| Tag |
Content |
| dbPAF ID |
dbPAF-0005310 |
| Uniprot Accession |
P10180; CUT_DROME; Q9W3Q6;
|
| Genbank Protein ID |
NP_524764.1;
|
| Genbank Nucleotide ID |
NM_080025.2;
|
| Protein Name |
Homeobox protein cut |
| Protein Synonyms/Alias |
|
| Gene Name |
ct |
| Gene Synonyms/Alias |
CG11387; |
| Organism |
Drosophila melanogaster(Fruit fly) |
| NCBI Taxa ID |
7227 |
Functional Description
(View all) |
Regulator of cell fate decisions in multiple lineages. Specifically, functions as a determination factor that specifies sensory organ identity in precursor cells. Probably also involved in cell type specification of Malpighian tubules. In absence of cut gene external sensory organs are transformed into chordotonal organs.Functional Description
Regulator of cell fate decisions in multiple lineages. Specifically, functions as a determination factor that specifies sensory organ identity in precursor cells. Probably also involved in cell type specification of Malpighian tubules. In absence of cut gene external sensory organs are transformed into chordotonal organs. |
Phosphorylation Sites
|
dbPAF PTMs: 6 |
Sequence
(Fasta) | MQPTLPQAAG TADMDLTAVQ SINDWFFKKE QIYLLAQFWQ QRATLAEKEV NTLKEQLSTG 60
NPDSNLNSEN SDTAAAAATA AAVAAVVAGA TATNDIEDEQ QQQLQQTASG GILESDSDKL 120
LNSSIVAAAI TLQQQNGSNL LANTNTPSPS PPLLSAEQQQ QLQSSLQQSG GVGGACLNPK 180
LFFNHAQQMM MMEAAAAAAA AALQQQQQQQ SPLHSPANEV AIPTEQPAAT VATGAAAAAA 240
AAATPIATGN VKSGSTTSNA NHTNSNNSHQ DEEELDDEEE DEEEDEDEDD EEENASMQSN 300
ADDMELDAQQ ETRTEPSATT QQQHQQQDTE DLEENKDAGE ASLNVSNNHN TTDSNNSCSR 360
KNNNGGNESE QHVASSAEDD DCANNNTNTS NNNNTSNTAT SNTNNNNNNN SSSGNSEKRK 420
KKNNNNNNGQ PAVLLAAKDK EIKALLDELQ RLRAQEQTHL VQIQRLEEHL EVKRQHIIRL 480
EARLDKQQIN EALAEATALS AAASTNNNNN SQSSDNNKKL NTAAERPMDA SSNADLPEST 540
KAPVPAEDDE EDEDQAMLVD SEEAEDKPED SHHDDDEDED EDREAVNATT TDSNELKIKK 600
EQHSPLDLNV LSPNSAIAAA AAAAAAAACA NDPNKFQALL IERTKALAAE ALKNGASDAL 660
SEDAHHQQQQ HHQQQHQHQQ QHHQQQHLHQ QHHHHLQQQP NSGSNSNPAS NDHHHGHHLH 720
GHGLLHPSSA HHLHHQTTES NSNSSTPTAA GNNNGSNNSS SNTNANSTAQ LAASLASTLN 780
GTKSLMQEDS NGLAAVAMAA HAQHAAALGP GFLPGLPAFQ FAAAQVAAGG DGRGHYRFAD 840
SELQLPPGAS MAGRLGESLI PKGDPMEAKL QEMLRYNMDK YANQALDTLH ISRRVRELLS 900
VHNIGQRLFA KYILGLSQGT VSELLSKPKP WDKLTEKGRD SYRKMHAWAC DDNAVMLLKS 960
LIPKKDSGLP QYAGRGAGGA GGDDSMSEDR IAHILSEASS LMKQSSVAQH REQERRSHGG 1020
EDSHSNEDSK SPPQSCTSPF FKVENQLKQH QHLNPEQAAA QQREREREQR EREQQQRLRH 1080
DDQDKMARLY QELIARTPRE TAFPSFLFSP SLFGGAAGMP GAASNAFPAM ADENMRHVFE 1140
REIAKLQQHQ QQQQAAQAQA QFPNFSSLMA LQQQVLNGAQ DLSLAAAAAK DIKLNGQRSS 1200
