dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0004914
Uniprot Accession P09436; SYIC_YEAST; D6VPS6;
Genbank Protein ID NP_009477.1;
Genbank Nucleotide ID NM_001178316.1;
Protein Name Isoleucine--tRNA ligase, cytoplasmic
Protein Synonyms/Alias Isoleucyl-tRNA synthetase;IleRS;
Gene Name ILS1
Gene Synonyms/Alias YBL076C;YBL0734;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)
Phosphorylation Sites
 dbPAF PTMs: 17
PositionPeptidesSourceReferences ( PMIDs )
2------MSESNAHFScurated22369663; 19823750; 24961812
50FDGPPFATGTPHYGHcurated20377248
52GPPFATGTPHYGHILcurated20377248
186PYSTGLTTPLSNFEAdbPTM 3.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 19366988
274KKPKNEKYKIVEKIKcurated22817900
404SYPFCWRSDTPLLYRPhosphoGRID 2.021126336
406PFCWRSDTPLLYRSVdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 19779198; 19366988; 22369663;
412DTPLLYRSVPAWFVRPhosphoGRID 2.0;curated19779198; 22817900
604AADGRKMSKSLKNYPcurated24961812
614LKNYPDPSIVLNKYGcurated25315811
632LRLYLINSPVLKAESPhosphoGRID 2.0;curated19779198; 26040289; 22817900; 24961812
802KYGKDGRSVHFLSYPcurated19823750
807GRSVHFLSYPVVKKEcurated19823750
808RSVHFLSYPVVKKEYcurated19823750
829TAVSRMQSVIDLGRNdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;UniProt;curated18407956; 16381945; 23193290; 21126336; 19366988; 22369663;
920KVKDALPSVTSEQVRcurated25315811
1059PIGDEEQSINDTIFKdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;UniProt;curated17563356; 18407956; 16381945; 23193290; 21126336; 19779198;
Sequence
(Fasta)		MSESNAHFSF PKEEEKVLSL WDEIDAFHTS LELTKDKPEF SFFDGPPFAT GTPHYGHILA 60
STIKDIVPRY ATMTGHHVER RFGWDTHGVP IEHIIDKKLG ITGKDDVFKY GLENYNNECR 120
SIVMTYASDW RKTIGRLGRW IDFDNDYKTM YPSFMESTWW AFKQLHEKGQ VYRGFKVMPY 180
STGLTTPLSN FEAQQNYKDV NDPAVTIGFN VIGQEKTQLV AWTTTPWTLP SNLSLCVNAD 240
FEYVKIYDET RDRYFILLES LIKTLYKKPK NEKYKIVEKI KGSDLVGLKY EPLFPYFAEQ 300
FHETAFRVIS DDYVTSDSGT GIVHNAPAFG EEDNAACLKN GVISEDSVLP NAIDDLGRFT 360
KDVPDFEGVY VKDADKLIIK YLTNTGNLLL ASQIRHSYPF CWRSDTPLLY RSVPAWFVRV 420
KNIVPQMLDS VMKSHWVPNT IKEKRFANWI ANARDWNVSR NRYWGTPIPL WVSDDFEEVV 480
CVGSIKELEE LTGVRNITDL HRDVIDKLTI PSKQGKGDLK RIEEVFDCWF ESGSMPYASQ 540
HYPFENTEKF DERVPANFIS EGLDQTRGWF YTLAVLGTHL FGSVPYKNVI VSGIVLAADG 600
RKMSKSLKNY PDPSIVLNKY GADALRLYLI NSPVLKAESL KFKEEGVKEV VSKVLLPWWN 660
SFKFLDGQIA LLKKMSNIDF QYDDSVKSDN VMDRWILASM QSLVQFIHEE MGQYKLYTVV 720
PKLLNFIDEL TNWYIRFNRR RLKGENGVED CLKALNSLFD ALFTFVRAMA PFTPFLSESI 780
YLRLKEYIPE AVLAKYGKDG RSVHFLSYPV VKKEYFDEAI ETAVSRMQSV IDLGRNIREK 840
KTISLKTPLK TLVILHSDES YLKDVEALKN YIIEELNVRD VVITSDEAKY GVEYKAVADW 900
PVLGKKLKKD AKKVKDALPS VTSEQVREYL ESGKLEVAGI ELVKGDLNAI RGLPESAVQA 960
GQETRTDQDV LIIMDTNIYS ELKSEGLARE LVNRIQKLRK KCGLEATDDV LVEYELVKDT 1020
IDFEAIVKEH FDMLSKTCRS DIAKYDGSKT DPIGDEEQSI NDTIFKLKVF KL 1073
Keyword

KW-0030--Aminoacyl-tRNA synthetase
KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0903--Direct protein sequencing
KW-0436--Ligase
KW-0547--Nucleotide-binding
KW-0597--Phosphoprotein
KW-0648--Protein biosynthesis
KW-1185--Reference proteome
Interpro

IPR001412--aa-tRNA-synth_I_CS
IPR002300--aa-tRNA-synth_Ia
IPR002301--Ile-tRNA-ligase
IPR023586--Ile-tRNA-ligase_type2
IPR013155--M/V/L/I-tRNA-synth_anticd-bd
IPR014729--Rossmann-like_a/b/a_fold
IPR009080--tRNAsynth_1a_anticodon-bd
IPR009008--Val/Leu/Ile-tRNA-synth_edit
PROSITE

PS00178--AA_TRNA_LIGASE_I
Pfam

PF08264--Anticodon_1
PF00133--tRNA-synt_1
Gene Ontology

GO:0005829--C:cytosol
GO:0002161--F:aminoacyl-tRNA editing activity
GO:0005524--F:ATP binding
GO:0004822--F:isoleucine-tRNA ligase activity
GO:0006428--P:isoleucyl-tRNA aminoacylation