| Tag |
Content |
| dbPAF ID |
dbPAF-0004964 |
| Uniprot Accession |
P09733; TBA1_YEAST; D6W0J8;
|
| Genbank Protein ID |
NP_013625.1;
|
| Genbank Nucleotide ID |
NM_001182444.1;
|
| Protein Name |
Tubulin alpha-1 chain |
| Protein Synonyms/Alias |
|
| Gene Name |
TUB1 |
| Gene Synonyms/Alias |
YML085C; |
| Organism |
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast) |
| NCBI Taxa ID |
559292 |
Functional Description
(View all) |
Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.Functional Description
Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. |
Phosphorylation Sites
|
dbPAF PTMs: 2 |
Sequence
(Fasta) | MREVISINVG QAGCQIGNAC WELYSLEHGI KPDGHLEDGL SKPKGGEEGF STFFHETGYG 60
KFVPRAIYVD LEPNVIDEVR NGPYKDLFHP EQLISGKEDA ANNYARGHYT VGREILGDVL 120
DRIRKLADQC DGLQGFLFTH SLGGGTGSGL GSLLLEELSA EYGKKSKLEF AVYPAPQVST 180
SVVEPYNTVL TTHTTLEHAD CTFMVDNEAI YDMCKRNLDI PRPSFANLNN LIAQVVSSVT 240
ASLRFDGSLN VDLNEFQTNL VPYPRIHFPL VSYSPVLSKS KAFHESNSVS EITNACFEPG 300
NQMVKCDPRD GKYMATCLLY RGDVVTRDVQ RAVEQVKNKK TVQLVDWCPT GFKIGICYEP 360
PTATPNSQLA TVDRAVCMLS NTTSIAEAWK RIDRKFDLMY AKRAFVHWYV GEGMEEGEFT 420
EAREDLAALE RDYIEVGADS YAEEEEF
448Fasta Sequence
>P09733|TUB1|Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
MREVISINVGQAGCQIGNACWELYSLEHGIKPDGHLEDGLSKPKGGEEGFSTFFHETGYGKFVPRAIYVDLEPNVIDEVRNGPYKDLFHPEQLISGKEDAANNYARGHYTVGREILGDVLDRIRKLADQCDGLQGFLFTHSLGGGTGSGLGSLLLEELSAEYGKKSKLEFAVYPAPQVSTSVVEPYNTVLTTHTTLEHADCTFMVDNEAIYDMCKRNLDIPRPSFANLNNLIAQVVSSVTASLRFDGSLNVDLNEFQTNLVPYPRIHFPLVSYSPVLSKSKAFHESNSVSEITNACFEPGNQMVKCDPRDGKYMATCLLYRGDVVTRDVQRAVEQVKNKKTVQLVDWCPTGFKIGICYEPPTATPNSQLATVDRAVCMLSNTTSIAEAWKRIDRKFDLMYAKRAFVHWYVGEGMEEGEFTEAREDLAALERDYIEVGADSYAEEEEF
|
| Keyword |
KW-0002--3D-structure
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0206--Cytoskeleton
KW-0342--GTP-binding
KW-0493--Microtubule
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
|
| Interpro |
IPR002452--Alpha_tubulin
IPR008280--Tub_FtsZ_C
IPR000217--Tubulin
IPR018316--Tubulin/FtsZ_2-layer-sand-dom
IPR023123--Tubulin_C
IPR017975--Tubulin_CS
IPR003008--Tubulin_FtsZ_GTPase
|
| PROSITE |
PS00227--TUBULIN
|
| Pfam |
PF00091--Tubulin
PF03953--Tubulin_C
|
| Gene Ontology |
GO:0005881--C:cytoplasmic microtubule
GO:0005828--C:kinetochore microtubule
GO:0005880--C:nuclear microtubule
GO:0034399--C:nuclear periphery
GO:0005827--C:polar microtubule
GO:0005816--C:spindle pole body
GO:0045298--C:tubulin complex
GO:0005525--F:GTP binding
GO:0003924--F:GTPase activity
GO:0005200--F:structural constituent of cytoskeleton
GO:0045143--P:homologous chromosome segregation
GO:0000070--P:mitotic sister chromatid segregation
GO:0030473--P:nuclear migration along microtubule
GO:0051258--P:protein polymerization
|
