 240
KKNSNAQKAI ERTLQKFKEF DPQTTNNPHY VDSILVFEAL RASCRTKSSK VQSLALDCLS 300
KLFSFRSLDE TLLVNPPDSL ASNDQRQDAA DGITPPPKQK IIDAAIDTIS DCFQGEGTDD 360
RVELQIVRAL SSCILEEDSS SLCHGASLLK AIRTIYNVFV FSLNPSNQGI AQATLTQIIS 420
SVYDKIDLKQ STSSAVSLST KNHQQQSAIE LSEASENAET PAPLTLENMD KLNDDEERLM 480
DAQQPDSIAI TNQDLAVKDA FLVFRVMAKI CAKPLETELD MRSHAVRSKL LSLHIIYSII 540
KDHIDVFLSH NIFLPGKERV CFIDSIRQYL RLVLSRNAAS PLAPVFEVTL EIMWLLIANL 600
RADFVKEIPV FLTEIYFPIS ELTTSTSQQK RYFLSVIQRI CNDPRTLVEF YLNYDCNPGM 660
PNVMEITVDY LTRLALTRVE ITQTQRSYYD EQISKSLSTY NFSQLPLLTS SNLSSSPDVG 720
QVNLLFPLDF ALKMVSLNCI VSVLRSLSSW AHKALNPNTH TANKVLLNTT SSARQESRSS 780
LSNDVRSSIM TSNDDFKPTY EDEESRSLSS QNIDADDPTQ FENLKLRKTA LSECIAIFNN 840
KPKKAIPVLI KKGFLKDDSP ISIAKWLLET EGLDMAAVGD YLGEGDDKNI AIMHAFVDEF 900
DFTGMSIVDA LRSFLQSFRL PGEGQKIDRF MLKFAERFVD QNPGVFSKAD TAYVLSYSLI 960
MLNTDLHSSQ IKNKMSLQEF LENNEGIDNG RDLPRDFLEG LFNEIANNEI KLISEQHQAM 1020
LSGDTNLVQQ QQSAFNFFNS RDLTREAYNQ VSKEISSKTE LVFKNLNKNK GGPDVYYAAS 1080
HVEHVKSIFE TLWMSFLAAL TPPFKDYDDI DTTNKCLEGL KISIKIASTF RINDARTSFV 1140
GALVQFCNLQ NLEEIKVKNV NAMVILLEVA LSEGNYLEGS WKDILLVVSQ MERLQLISKG 1200
IDRDTVPDVA QARVANPRVS YESSRSNNTS FFDVWGKKAT PTELAQEKHH NQTLSPEISK 1260
FISSSELVVL MDNIFTKSSE LSGNAIVDFI KALTAVSLEE IESSENASTP RMFSLQKMVD 1320
VCYYNMDRIK LEWTPLWAVM GKAFNKIATN SNLAVVFFAI DSLRQLSMRF LDIEELSGFE 1380
FQHDFLKPFE YTVQNSGNTE VQEMIIECFR NFILTKSESI KSGWKPILES LQYTARSSTE 1440
SIVLKTQLLV SNDIVTNHFE NVFSQEDAFS ELVGVFREIT KNKRFQKLSL HALESLRKMT 1500
QNVADICFYN ENKTEEERKH NDALLRGKDI FQDVWFPMLF CFNDTIMTAE DLEVRSRALN 1560
YMFDALVAYG GKFNDDFWEK ICKKLLFPIF GVLSKHWEVN QFNSHDDLSV WLSTTLIQAL 1620
RNLIALFTHY FESLNRMLDG FLGLLVSCIC QENDTIARIG RSCLQQLILQ NVSKFNEYHW 1680
NQIGDVFDKL FDLTTANELF DYDPLQQGRK SSVSHHQTTN DTSQHSDDDS NDRRENDSNI 1740
SETVERAHQE ESSEDVGGDM VETLNGQTKL NNGNSVPTVK DELNPKPASL SIPKKTKHMK 1800
RNESNEDIRR RINIKNSIVV KCVLQLLMIE LLNELFENED FAHCIPYKEA IRITRLLEKS 1860
YEFSRDFNED YGLRTRLVEA RVVDKIPNLL KQETSAAAVL LDIMFQLYLN DDEKKADLIT 1920
RLITICIQVV EGYVSLDDRT MERSINAWRS VIVEILQGYY EFDDEDFRLY CPAMYALVIQ 1980
ILDKSVPTEL RHAIKQFLSR VGELYLSTD

