dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0004965
Uniprot Accession P09734; TBA3_YEAST; D6W0G1;
Genbank Protein ID NP_013582.1;
Genbank Nucleotide ID NM_001182487.1;
Protein Name Tubulin alpha-3 chain
Protein Synonyms/Alias
Gene Name TUB3
Gene Synonyms/Alias YML124C;YM7056.02C;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)
Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.
Phosphorylation Sites
dbPAF PTMs: 1
PositionPeptidesSourceReferences ( PMIDs )
440YIEVGADSYAEEF--PHOSIDA;curated21081558; 19795423
Sequence
(Fasta)
MREVISINVG QAGCQIGNAC WELYSLEHGI KEDGHLEDGL SKPKGGEEGF STFFHETGYG 60
KFVPRAIYVD LEPNVIDEVR TGRFKELFHP EQLINGKEDA ANNYARGHYT VGREIVDEVE 120
ERIRKMADQC DGLQGFLFTH SLGGGTGSGL GSLLLENLSY EYGKKSKLEF AVYPAPQLST 180
SVVEPYNTVL TTHTTLEHAD CTFMVDNEAI YDICKRNLGI SRPSFSNLNG LIAQVISSVT 240
ASLRFDGSLN VDLNEFQTNL VPYPRIHFPL VSYAPILSKK RATHESNSVS EITNACFEPG 300
NQMVKCDPTK GKYMANCLLY RGDVVTRDVQ RAVEQVKNKK TVQMVDWCPT GFKIGICYEP 360
PSVIPSSELA NVDRAVCMLS NTTAIADAWK RIDQKFDLMY AKRAFVHWYV GEGMEEGEFT 420
EAREDLAALE RDYIEVGADS YAEEF 446
Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0206--Cytoskeleton
KW-0342--GTP-binding
KW-0493--Microtubule
KW-0547--Nucleotide-binding
KW-1185--Reference proteome

Interpro

IPR002452--Alpha_tubulin
IPR008280--Tub_FtsZ_C
IPR000217--Tubulin
IPR018316--Tubulin/FtsZ_2-layer-sand-dom
IPR023123--Tubulin_C
IPR017975--Tubulin_CS
IPR003008--Tubulin_FtsZ_GTPase

PROSITE

PS00227--TUBULIN

Pfam

PF00091--Tubulin
PF03953--Tubulin_C

Gene Ontology

GO:0005881--C:cytoplasmic microtubule
GO:0005828--C:kinetochore microtubule
GO:0005880--C:nuclear microtubule
GO:0005816--C:spindle pole body
GO:0045298--C:tubulin complex
GO:0005525--F:GTP binding
GO:0003924--F:GTPase activity
GO:0005200--F:structural constituent of cytoskeleton
GO:0045143--P:homologous chromosome segregation
GO:0000070--P:mitotic sister chromatid segregation
GO:0030473--P:nuclear migration along microtubule
GO:0051258--P:protein polymerization