dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0005203
Uniprot Accession P0CX20; YRF11_YEAST; D6VTG2; O94087; P24088; P24089; Q53WX0; Q99313;
Genbank Protein ID NP_010834.1; NP_013572.3; NP_061495.4;
Genbank Nucleotide ID NM_001180853.1; NM_001182355.3; NM_001184447.3;
Protein Name Y' element ATP-dependent helicase protein 1 copy 1
Protein Synonyms/Alias
Gene Name YRF1-1
Gene Synonyms/Alias YDR545W;D3703.4;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)
Catalyzes DNA unwinding and is involved in telomerase-independent telomere maintenance.
Phosphorylation Sites
dbPAF PTMs: 2
PositionPeptidesSourceReferences ( PMIDs )
749VAGEAASSDHDQKISPhosphoPep 2.0;curated19060867; 22369663
756SDHDQKISRVTRKRPPhosphoPep 2.019060867
Sequence
(Fasta)
MKVSDRRKFE KANFDEFESA LNNKNDLVHC PSITLFESIP TEVRSFYEDE KSGLIKVVKF 60
RTGAMDRKRS FEKIVISVMV GKNVQKFLTF VEDEPDFQGG PIPSKYLIPK KINLMVYTLF 120
QVHTLKFNRK DYDTLSLFYL NRGYYNELSF RVLERCHEIA SARPNDSSTM RTFTDFVSGA 180
PIVRSLQKST IRKYGYNLAP YMFLLLHVDE LSIFSAYQAS LPGEKKVDTE RLKRDLCPRK 240
PIEIKYFSQI CNDMMNKKDR LGDILHIILR ACALNFGAGP RGGAGDEEDR SITNEEPIIP 300
SVDEHGLKVC KLRSPNTPRR LRKTLDAVKA LLVSSCACTA RDLDIFDDTN GVAMWKWIKI 360
LYHEVAQETT LKDSYRITLV PSSDGISVCG KLFNREYVRG FYFACKAQFD NLWGELNNCF 420
YMPTVVDIAS LILRNREVLF REPKRGIDEY LENDSFLQMI PVKYREIVLP KLRRDTNKMT 480
AALKNKVTVA IDELTVPLMW MVHFAVGYPY RYPELQLLAF AGPQRNVYVD DTTRRIQLYT 540
DYNKNGSSEP RLKTLDGLTS DYVFYFVTVL RQMQICALGN SYDAFNHDPW MDVVGFEDPD 600
QVTNRDISRI VLYSYMFLNT AKGCLVEYAT FRQYMRELPK NAPQKLNFRE MRQGLIALGR 660
HCVGSRFETD LYESATSELM ANHSVQTGRN IYGVDSFSLT SVSGTTATLL QERASERWIQ 720
WLGLESDYHC SFSSTRNAED VVAGEAASSD HDQKISRVTR KRPREPKSTN DILVAGQKLF 780
GSSFEFRDLH QLRLCHEIYM ADTPSVAVQA PPGYGKTELF HLPLIALASK GDVKYVSFLF 840
VPYTVLLANC MIRLSRCGCL NVAPVRNFIE EGCDGVTDLY VGIYDDLAST NFTDRIAAWE 900
NIVECTFRTN NVKLGYLIVD EFHNFETEVY RQSQFGGITN LDFDAFEKAI FLSGTAPEAV 960
ADAALQRIGL TGLAKKSMDI NELKRSEDLS RGLSSYPTRM FNLIKEKSEV PLGHVHKIWK 1020
KVESQPEEAL KLLLALFEIE PESKAIVVAS TTNEVEELAC SWRKYFRVVW IHGKLGAAEK 1080
VSRTKEFVTD GSMRVLIGTK LVTEGIDIKQ LMMVIMLDNR LNIIELIQGV GRLRDGGLCY 1140
LLSRKNSWAA RNRKGELPPI KEGCITEQVR EFYGLESKKG KKGQHVGCCG SRTDLSADTV 1200
ELIERMDRLA EKQATASMSI IALPSSFQES NSSDRCRKYC SSDEDSDTCI HGSANASTNA 1260
TTNSSTNATT TASTNVRTSA TTTASINVRT SAITTESTNS STNATTTAST NVRTSATTTA 1320
SINVRTSATT TESTNSNTSA TTTESTDSNT SATTTESTDS NTSATTTAST NSSTNATTTA 1380
STNSSTNATT TESTNASAKE DANKDGNAED NRFHPVTDIN KESYKRKGSQ MVLLERKKLK 1440
AQFPNTSENM NVLQFLGFRS DEIKHLFLYG IDVYFCPEGV FTQYGLCKGC QKMFELCVCW 1500
AGQKVSYRRM AWEALAVERM LRNDEEYKEY LEDIEPYHGD PVGYLKYFSV KRGEIYSQIQ 1560
RNYAWYLAIT RRRETISVLD STRGKQGSQV FRMSGRQIKE LYYKVWSNLR ESKTEVLQYF 1620
LNWDEKKCRE EWEAKDDTVF VEALEKVGVF QRLRSMTSAG LQGPQYVKLQ FSRHHRQLRS 1680
RYELSLGMHL RDQLALGVTP SKVPHWTAFL SMLIGLFYNK TFRQKLEYLL EQISEVWLLP 1740
HWLDLANVEV LAADNTRVPL YMLMVAVHKE LDSDDVPDGR FDIILLCRDS SREVGE 1797
Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0347--Helicase
KW-0378--Hydrolase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011545--DEAD/DEAH_box_helicase_dom
IPR014001--Helicase_ATP-bd
IPR001650--Helicase_C
IPR027417--P-loop_NTPase

PROSITE

PS51192--HELICASE_ATP_BIND_1
PS51194--HELICASE_CTER

Pfam

PF00270--DEAD
PF00271--Helicase_C

Gene Ontology

GO:0005634--C:nucleus
GO:0005524--F:ATP binding
GO:0003678--F:DNA helicase activity
GO:0003676--F:nucleic acid binding
GO:0032508--P:DNA duplex unwinding
GO:0000722--P:telomere maintenance via recombination