dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0005049
Uniprot Accession P0C2J4; YL21A_YEAST; D6VZ46;
Genbank Protein ID NP_058175.1;
Genbank Nucleotide ID NM_001184410.1;
Protein Name Transposon Ty2-LR1 Gag polyprotein
Protein Synonyms/Alias
Gene Name TY2A-LR1
Gene Synonyms/Alias YLRWTy2-1 GAG;YLR410W-A;L9931.7b;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)		 Capsid protein (CA) is the structural component of the virus-like particle (VLP), forming the shell that encapsulates the retrotransposons dimeric RNA genome. The particles are assembled from trimer-clustered units and there are holes in the capsid shells that allow for the diffusion of macromolecules. CA has also nucleocapsid-like chaperone activity, promoting primer tRNA(i)-Met annealing to the multipartite primer-binding site (PBS), dimerization of Ty2 RNA and initiation of reverse transcription (By similarity).
Phosphorylation Sites
 dbPAF PTMs: 6
PositionPeptidesSourceReferences ( PMIDs )
406IATSSKFSRVNNDHIcurated19823750
419HINESTVSSQYLSDDcurated19823750
422ESTVSSQYLSDDNELPhosphoPep 2.0;curated19060867; 26040406; 19823750
424TVSSQYLSDDNELSLPhosphoGRID 2.0;PhosphoPep 2.0;SysPTM 2.0;curated17330950; 19060867; 15665377; 19366988; 26040406; 26040289;
430LSDDNELSLRPATERPhosphoGRID 2.0;curated17330950; 26040289
435ELSLRPATERI----curated19823750; 23825934
Sequence
(Fasta)		MESQQLHQNP HSLHGSAYAS VTSKEVPSNQ DPLAVSASNL PEFDRDSTKV NSQQETTPGT 60
SAVPENHHHV SPQPASVPPP QNGQYQQHGM MTPNKAMASN WAHYQQPSMM TCSHYQTSPA 120
YYQPDPHYPL PQYIPPLSTS SPDPIDLKNQ HSEIPQAKTK VGNNVLPPHT LTSEENFSTW 180
VKFYIRFLKN SNLGDIIPND QGEIKRQMTY EEHAYIYNTF QAFAPFHLLP TWVKQILEIN 240
YADILTVLCK SVSKMQTNNQ ELKDWIALAN LEYDGSTSAD TFEITVSTII QRLKENNINV 300
SDRLACQLIL KGLSGDFKYL RNQYRTKTNM KLSQLFAEIQ LIYDENKIMN LNKPSQYKQH 360
SEYKNVSRTS PNTTNTKVTT RNYHRTNSSK PRAAKAHNIA TSSKFSRVNN DHINESTVSS 420
QYLSDDNELS LRPATERI 439
Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-1185--Reference proteome
KW-0688--Ribosomal frameshifting
KW-0694--RNA-binding
KW-0814--Transposable element
Interpro

IPR015820--Retrotransposon_Ty1A_N
PROSITE
Pfam

PF01021--TYA
Gene Ontology

GO:0005737--C:cytoplasm
GO:0000943--C:retrotransposon nucleocapsid
GO:0003723--F:RNA binding
GO:0032197--P:transposition, RNA-mediated