dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0005375
Uniprot Accession P10659; METK1_YEAST; D6VYI4;
Genbank Protein ID NP_013281.1;
Genbank Nucleotide ID NM_001182067.1;
Protein Name S-adenosylmethionine synthase 1
Protein Synonyms/Alias
Gene Name SAM1
Gene Synonyms/Alias ETH10;YLR180W;L9470.9;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)		 Catalyzes the formation of S-adenosylmethionine from methionine and ATP.
Phosphorylation Sites
 dbPAF PTMs: 10
PositionPeptidesSourceReferences ( PMIDs )
4----MAGTFLFTSEScurated22369663; 24961812
101LVAIEQQSPDIAQGVcurated22369663
169WLRPDTKTQVTVEYKcurated26040406
172PDTKTQVTVEYKDDHcurated26040406
175KTQVTVEYKDDHGRWcurated26040406
234TKYFIQPSGRFVIGGPhosphoGRID 2.0;PhosphoPep 2.0;curated19779198; 19060867; 22369663; 22817900
262VDAYGGASSVGGGAFcurated22817900
263DAYGGASSVGGGAFScurated22817900
291AARWVAKSLVAAGLCPhosphoGRID 2.0;curated19779198; 22817900
337EEIIDIISKNFDLRPcurated24961812
Sequence
(Fasta)		MAGTFLFTSE SVGEGHPDKI CDQVSDAILD ACLAEDPHSK VACETAAKTG MIMVFGEITT 60
KAQLDYQKIV RDTIKKIGYD DSAKGFDYKT CNVLVAIEQQ SPDIAQGVHE EKDLEDIGAG 120
DQGIMFGYAT DETPEGLPLT ILLAHKLNMA MADARRDGSL AWLRPDTKTQ VTVEYKDDHG 180
RWVPQRIDTV VVSAQHADEI TTEDLRAQLK SEIIEKVIPR DMLDENTKYF IQPSGRFVIG 240
GPQGDAGLTG RKIIVDAYGG ASSVGGGAFS GKDYSKVDRS AAYAARWVAK SLVAAGLCKR 300
VQVQFSYAIG IAEPLSLHVD TYGTATKSDE EIIDIISKNF DLRPGVLVKE LDLARPIYLP 360
TASYGHFTNQ EYPWEKPKTL KF 383
Keyword

KW-0067--ATP-binding
KW-0170--Cobalt
KW-0181--Complete proteome
KW-0903--Direct protein sequencing
KW-0460--Magnesium
KW-0479--Metal-binding
KW-0547--Nucleotide-binding
KW-0554--One-carbon metabolism
KW-0630--Potassium
KW-1185--Reference proteome
KW-0808--Transferase
Interpro

IPR022631--ADOMET_SYNTHASE_CS
IPR022630--S-AdoMet_synt_C
IPR022629--S-AdoMet_synt_central
IPR022628--S-AdoMet_synt_N
IPR002133--S-AdoMet_synthetase
IPR022636--S-AdoMet_synthetase_sfam
PROSITE

PS00376--ADOMET_SYNTHASE_1
PS00377--ADOMET_SYNTHASE_2
Pfam

PF02773--S-AdoMet_synt_C
PF02772--S-AdoMet_synt_M
PF00438--S-AdoMet_synt_N
Gene Ontology

GO:0005829--C:cytosol
GO:0005524--F:ATP binding
GO:0046872--F:metal ion binding
GO:0004478--F:methionine adenosyltransferase activity
GO:0006555--P:methionine metabolic process
GO:0006730--P:one-carbon metabolic process
GO:0006556--P:S-adenosylmethionine biosynthetic process