LEHSAGSSSC SKDGERDDAY PSSLHGRKSE GGGTPAPPAP PSGPGTGAGA PPTAAPPTGG 1260
ASSNSAAPSP LSNSILPPAL SSQGEEFAAT ASPLQRMASI TNSLITQPPV TPHHSTPQRP 1320
TKAVLPPITQ QQFDMFNNLN TEDIVRRVKE ALSQYSISQR LFGESVLGLS QGSVSDLLAR 1380
PKPWHMLTQK GREPFIRMKM FLEDENAVHK LVASQYKIAP EKLMRTGSYS GSPQMPQGLA 1440
SKMQAASLPM QKMMSELKLQ EPAQAQHLMQ QMQAAAMSAA MQQQQVAQAQ QQAQQAQQAQ 1500
QHLQQQAQQH LQQQQHLAQQ QHPHQQHHQA AAAAAALHHQ SMLLTSPGLP PQHAISLPPS 1560
AGGAQPGGPG GNQGSSNPSN SEKKPMLMPV HGTNAMRSLH QHMSPTVYEM AALTQDLDTH 1620
DITTKIKEAL LANNIGQKIF GEAVLGLSQG SVSELLSKPK PWHMLSIKGR EPFIRMQLWL 1680
SDANNVERLQ LLKNERREAS KRRRSTGPNQ QDNSSDTSSN DTNDFYTSSP GPGSVGSGVG 1740
GAPPSKKQRV LFSEEQKEAL RLAFALDPYP NVGTIEFLAN ELGLATRTIT NWFHNHRMRL 1800
KQQVPHGPAG QDNPIPSRES TSATPFDPVQ FRILLQQRLL ELHKERMGMS GAPIPYPPYF 1860
AAAAILGRSL AGIPGAAAAA GAAAAAAAVG ASGGDELQAL NQAFKEQMSG LDLSMPTLKR 1920
ERSDDYQDDL ELEGGGHNLS DNESLEGQEP EDKTTDYEKV LHKSALAAAA AYMSNAVRSS 1980
RRKPAAPQWV NPAGAVTNPS AVVAAVAAAA AAAADNERII NGVCVMQASE YGRDDTDSNK 2040
PTDGGNDSDH EHAQLEIDQR FMEPEVHIKQ EEDDDEEQSG SVNLDNEDNA TSEQKLKVIN 2100
EEKLRMVRVR RLSSTGGGSS EEMPAPLAPP PPPPAASSSI VSGESTTSSS SSSNTSSSTP 2160
AVTTAAATAA AGWNY
2176Fasta Sequence
>P10180|ct|Drosophila melanogaster(Fruit fly)
MQPTLPQAAGTADMDLTAVQSINDWFFKKEQIYLLAQFWQQRATLAEKEVNTLKEQLSTGNPDSNLNSENSDTAAAAATAAAVAAVVAGATATNDIEDEQQQQLQQTASGGILESDSDKLLNSSIVAAAITLQQQNGSNLLANTNTPSPSPPLLSAEQQQQLQSSLQQSGGVGGACLNPKLFFNHAQQMMMMEAAAAAAAAALQQQQQQQSPLHSPANEVAIPTEQPAATVATGAAAAAAAAATPIATGNVKSGSTTSNANHTNSNNSHQDEEELDDEEEDEEEDEDEDDEEENASMQSNADDMELDAQQETRTEPSATTQQQHQQQDTEDLEENKDAGEASLNVSNNHNTTDSNNSCSRKNNNGGNESEQHVASSAEDDDCANNNTNTSNNNNTSNTATSNTNNNNNNNSSSGNSEKRKKKNNNNNNGQPAVLLAAKDKEIKALLDELQRLRAQEQTHLVQIQRLEEHLEVKRQHIIRLEARLDKQQINEALAEATALSAAASTNNNNNSQSSDNNKKLNTAAERPMDASSNADLPESTKAPVPAEDDEEDEDQAMLVDSEEAEDKPEDSHHDDDEDEDEDREAVNATTTDSNELKIKKEQHSPLDLNVLSPNSAIAAAAAAAAAAACANDPNKFQALLIERTKALAAEALKNGASDALSEDAHHQQQQHHQQQHQHQQQHHQQQHLHQQHHHHLQQQPNSGSNSNPASNDHHHGHHLHGHGLLHPSSAHHLHHQTTESNSNSSTPTAAGNNNGSNNSSSNTNANSTAQLAASLASTLNGTKSLMQEDSNGLAAVAMAAHAQHAAALGPGFLPGLPAFQFAAAQVAAGGDGRGHYRFADSELQLPPGASMAGRLGESLIPKGDPMEAKLQEMLRYNMDKYANQALDTLHISRRVRELLSVHNIGQRLFAKYILGLSQGTVSELLSKPKPWDKLTEKGRDSYRKMHAWACDDNAVMLLKSLIPKKDSGLPQYAGRGAGGAGGDDSMSEDRIAHILSEASSLMKQSSVAQHREQERRSHGGEDSHSNEDSKSPPQSCTSPFFKVENQLKQHQHLNPEQAAAQQREREREQREREQQQRLRHDDQDKMARLYQELIARTPRETAFPSFLFSPSLFGGAAGMPGAASNAFPAMADENMRHVFEREIAKLQQHQQQQQAAQAQAQFPNFSSLMALQQQVLNGAQDLSLAAAAAKDIKLNGQRSSLEHSAGSSSCSKDGERDDAYPSSLHGRKSEGGGTPAPPAPPSGPGTGAGAPPTAAPPTGGASSNSAAPSPLSNSILPPALSSQGEEFAATASPLQRMASITNSLITQPPVTPHHSTPQRPTKAVLPPITQQQFDMFNNLNTEDIVRRVKEALSQYSISQRLFGESVLGLSQGSVSDLLARPKPWHMLTQKGREPFIRMKMFLEDENAVHKLVASQYKIAPEKLMRTGSYSGSPQMPQGLASKMQAASLPMQKMMSELKLQEPAQAQHLMQQMQAAAMSAAMQQQQVAQAQQQAQQAQQAQQHLQQQAQQHLQQQQHLAQQQHPHQQHHQAAAAAAALHHQSMLLTSPGLPPQHAISLPPSAGGAQPGGPGGNQGSSNPSNSEKKPMLMPVHGTNAMRSLHQHMSPTVYEMAALTQDLDTHDITTKIKEALLANNIGQKIFGEAVLGLSQGSVSELLSKPKPWHMLSIKGREPFIRMQLWLSDANNVERLQLLKNERREASKRRRSTGPNQQDNSSDTSSNDTNDFYTSSPGPGSVGSGVGGAPPSKKQRVLFSEEQKEALRLAFALDPYPNVGTIEFLANELGLATRTITNWFHNHRMRLKQQVPHGPAGQDNPIPSRESTSATPFDPVQFRILLQQRLLELHKERMGMSGAPIPYPPYFAAAAILGRSLAGIPGAAAAAGAAAAAAAVGASGGDELQALNQAFKEQMSGLDLSMPTLKRERSDDYQDDLELEGGGHNLSDNESLEGQEPEDKTTDYEKVLHKSALAAAAAYMSNAVRSSRRKPAAPQWVNPAGAVTNPSAVVAAVAAAAAAAADNERIINGVCVMQASEYGRDDTDSNKPTDGGNDSDHEHAQLEIDQRFMEPEVHIKQEEDDDEEQSGSVNLDNEDNATSEQKLKVINEEKLRMVRVRRLSSTGGGSSEEMPAPLAPPPPPPAASSSIVSGESTTSSSSSSNTSSSTPAVTTAAATAAAGWNY
|
| Keyword |
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0217--Developmental protein
KW-0238--DNA-binding
KW-0371--Homeobox
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
KW-0804--Transcription
KW-0805--Transcription regulation
|
| Interpro |
IPR003350--CUT_dom
IPR017970--Homeobox_CS
IPR001356--Homeobox_dom
IPR009057--Homeodomain-like
IPR010982--Lambda_DNA-bd_dom
|
| PROSITE |
PS51042--CUT
PS00027--HOMEOBOX_1
PS50071--HOMEOBOX_2
|
| Pfam |
PF02376--CUT
PF00046--Homeobox
|
| Gene Ontology |
GO:0005634--C:nucleus
GO:0003677--F:DNA binding
GO:0000976--F:transcription regulatory region sequence-specific DNA binding
GO:0007469--P:antennal development
GO:0048098--P:antennal joint development
GO:0007417--P:central nervous system development
GO:0070983--P:dendrite guidance
GO:0048813--P:dendrite morphogenesis
GO:0008585--P:female gonad development
GO:0060288--P:formation of a compartment boundary
GO:0008587--P:imaginal disc-derived wing margin morphogenesis
GO:0061332--P:Malpighian tubule bud morphogenesis
GO:0007443--P:Malpighian tubule morphogenesis
GO:0000278--P:mitotic cell cycle
GO:0045746--P:negative regulation of Notch signaling pathway
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0048477--P:oogenesis
GO:0007424--P:open tracheal system development
GO:0030707--P:ovarian follicle cell development
GO:0030713--P:ovarian follicle cell stalk formation
GO:0007422--P:peripheral nervous system development
GO:0006355--P:regulation of transcription, DNA-templated
GO:0007605--P:sensory perception of sound
GO:0035277--P:spiracle morphogenesis, open tracheal system
GO:0006351--P:transcription, DNA-templated
|
