dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0005350
Uniprot Accession P10592; HSP72_YEAST; D6VXY0;
Genbank Protein ID NP_013076.1;
Genbank Nucleotide ID NM_001181844.1;
Protein Name Heat shock protein SSA2
Protein Synonyms/Alias
Gene Name SSA2
Gene Synonyms/Alias YLL024C;L0931;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)		 May play a role in the transport of polypeptides both across the mitochondrial membranes and into the endoplasmic reticulum. A functional difference between SSA1 and SSA2 proteins is expected. SSA2 can participate in the ATP-dependent disassembly of clathrin-coated vesicles.
Phosphorylation Sites
 dbPAF PTMs: 13
PositionPeptidesSourceReferences ( PMIDs )
12VGIDLGTTYSCVAHFcurated17287358
14IDLGTTYSCVAHFSNcurated17287358
20YSCVAHFSNDRVDIIdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;UniProt;curated18407956; 16381945; 23193290; 19366988; 17287358
35ANDQGNRTTPSFVGFdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 21126336; 19366988
36NDQGNRTTPSFVGFTdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 19366988; 22817900; 26040289
38QGNRTTPSFVGFTDTcurated25315811
45SFVGFTDTERLIGDAPhosphoGRID 2.011283598
422STIPTKKSEVFSTYAPhosphoPep 2.0;SysPTM 2.0;curated19060867; 18407956; 19366988; 24961812; 25521595; 20377248
426TKKSEVFSTYADNQPdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;curated17287358; 16381945; 23193290; 19366988; 22817900
428KSEVFSTYADNQPGVcurated25521595
549IAYSLKNTISEAGDKPhosphoPep 2.019060867
551YSLKNTISEAGDKLEdbPTM 3.0;PhosphoPep 2.0;SysPTM 2.0;curated15665377; 17563356; 18407956; 16381945; 23193290; 19060867;
603EVANPIMSKLYQAGGcurated24961812; 25315811
Sequence
(Fasta)		MSKAVGIDLG TTYSCVAHFS NDRVDIIAND QGNRTTPSFV GFTDTERLIG DAAKNQAAMN 60
PANTVFDAKR LIGRNFNDPE VQGDMKHFPF KLIDVDGKPQ IQVEFKGETK NFTPEQISSM 120
VLGKMKETAE SYLGAKVNDA VVTVPAYFND SQRQATKDAG TIAGLNVLRI INEPTAAAIA 180
YGLDKKGKEE HVLIFDLGGG TFDVSLLSIE DGIFEVKATA GDTHLGGEDF DNRLVNHFIQ 240
EFKRKNKKDL STNQRALRRL RTACERAKRT LSSSAQTSVE IDSLFEGIDF YTSITRARFE 300
ELCADLFRST LDPVEKVLRD AKLDKSQVDE IVLVGGSTRI PKVQKLVTDY FNGKEPNRSI 360
NPDEAVAYGA AVQAAILTGD ESSKTQDLLL LDVAPLSLGI ETAGGVMTKL IPRNSTIPTK 420
KSEVFSTYAD NQPGVLIQVF EGERAKTKDN NLLGKFELSG IPPAPRGVPQ IEVTFDVDSN 480
GILNVSAVEK GTGKSNKITI TNDKGRLSKE DIEKMVAEAE KFKEEDEKES QRIASKNQLE 540
SIAYSLKNTI SEAGDKLEQA DKDAVTKKAE ETIAWLDSNT TATKEEFDDQ LKELQEVANP 600
IMSKLYQAGG APEGAAPGGF PGGAPPAPEA EGPTVEEVD
Keyword

KW-0007--Acetylation
KW-0067--ATP-binding
KW-0134--Cell wall
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0903--Direct protein sequencing
KW-1017--Isopeptide bond
KW-0547--Nucleotide-binding
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0964--Secreted
KW-0346--Stress response
KW-0832--Ubl conjugation
Interpro

IPR018181--Heat_shock_70_CS
IPR029048--HSP70_C
IPR029047--HSP70_peptide-bd
IPR013126--Hsp_70_fam
PROSITE

PS00297--HSP70_1
PS00329--HSP70_2
PS01036--HSP70_3
Pfam

PF00012--HSP70
Gene Ontology

GO:0005737--C:cytoplasm
GO:0005829--C:cytosol
GO:0005576--C:extracellular region
GO:0009277--C:fungal-type cell wall
GO:0000329--C:fungal-type vacuole membrane
GO:0005739--C:mitochondrion
GO:0005844--C:polysome
GO:0005524--F:ATP binding
GO:0016887--F:ATPase activity
GO:0000049--F:tRNA binding
GO:0051082--F:unfolded protein binding
GO:0006457--P:protein folding
GO:0006616--P:SRP-dependent cotranslational protein targeting to membrane, translocation
GO:0035719--P:tRNA import into nucleus