dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0005410
Uniprot Accession P10869; AK_YEAST; D3DLV4;
Genbank Protein ID NP_010972.1;
Genbank Nucleotide ID NM_001178943.1;
Protein Name Aspartokinase
Protein Synonyms/Alias Aspartate kinase;
Gene Name HOM3
Gene Synonyms/Alias YER052C;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)
Phosphorylation Sites
 dbPAF PTMs: 16
PositionPeptidesSourceReferences ( PMIDs )
22VVQKFGGTSVGKFPVcurated22369663
332NVAKKGESTPPHPPEdbPTM 3.0;PhosphoGRID 2.0;PHOSIDA;PhosphoPep 2.0;SysPTM 2.0;curated17330950; 16381945; 23193290; 21126336; 20702584; 19684113;
333VAKKGESTPPHPPENdbPTM 3.0;PhosphoGRID 2.0;PHOSIDA;PhosphoPep 2.0;SysPTM 2.0;UniProt;curated17287358; 17330950; 18407956; 16381945; 23193290; 21177495;
342PHPPENLSSSFYEKRPhosphoGRID 2.0;PhosphoPep 2.0;curated21177495; 19779198; 19060867; 26040406; 24603354; 22817900;
343HPPENLSSSFYEKRKPhosphoGRID 2.0;PhosphoPep 2.0;curated21177495; 19060867; 22817900; 23825934; 20377248
344PPENLSSSFYEKRKRdbPTM 3.0;PhosphoGRID 2.0;PHOSIDA;PhosphoPep 2.0;SysPTM 2.0;curated17330950; 16381945; 23193290; 21177495; 20702584; 19823750;
346ENLSSSFYEKRKRGAPhosphoGRID 2.0;PhosphoPep 2.0;curated21177495; 19060867; 26040406; 22817900; 23825934
354EKRKRGATAITTKNDPhosphoGRID 2.0;curated21177495; 22817900
357KRGATAITTKNDIFVPhosphoGRID 2.0;curated21177495; 22817900
369IFVINIHSNKKTLSHPhosphoGRID 2.0;curated21177495; 22817900
373NIHSNKKTLSHGFLAcurated19823750
384GFLAQIFTILDKYKLcurated22817900; 19823750
441TKKLSIVSLVGKHMKdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 19366988
505AKLLSERTNTSNQFEPhosphoGRID 2.0;curated19779198; 22369663; 22817900; 23825934
507LLSERTNTSNQFEHAcurated22369663; 22817900; 19547744
508LSERTNTSNQFEHAIcurated25315811
Sequence
(Fasta)		MPMDFQPTSS HSNWVVQKFG GTSVGKFPVQ IVDDIVKHYS KPDGPNNNVA VVCSARSSYT 60
KAEGTTSRLL KCCDLASQES EFQDIIEVIR QDHIDNADRF ILNPALQAKL VDDTNKELEL 120
VKKYLNASKV LGEVSSRTVD LVMSCGEKLS CLFMTALCND RGCKAKYVDL SHIVPSDFSA 180
SALDNSFYTF LVQALKEKLA PFVSAKERIV PVFTGFFGLV PTGLLNGVGR GYTDLCAALI 240
AVAVNADELQ VWKEVDGIFT ADPRKVPEAR LLDSVTPEEA SELTYYGSEV IHPFTMEQVI 300
RAKIPIRIKN VQNPLGNGTI IYPDNVAKKG ESTPPHPPEN LSSSFYEKRK RGATAITTKN 360
DIFVINIHSN KKTLSHGFLA QIFTILDKYK LVVDLISTSE VHVSMALPIP DADSLKSLRQ 420
AEEKLRILGS VDITKKLSIV SLVGKHMKQY IGIAGTMFTT LAEEGINIEM ISQGANEINI 480
SCVINESDSI KALQCIHAKL LSERTNTSNQ FEHAIDERLE QLKRLGI 528
Keyword

KW-0028--Amino-acid biosynthesis
KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
KW-0791--Threonine biosynthesis
KW-0808--Transferase
Interpro

IPR002912--ACT_dom
IPR001048--Asp/Glu/Uridylate_kinase
IPR001341--Asp_kinase_dom
IPR018042--Aspartate_kinase_CS
IPR027795--GATS-like_ACT_dom
PROSITE

PS51671--ACT
PS00324--ASPARTOKINASE
Pfam

PF00696--AA_kinase
PF13840--ACT_7
Gene Ontology

GO:0016597--F:amino acid binding
GO:0004072--F:aspartate kinase activity
GO:0005524--F:ATP binding
GO:0009090--P:homoserine biosynthetic process
GO:0009089--P:lysine biosynthetic process via diaminopimelate
GO:0009086--P:methionine biosynthetic process
GO:0009088--P:threonine biosynthetic process