dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0005250
Uniprot Accession P0CX80; MTCU1_YEAST; D3DL02; P07215;
Genbank Protein ID NP_011920.1; NP_011922.1;
Genbank Nucleotide ID NM_001179183.1; NM_001179185.1;
Protein Name Copper metallothionein 1-1
Protein Synonyms/Alias
Gene Name CUP1-1
Gene Synonyms/Alias MTH1;YHR053C;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)
Protects the cell against copper toxicity by tightly chelating copper ions. May also act as a depository for copper designated for the effective transfer into the apo forms of copper proteins.
Phosphorylation Sites
dbPAF PTMs: 2
PositionPeptidesSourceReferences ( PMIDs )
33EQCQKSCSCPTGCNSPhosphoPep 2.019060867
36QKSCSCPTGCNSDDKPhosphoGRID 2.0;curated19779198; 22817900
Sequence
(Fasta)
MFSELINFQN EGHECQCQCG SCKNNEQCQK SCSCPTGCNS DDKCPCGNKS EETKKSCCSG 60
K 62
Keyword

KW-0002--3D-structure
KW-0181--Complete proteome
KW-0186--Copper
KW-0903--Direct protein sequencing
KW-0479--Metal-binding
KW-0480--Metal-thiolate cluster
KW-1185--Reference proteome

Interpro

IPR017854--Metalthion_dom
IPR022710--Metalthion_dom_yeast

PROSITE
Pfam

PF11403--Yeast_MT

Gene Ontology

GO:0005829--C:cytosol
GO:0016209--F:antioxidant activity
GO:0046870--F:cadmium ion binding
GO:0005507--F:copper ion binding
GO:0004784--F:superoxide dismutase activity
GO:0071585--P:detoxification of cadmium ion
GO:0010273--P:detoxification of copper ion
GO:0019430--P:removal of superoxide radicals
GO:0046688--P:response to copper ion