dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0005341
Uniprot Accession P10507; MPPB_YEAST; D6VYG9;
Genbank Protein ID NP_013264.1;
Genbank Nucleotide ID NM_001182050.1;
Protein Name Mitochondrial-processing peptidase subunit beta
Protein Synonyms/Alias Beta-MPP;PEP;
Gene Name MAS1
Gene Synonyms/Alias MIF1;YLR163C;L9632.10;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)
Cleaves presequences (transit peptides) from mitochondrial protein precursors.
Phosphorylation Sites
dbPAF PTMs: 3
PositionPeptidesSourceReferences ( PMIDs )
235YFGHVPKSESPVPLGPhosphoGRID 2.021126336
237GHVPKSESPVPLGSPcurated25315811
243ESPVPLGSPRGPLPVdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;UniProt;curated18407956; 16381945; 23193290; 19366988; 22369663; 25315811
Sequence
(Fasta)
MFSRTASKFR NTRRLLSTIS SQIPGTRTSK LPNGLTIATE YIPNTSSATV GIFVDAGSRA 60
ENVKNNGTAH FLEHLAFKGT QNRSQQGIEL EIENIGSHLN AYTSRENTVY YAKSLQEDIP 120
KAVDILSDIL TKSVLDNSAI ERERDVIIRE SEEVDKMYDE VVFDHLHEIT YKDQPLGRTI 180
LGPIKNIKSI TRTDLKDYIT KNYKGDRMVL AGAGAVDHEK LVQYAQKYFG HVPKSESPVP 240
LGSPRGPLPV FCRGERFIKE NTLPTTHIAI ALEGVSWSAP DYFVALATQA IVGNWDRAIG 300
TGTNSPSPLA VAASQNGSLA NSYMSFSTSY ADSGLWGMYI VTDSNEHNVQ LIVNEILKEW 360
KRIKSGKISD AEVNRAKAQL KAALLLSLDG STAIVEDIGR QVVTTGKRLS PEEVFEQVDK 420
ITKDDIIMWA NYRLQNKPVS MVALGNTSTV PNVSYIEEKL NQ 463
Keyword

KW-0002--3D-structure
KW-0181--Complete proteome
KW-0903--Direct protein sequencing
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0482--Metalloprotease
KW-0496--Mitochondrion
KW-0597--Phosphoprotein
KW-0645--Protease
KW-1185--Reference proteome
KW-0809--Transit peptide
KW-0862--Zinc

Interpro

IPR011249--Metalloenz_LuxS/M16
IPR011237--Pept_M16_dom
IPR011765--Pept_M16_N
IPR001431--Pept_M16_Zn_BS
IPR007863--Peptidase_M16_C

PROSITE

PS00143--INSULINASE

Pfam

PF00675--Peptidase_M16
PF05193--Peptidase_M16_C

Gene Ontology

GO:0005759--C:mitochondrial matrix
GO:0017087--C:mitochondrial processing peptidase complex
GO:0004222--F:metalloendopeptidase activity
GO:0008270--F:zinc ion binding
GO:0006627--P:protein processing involved in protein targeting to mitochondrion