dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0005349
Uniprot Accession P10591; HSP71_YEAST; D6VPL2;
Genbank Protein ID NP_009396.2;
Genbank Nucleotide ID NM_001178151.1;
Protein Name Heat shock protein SSA1
Protein Synonyms/Alias Heat shock protein YG100;
Gene Name SSA1
Gene Synonyms/Alias YAL005C;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)		 May play a role in the transport of polypeptides both across the mitochondrial membranes and into the endoplasmic reticulum. A functional difference between SSA1 and SSA2 proteins is expected. SSA1 can participate in the ATP-dependent disassembly of clathrin-coated vesicles.
Phosphorylation Sites
 dbPAF PTMs: 28 (View all)
PositionPeptidesSourceReferences ( PMIDs )
12VGIDLGTTYSCVAHFdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;curated17287358; 16381945; 23193290; 19366988
14IDLGTTYSCVAHFANPhosphoGRID 2.017287358
35ANDQGNRTTPSFVAFdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 21126336; 19366988; 22369663;
36NDQGNRTTPSFVAFTdbPTM 3.0;PhosphoGRID 2.0;PhosphoPep 2.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 19060867; 19366988; 22369663;
38QGNRTTPSFVAFTDTcurated22817900; 19547744
43TPSFVAFTDTERLIGdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 19366988; 22369663
45SFVAFTDTERLIGDAcurated22369663
62NQAAMNPSNTVFDAKdbPTM 3.0;PhosphoGRID 2.0;PhosphoPep 2.0;SysPTM 2.0;UniProt;curated18407956; 16381945; 23193290; 21126336; 19060867; 19366988;
64AAMNPSNTVFDAKRLPhosphoPep 2.019060867
131KMKETAESYLGAKVNdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 19366988
132MKETAESYLGAKVNDPhosphoPep 2.019060867
151VPAYFNDSQRQATKDdbPTM 3.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 19366988
326RDAKLDKSQVDEIVLPhosphoGRID 2.0;curated19779198; 22817900; 25521595; 24961812
337EIVLVGGSTRIPKVQcurated25521595
338IVLVGGSTRIPKVQKcurated25521595
378AVQAAILTGDESSKTdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 19366988
383ILTGDESSKTQDLLLcurated20377248
422STIPTKKSEIFSTYAcurated22369663; 24961812
459LLGKFELSGIPPAPRdbPTM 3.018407956; 16381945; 23193290
486SNGILNVSAVEKGTGdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 19366988; 26040406
Sequence
(Fasta)		MSKAVGIDLG TTYSCVAHFA NDRVDIIAND QGNRTTPSFV AFTDTERLIG DAAKNQAAMN 60
PSNTVFDAKR LIGRNFNDPE VQADMKHFPF KLIDVDGKPQ IQVEFKGETK NFTPEQISSM 120
VLGKMKETAE SYLGAKVNDA VVTVPAYFND SQRQATKDAG TIAGLNVLRI INEPTAAAIA 180
YGLDKKGKEE HVLIFDLGGG TFDVSLLSIE DGIFEVKATA GDTHLGGEDF DNRLVNHFIQ 240
EFKRKNKKDL STNQRALRRL RTACERAKRT LSSSAQTSVE IDSLFEGIDF YTSITRARFE 300
ELCADLFRST LDPVEKVLRD AKLDKSQVDE IVLVGGSTRI PKVQKLVTDY FNGKEPNRSI 360
NPDEAVAYGA AVQAAILTGD ESSKTQDLLL LDVAPLSLGI ETAGGVMTKL IPRNSTIPTK 420
KSEIFSTYAD NQPGVLIQVF EGERAKTKDN NLLGKFELSG IPPAPRGVPQ IEVTFDVDSN 480
GILNVSAVEK GTGKSNKITI TNDKGRLSKE DIEKMVAEAE KFKEEDEKES QRIASKNQLE 540
SIAYSLKNTI SEAGDKLEQA DKDTVTKKAE ETISWLDSNT TASKEEFDDK LKELQDIANP 600
IMSKLYQAGG APGGAAGGAP GGFPGGAPPA PEAEGPTVEE VD 643
Keyword

KW-0002--3D-structure
KW-0007--Acetylation
KW-0067--ATP-binding
KW-0134--Cell wall
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0903--Direct protein sequencing
KW-1017--Isopeptide bond
KW-0547--Nucleotide-binding
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0964--Secreted
KW-0346--Stress response
KW-0832--Ubl conjugation
Interpro

IPR018181--Heat_shock_70_CS
IPR029048--HSP70_C
IPR029047--HSP70_peptide-bd
IPR013126--Hsp_70_fam
PROSITE

PS00297--HSP70_1
PS00329--HSP70_2
PS01036--HSP70_3
Pfam

PF00012--HSP70
Gene Ontology

GO:0005737--C:cytoplasm
GO:0005576--C:extracellular region
GO:0009277--C:fungal-type cell wall
GO:0000329--C:fungal-type vacuole membrane
GO:0005634--C:nucleus
GO:0005844--C:polysome
GO:0005524--F:ATP binding
GO:0016887--F:ATPase activity
GO:0000049--F:tRNA binding
GO:0051082--F:unfolded protein binding
GO:0072318--P:clathrin coat disassembly
GO:0002181--P:cytoplasmic translation
GO:0006457--P:protein folding
GO:0000060--P:protein import into nucleus, translocation
GO:0000209--P:protein polyubiquitination
GO:0042026--P:protein refolding
GO:0006626--P:protein targeting to mitochondrion
GO:0006616--P:SRP-dependent cotranslational protein targeting to membrane, translocation
GO:0035617--P:stress granule disassembly