Tag |
Content |
dbPAF ID |
dbPAF-0004965 |
Uniprot Accession |
P09734; TBA3_YEAST; D6W0G1; |
Genbank Protein ID |
NP_013582.1; |
Genbank Nucleotide ID |
NM_001182487.1; |
Protein Name |
Tubulin alpha-3 chain |
Protein Synonyms/Alias |
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Gene Name |
TUB3 |
Gene Synonyms/Alias |
YML124C;YM7056.02C; |
Organism |
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast) |
NCBI Taxa ID |
559292 |
Functional Description (View all) |
Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.Functional Description
Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.
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Phosphorylation Sites
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dbPAF PTMs: 1 Position | Peptides | Source | References ( PMIDs ) |
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440 | YIEVGADSYAEEF-- | PHOSIDA;curated | 21081558; 19795423 |
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Sequence (Fasta) | MREVISINVG QAGCQIGNAC WELYSLEHGI KEDGHLEDGL SKPKGGEEGF STFFHETGYG 60 KFVPRAIYVD LEPNVIDEVR TGRFKELFHP EQLINGKEDA ANNYARGHYT VGREIVDEVE 120 ERIRKMADQC DGLQGFLFTH SLGGGTGSGL GSLLLENLSY EYGKKSKLEF AVYPAPQLST 180 SVVEPYNTVL TTHTTLEHAD CTFMVDNEAI YDICKRNLGI SRPSFSNLNG LIAQVISSVT 240 ASLRFDGSLN VDLNEFQTNL VPYPRIHFPL VSYAPILSKK RATHESNSVS EITNACFEPG 300 NQMVKCDPTK GKYMANCLLY RGDVVTRDVQ RAVEQVKNKK TVQMVDWCPT GFKIGICYEP 360 PSVIPSSELA NVDRAVCMLS NTTAIADAWK RIDQKFDLMY AKRAFVHWYV GEGMEEGEFT 420 EAREDLAALE RDYIEVGADS YAEEF
446Fasta Sequence
>P09734|TUB3|Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast) MREVISINVGQAGCQIGNACWELYSLEHGIKEDGHLEDGLSKPKGGEEGFSTFFHETGYGKFVPRAIYVDLEPNVIDEVRTGRFKELFHPEQLINGKEDAANNYARGHYTVGREIVDEVEERIRKMADQCDGLQGFLFTHSLGGGTGSGLGSLLLENLSYEYGKKSKLEFAVYPAPQLSTSVVEPYNTVLTTHTTLEHADCTFMVDNEAIYDICKRNLGISRPSFSNLNGLIAQVISSVTASLRFDGSLNVDLNEFQTNLVPYPRIHFPLVSYAPILSKKRATHESNSVSEITNACFEPGNQMVKCDPTKGKYMANCLLYRGDVVTRDVQRAVEQVKNKKTVQMVDWCPTGFKIGICYEPPSVIPSSELANVDRAVCMLSNTTAIADAWKRIDQKFDLMYAKRAFVHWYVGEGMEEGEFTEAREDLAALERDYIEVGADSYAEEF
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Keyword |
KW-0181--Complete proteome KW-0963--Cytoplasm KW-0206--Cytoskeleton KW-0342--GTP-binding KW-0493--Microtubule KW-0547--Nucleotide-binding KW-1185--Reference proteome
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Interpro |
IPR002452--Alpha_tubulin IPR008280--Tub_FtsZ_C IPR000217--Tubulin IPR018316--Tubulin/FtsZ_2-layer-sand-dom IPR023123--Tubulin_C IPR017975--Tubulin_CS IPR003008--Tubulin_FtsZ_GTPase
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PROSITE |
PS00227--TUBULIN
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Pfam |
PF00091--Tubulin PF03953--Tubulin_C
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Gene Ontology |
GO:0005881--C:cytoplasmic microtubule GO:0005828--C:kinetochore microtubule GO:0005880--C:nuclear microtubule GO:0005816--C:spindle pole body GO:0045298--C:tubulin complex GO:0005525--F:GTP binding GO:0003924--F:GTPase activity GO:0005200--F:structural constituent of cytoskeleton GO:0045143--P:homologous chromosome segregation GO:0000070--P:mitotic sister chromatid segregation GO:0030473--P:nuclear migration along microtubule GO:0051258--P:protein polymerization
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