dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0005019
Uniprot Accession P0C0V8; RS21A_YEAST; D6VXB8; P05760;
Genbank Protein ID NP_012983.3;
Genbank Nucleotide ID NM_001179847.3;
Protein Name 40S ribosomal protein S21-A
Protein Synonyms/Alias S26;YS25;
Gene Name RPS21A
Gene Synonyms/Alias RPS25;RPS25A;RPS26A;YKR057W;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)		 Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Has a physiological role leading to 18S rRNA stability.
Phosphorylation Sites
 dbPAF PTMs: 8
PositionPeptidesSourceReferences ( PMIDs )
18LYVPRKCSATNRIIKcurated19823750
31IKADDHASVQINVAKcurated24961812
61ALSGYVRSRGESDDSPhosphoPep 2.019060867
65YVRSRGESDDSLNRLPhosphoGRID 2.0;PHOSIDA;PhosphoPep 2.0;SysPTM 2.0;curated21177495; 18407956; 17563356; 21081558; 19060867; 19366988;
68SRGESDDSLNRLAQNPhosphoGRID 2.0;PhosphoPep 2.0;SysPTM 2.0;curated21177495; 19060867; 18407956; 19366988; 22369663; 22817900
84GLLKNVWSYSR----dbPTM 3.0;PhosphoGRID 2.0;PhosphoPep 2.0;SysPTM 2.0;curated15665377; 16381945; 23193290; 19060867; 19366988; 18407956;
85LLKNVWSYSR-----PhosphoGRID 2.0;curated21177495; 20377248
86LKNVWSYSR------PhosphoGRID 2.0;PhosphoPep 2.0;SysPTM 2.0;curated18407956; 19823750; 19779198; 19795423; 19060867; 19366988;
Sequence
(Fasta)		MENDKGQLVE LYVPRKCSAT NRIIKADDHA SVQINVAKVD EEGRAIPGEY VTYALSGYVR 60
SRGESDDSLN RLAQNDGLLK NVWSYSR 88
Keyword

KW-0002--3D-structure
KW-0007--Acetylation
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0903--Direct protein sequencing
KW-1185--Reference proteome
KW-0687--Ribonucleoprotein
KW-0689--Ribosomal protein
KW-0698--rRNA processing
Interpro

IPR001931--Ribosomal_S21e
IPR018279--Ribosomal_S21e_CS
PROSITE

PS00996--RIBOSOMAL_S21E
Pfam

PF01249--Ribosomal_S21e
Gene Ontology

GO:0022627--C:cytosolic small ribosomal subunit
GO:0003735--F:structural constituent of ribosome
GO:0002181--P:cytoplasmic translation
GO:0000447--P:endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5
8S rRNA an-- LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5
8S rRNA, L--U-rRNA)
GO:0000461--P:endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5
8S rRNA, L--U-rRNA)
GO:0042274--P:ribosomal small subunit biogenesis