Fasta Sequence

>P11075|SEC7|Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
MSEQNSVVNAEKGDGEISSNVETASSVNPSVKPQNAIKEEAKETNGEDQKCKGPENAGSTAETKETSNDATNGMKTPEETEDTNDKRHDDEGEDGDEDEDEDEDEDEDNGDEDDEDVDSSSSETSSEDGEDSESVSGESTESSSGEDEESDESDGNTSNSSSGDESGSEEEEEEEEEEEEEENAGEPAIAHQDSVPTNDSTAPRSTHTRNISLSSNGSNTNSTIILVKTTLETILNDKDIKKNSNAQKAIERTLQKFKEFDPQTTNNPHYVDSILVFEALRASCRTKSSKVQSLALDCLSKLFSFRSLDETLLVNPPDSLASNDQRQDAADGITPPPKQKIIDAAIDTISDCFQGEGTDDRVELQIVRALSSCILEEDSSSLCHGASLLKAIRTIYNVFVFSLNPSNQGIAQATLTQIISSVYDKIDLKQSTSSAVSLSTKNHQQQSAIELSEASENAETPAPLTLENMDKLNDDEERLMDAQQPDSIAITNQDLAVKDAFLVFRVMAKICAKPLETELDMRSHAVRSKLLSLHIIYSIIKDHIDVFLSHNIFLPGKERVCFIDSIRQYLRLVLSRNAASPLAPVFEVTLEIMWLLIANLRADFVKEIPVFLTEIYFPISELTTSTSQQKRYFLSVIQRICNDPRTLVEFYLNYDCNPGMPNVMEITVDYLTRLALTRVEITQTQRSYYDEQISKSLSTYNFSQLPLLTSSNLSSSPDVGQVNLLFPLDFALKMVSLNCIVSVLRSLSSWAHKALNPNTHTANKVLLNTTSSARQESRSSLSNDVRSSIMTSNDDFKPTYEDEESRSLSSQNIDADDPTQFENLKLRKTALSECIAIFNNKPKKAIPVLIKKGFLKDDSPISIAKWLLETEGLDMAAVGDYLGEGDDKNIAIMHAFVDEFDFTGMSIVDALRSFLQSFRLPGEGQKIDRFMLKFAERFVDQNPGVFSKADTAYVLSYSLIMLNTDLHSSQIKNKMSLQEFLENNEGIDNGRDLPRDFLEGLFNEIANNEIKLISEQHQAMLSGDTNLVQQQQSAFNFFNSRDLTREAYNQVSKEISSKTELVFKNLNKNKGGPDVYYAASHVEHVKSIFETLWMSFLAALTPPFKDYDDIDTTNKCLEGLKISIKIASTFRINDARTSFVGALVQFCNLQNLEEIKVKNVNAMVILLEVALSEGNYLEGSWKDILLVVSQMERLQLISKGIDRDTVPDVAQARVANPRVSYESSRSNNTSFFDVWGKKATPTELAQEKHHNQTLSPEISKFISSSELVVLMDNIFTKSSELSGNAIVDFIKALTAVSLEEIESSENASTPRMFSLQKMVDVCYYNMDRIKLEWTPLWAVMGKAFNKIATNSNLAVVFFAIDSLRQLSMRFLDIEELSGFEFQHDFLKPFEYTVQNSGNTEVQEMIIECFRNFILTKSESIKSGWKPILESLQYTARSSTESIVLKTQLLVSNDIVTNHFENVFSQEDAFSELVGVFREITKNKRFQKLSLHALESLRKMTQNVADICFYNENKTEEERKHNDALLRGKDIFQDVWFPMLFCFNDTIMTAEDLEVRSRALNYMFDALVAYGGKFNDDFWEKICKKLLFPIFGVLSKHWEVNQFNSHDDLSVWLSTTLIQALRNLIALFTHYFESLNRMLDGFLGLLVSCICQENDTIARIGRSCLQQLILQNVSKFNEYHWNQIGDVFDKLFDLTTANELFDYDPLQQGRKSSVSHHQTTNDTSQHSDDDSNDRRENDSNISETVERAHQEESSEDVGGDMVETLNGQTKLNNGNSVPTVKDELNPKPASLSIPKKTKHMKRNESNEDIRRRINIKNSIVVKCVLQLLMIELLNELFENEDFAHCIPYKEAIRITRLLEKSYEFSRDFNEDYGLRTRLVEARVVDKIPNLLKQETSAAAVLLDIMFQLYLNDDEKKADLITRLITICIQVVEGYVSLDDRTMERSINAWRSVIVEILQGYYEFDDEDFRLYCPAMYALVIQILDKSVPTELRHAIKQFLSRVGELYLSTD

Keyword

KW-0002--3D-structure
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0333--Golgi apparatus
KW-0597--Phosphoprotein
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0813--Transport

Interpro

IPR016024--ARM-type_fold
IPR032629--DCB_dom
IPR023394--Sec7_alpha_orthog
IPR015403--Sec7_C
IPR000904--Sec7_dom

PROSITE

PS50190--SEC7

Pfam

PF16213--DCB
PF09324--DUF1981
PF01369--Sec7

Gene Ontology

GO:0005829--C:cytosol
GO:0005798--C:Golgi-associated vesicle
GO:0005770--C:late endosome
GO:0005802--C:trans-Golgi network
GO:0005086--F:ARF guanyl-nucleotide exchange factor activity
GO:0000045--P:autophagosome assembly
GO:0006888--P:ER to Golgi vesicle-mediated transport
GO:0006891--P:intra-Golgi vesicle-mediated transport
GO:0043547--P:positive regulation of GTPase activity
GO:0015031--P:protein transport
GO:0032012--P:regulation of ARF protein signal transduction