| Tag |
Content |
| dbPAF ID |
dbPAF-0005360 |
| Uniprot Accession |
P10627; TWIST_DROME; Q1LZ34; Q8MT07; Q8T8Y9; Q9W1W1;
|
| Genbank Protein ID |
NP_001033967.1; NP_001286752.1; NP_523816.2;
|
| Genbank Nucleotide ID |
NM_001038878.2; NM_001299823.1; NM_079092.3;
|
| Protein Name |
Protein twist |
| Protein Synonyms/Alias |
|
| Gene Name |
twi |
| Gene Synonyms/Alias |
CG2956; |
| Organism |
Drosophila melanogaster(Fruit fly) |
| NCBI Taxa ID |
7227 |
Functional Description
(View all) |
Involved in the establishment and dorsoventral patterning of germ layers in the embryo.Functional Description
Involved in the establishment and dorsoventral patterning of germ layers in the embryo. |
Phosphorylation Sites
|
dbPAF PTMs: 2 |
Sequence
(Fasta) | MMSARSVSPK VLLDISYKPT LPNIMELQNN VIKLIQVEQQ AYMQSGYQLQ HQQQHLHSHQ 60
HHQQHHQQQH AQYAPLPSEY AAYGITELED TDYNIPSNEV LSTSSNQSAQ STSLELNNNN 120
TSSNTNSSGN NPSGFDGQAS SGSSWNEHGK RARSSGDYDC QTGGSLVMQP EHKKLIHQQQ 180
QQQQQHQQQI YVDYLPTTVD EVASAQSCPG VQSTCTSPQS HFDFPDEELP EHKAQVFLPL 240
YNNQQQQSQQ LQQQQPHQQS HAQMHFQNAY RQSFEGYEPA NSLNGSAYSS SDRDDMEYAR 300
HNALSSVSDL NGGVMSPACL ADDGSAGSLL DGSDAGGKAF RKPRRRLKRK PSKTEETDEF 360
SNQRVMANVR ERQRTQSLND AFKSLQQIIP TLPSDKLSKI QTLKLATRYI DFLCRMLSSS 420
DISLLKALEA QGSPSAYGSA SSLLSAAANG AEADLKCLRK ANGAPIIPPE KLSYLFGVWR 480
MEGDAQHQKA
491Fasta Sequence
>P10627|twi|Drosophila melanogaster(Fruit fly)
MMSARSVSPKVLLDISYKPTLPNIMELQNNVIKLIQVEQQAYMQSGYQLQHQQQHLHSHQHHQQHHQQQHAQYAPLPSEYAAYGITELEDTDYNIPSNEVLSTSSNQSAQSTSLELNNNNTSSNTNSSGNNPSGFDGQASSGSSWNEHGKRARSSGDYDCQTGGSLVMQPEHKKLIHQQQQQQQQHQQQIYVDYLPTTVDEVASAQSCPGVQSTCTSPQSHFDFPDEELPEHKAQVFLPLYNNQQQQSQQLQQQQPHQQSHAQMHFQNAYRQSFEGYEPANSLNGSAYSSSDRDDMEYARHNALSSVSDLNGGVMSPACLADDGSAGSLLDGSDAGGKAFRKPRRRLKRKPSKTEETDEFSNQRVMANVRERQRTQSLNDAFKSLQQIIPTLPSDKLSKIQTLKLATRYIDFLCRMLSSSDISLLKALEAQGSPSAYGSASSLLSAAANGAEADLKCLRKANGAPIIPPEKLSYLFGVWRMEGDAQHQKA
|
| Keyword |
KW-0181--Complete proteome
KW-0217--Developmental protein
KW-0221--Differentiation
KW-0238--DNA-binding
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0804--Transcription
KW-0805--Transcription regulation
|
| Interpro |
IPR011598--bHLH_dom
IPR015789--Twist-related
|
| PROSITE |
PS50888--BHLH
|
| Pfam |
PF00010--HLH
|
| Gene Ontology |
GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0003677--F:DNA binding
GO:0046982--F:protein heterodimerization activity
GO:0042803--F:protein homodimerization activity
GO:0003705--F:transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
GO:0031032--P:actomyosin structure organization
GO:0009950--P:dorsal/ventral axis specification
GO:0007499--P:ectoderm and mesoderm interaction
GO:0007369--P:gastrulation
GO:0010004--P:gastrulation involving germ band extension
GO:0007507--P:heart development
GO:0007443--P:Malpighian tubule morphogenesis
GO:0007498--P:mesoderm development
GO:0001710--P:mesodermal cell fate commitment
GO:0007500--P:mesodermal cell fate determination
GO:0007501--P:mesodermal cell fate specification
GO:0048747--P:muscle fiber development
GO:0010629--P:negative regulation of gene expression
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0016202--P:regulation of striated muscle tissue development
GO:0007435--P:salivary gland morphogenesis
GO:0006351--P:transcription, DNA-templated
GO:0007370--P:ventral furrow formation
|
