dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0005411
Uniprot Accession P10870; SNF3_YEAST; D6VRF9;
Genbank Protein ID NP_010087.1;
Genbank Nucleotide ID NM_001180254.1;
Protein Name High-affinity glucose transporter SNF3
Protein Synonyms/Alias
Gene Name SNF3
Gene Synonyms/Alias YDL194W;D1234;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)		 High-affinity glucose transporter. Can function as a negative regulator of glucose transport. SNF3 is involved as well in the transport of mannose and fructose. Serves as a sensor that generates an intracellular signal in the presence of low level of glucose. Inhibition of RGT1 by low levels of glucose, and hence induction of HTX2 and HTX4 expression, requires SNF3.
Phosphorylation Sites
 dbPAF PTMs: 11
PositionPeptidesSourceReferences ( PMIDs )
559IDELYIKSSTGVVSPcurated22817900
561ELYIKSSTGVVSPKFPhosphoGRID 2.0;curated21177495; 22817900
621ISGEIDHSPNQKEVHcurated24961812; 25315811
629PNQKEVHSIPERVDIPhosphoGRID 2.0;curated19779198; 22817900; 24961812; 25315811; 20377248
645TSTEILESPNKSSGMcurated25315811; 20377248
678PAEIRTKYVDLGNGLcurated22817900
690NGLGLNTYNRGPPSLcurated22817900
720PSSQGDQSNRSTMNDdbPTM 3.0;SysPTM 2.018407956; 16381945; 23193290; 19366988
724GDQSNRSTMNDINDYdbPTM 3.0;SysPTM 2.018407956; 16381945; 23193290; 19366988
740ARLIHSTSTASNTTDcurated22369663
743IHSTSTASNTTDKFScurated22369663
Sequence
(Fasta)		MDPNSNSSSE TLRQEKQGFL DKALQRVKGI ALRRNNSNKD HTTDDTTGSI RTPTSLQRQN 60
SDRQSNMTSV FTDDISTIDD NSILFSEPPQ KQSMMMSICV GVFVAVGGFL FGYDTGLINS 120
ITSMNYVKSH VAPNHDSFTA QQMSILVSFL SLGTFFGALT APFISDSYGR KPTIIFSTIF 180
IFSIGNSLQV GAGGITLLIV GRVISGIGIG AISAVVPLYQ AEATHKSLRG AIISTYQWAI 240
TWGLLVSSAV SQGTHARNDA SSYRIPIGLQ YVWSSFLAIG MFFLPESPRY YVLKDKLDEA 300
AKSLSFLRGV PVHDSGLLEE LVEIKATYDY EASFGSSNFI DCFISSKSRP KQTLRMFTGI 360
ALQAFQQFSG INFIFYYGVN FFNKTGVSNS YLVSFITYAV NVVFNVPGLF FVEFFGRRKV 420
LVVGGVIMTI ANFIVAIVGC SLKTVAAAKV MIAFICLFIA AFSATWGGVV WVISAELYPL 480
GVRSKCTAIC AAANWLVNFI CALITPYIVD TGSHTSSLGA KIFFIWGSLN AMGVIVVYLT 540
VYETKGLTLE EIDELYIKSS TGVVSPKFNK DIRERALKFQ YDPLQRLEDG KNTFVAKRNN 600
FDDETPRNDF RNTISGEIDH SPNQKEVHSI PERVDIPTST EILESPNKSS GMTVPVSPSL 660
QDVPIPQTTE PAEIRTKYVD LGNGLGLNTY NRGPPSLSSD SSEDYTEDEI GGPSSQGDQS 720
NRSTMNDIND YMARLIHSTS TASNTTDKFS GNQSTLRYHT ASSHSDTTEE DSNLMDLGNG 780
LALNAYNRGP PSILMNSSDE EANGGETSDN LNTAQDLAGM KERMAQFAQS YIDKRGGLEP 840
ETQSNILSTS LSVMADTNEH NNEILHSSEE NATNQPVNEN NDLK 885
Keyword

KW-1003--Cell membrane
KW-0181--Complete proteome
KW-0325--Glycoprotein
KW-0472--Membrane
KW-1185--Reference proteome
KW-0762--Sugar transport
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0813--Transport
Interpro

IPR020846--MFS_dom
IPR005828--MFS_sugar_transport_like
IPR003663--Sugar/inositol_transpt
IPR005829--Sugar_transporter_CS
PROSITE

PS50850--MFS
PS00216--SUGAR_TRANSPORT_1
PS00217--SUGAR_TRANSPORT_2
Pfam

PF00083--Sugar_tr
Gene Ontology

GO:0005887--C:integral component of plasma membrane
GO:0005886--C:plasma membrane
GO:0005536--F:glucose binding
GO:0004872--F:receptor activity
GO:0005351--F:sugar:proton symporter activity
GO:0051594--P:detection of glucose
GO:0015755--P:fructose transport
GO:0046323--P:glucose import
GO:0010255--P:glucose mediated signaling pathway
GO:0015758--P:glucose transport
GO:0035428--P:hexose transmembrane transport
GO:0015761--P:mannose transport
GO:0045835--P:negative regulation of meiotic nuclear division
GO:0015992--P:proton transport
GO:0007165--P:signal transduction