dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0004837
Uniprot Accession P08928; LAM0_DROME; Q9VMQ0;
Genbank Protein ID NP_001245892.1; NP_001245893.1; NP_001285629.1; NP_476616.1;
Genbank Nucleotide ID NM_001258963.2; NM_001258964.2; NM_001298700.1; NM_057268.5;
Protein Name Lamin Dm0
Protein Synonyms/Alias
Gene Name Lam
Gene Synonyms/Alias CG6944;
Organism Drosophila melanogaster(Fruit fly)
NCBI Taxa ID 7227
Functional Description
(View all)		 Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin.
Phosphorylation Sites
 dbPAF PTMs: 35 (View all)
PositionPeptidesSourceReferences ( PMIDs )
10SKSRRAGTATPQPGNdbPTM 3.0;Phospho.ELM 9.0;UniProt;curated18327897; 16381945; 23193290; 3126192; 22817900
12SRRAGTATPQPGNTSdbPTM 3.0;Phospho.ELM 9.0;UniProt;curated18327897; 16381945; 23193290; 3126192; 22817900
18ATPQPGNTSTPRPPScurated22817900
20PQPGNTSTPRPPSAGdbPTM 3.0;Phospho.ELM 9.0;PhosphoPep 2.0;UniProt;curated18327897; 16381945; 23193290; 19060867; 3126192; 22817900
25TSTPRPPSAGPQPPPdbPTM 3.0;Phospho.ELM 9.0;PHOSIDA;PhosphoPep 2.0;UniProt;curated18327897; 16381945; 23193290; 8537453; 21081558; 19060867; 3
34GPQPPPPSTHSQTASdbPTM 3.0;Phospho.ELM 9.0;PhosphoPep 2.0;UniProt18327897; 16381945; 23193290; 19060867; 3126192
37PPPPSTHSQTASSPLcurated22817900
39PPSTHSQTASSPLSPdbPTM 3.0;Phospho.ELM 9.0;UniProt;curated18327897; 16381945; 23193290; 3126192; 22817900
41STHSQTASSPLSPTRdbPTM 3.0;Phospho.ELM 9.0;UniProt18327897; 16381945; 23193290; 3126192
42THSQTASSPLSPTRHdbPTM 3.0;Phospho.ELM 9.0;UniProt;curated18327897; 16381945; 23193290; 9013881; 3126192; 22817900
45QTASSPLSPTRHSRVdbPTM 3.0;Phospho.ELM 9.0;PhosphoPep 2.0;UniProt;curated18327897; 16381945; 23193290; 19060867; 3126192; 22817900
47ASSPLSPTRHSRVAEdbPTM 3.0;Phospho.ELM 9.0;UniProt18327897; 16381945; 23193290; 3126192
50PLSPTRHSRVAEKVEdbPTM 3.0;Phospho.ELM 9.09013881; 16381945; 23193290
235SFKDQIHSQEINESRdbPTM 3.0;Phospho.ELM 9.0;PHOSIDA;UniProt;curated18327897; 16381945; 23193290; 21081558; 3126192; 22817900
249RRIKQTEYSEIDGRLdbPTM 3.0;Phospho.ELM 9.0;UniProt18327897; 16381945; 23193290; 3126192
250RIKQTEYSEIDGRLSdbPTM 3.0;Phospho.ELM 9.0;UniProt;curated18327897; 16381945; 23193290; 3126192; 22817900
267YDAKLKQSLQELRAQPHOSIDA;curated21081558; 22817900
311TSNSTHKSIEELRSTdbPTM 3.0;Phospho.ELM 9.0;UniProt18327897; 16381945; 23193290; 3126192
413EEARLNITPATNTATdbPTM 3.0;Phospho.ELM 9.0;PhosphoPep 2.0;UniProt18327897; 16381945; 23193290; 19060867; 3126192
418NITPATNTATVQSFSPhosphoPep 2.019060867
Sequence
(Fasta)		MSSKSRRAGT ATPQPGNTST PRPPSAGPQP PPPSTHSQTA SSPLSPTRHS RVAEKVELQN 60
LNDRLATYID RVRNLETENS RLTIEVQTTR DTVTRETTNI KNIFEAELLE TRRLLDDTAR 120
DRARAEIDIK RLWEENEELK NKLDKKTKEC TTAEGNVRMY ESRANELNNK YNQANADRKK 180
LNEDLNEALK ELERLRKQFE ETRKNLEQET LSRVDLENTI QSLREELSFK DQIHSQEINE 240
SRRIKQTEYS EIDGRLSSEY DAKLKQSLQE LRAQYEEQMQ INRDEIQSLY EDKIQRLQEA 300
AARTSNSTHK SIEELRSTRV RIDALNANIN ELEQANADLN ARIRDLERQL DNDRERHGQE 360
IDLLEKELIR LREEMTQQLK EYQDLMDIKV SLDLEIAAYD KLLVGEEARL NITPATNTAT 420
VQSFSQSLRN STRATPSRRT PSAAVKRKRA VVDESEDHSV ADYYVSASAK GNVEIKEIDP 480
EGKFVRLFNK GSEEVAIGGW QLQRLINEKG PSTTYKFHRS VRIEPNGVIT VWSADTKASH 540
EPPSSLVMKS QKWVSADNTR TILLNSEGEA VANLDRIKRI VSQHTSSSRL SRRRSVTAVD 600
GNEQLYHQQG DPQQSNEKCA IM 623
Keyword

KW-0007--Acetylation
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0403--Intermediate filament
KW-0449--Lipoprotein
KW-0488--Methylation
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-0636--Prenylation
KW-1185--Reference proteome
Interpro

IPR001664--IF
IPR001322--Lamin_tail_dom
PROSITE
Pfam

PF00038--Filament
PF00932--LTD
Gene Ontology

GO:0005813--C:centrosome
GO:0005638--C:lamin filament
GO:0005811--C:lipid particle
GO:0005875--C:microtubule associated complex
GO:0072686--C:mitotic spindle
GO:0005635--C:nuclear envelope
GO:0005637--C:nuclear inner membrane
GO:0005652--C:nuclear lamina
GO:0005634--C:nucleus
GO:0005102--F:receptor binding
GO:0005198--F:structural molecule activity
GO:0008344--P:adult locomotory behavior
GO:0007569--P:cell aging
GO:0007417--P:central nervous system development
GO:0051297--P:centrosome organization
GO:0040003--P:chitin-based cuticle development
GO:0006342--P:chromatin silencing
GO:0001745--P:compound eye morphogenesis
GO:0048546--P:digestive tract morphogenesis
GO:0035262--P:gonad morphogenesis
GO:0070870--P:heterochromatin maintenance involved in chromatin silencing
GO:0046331--P:lateral inhibition
GO:0007084--P:mitotic nuclear envelope reassembly
GO:0008285--P:negative regulation of cell proliferation
GO:0050777--P:negative regulation of immune response
GO:0006998--P:nuclear envelope organization
GO:0071763--P:nuclear membrane organization
GO:0007097--P:nuclear migration
GO:0031081--P:nuclear pore distribution
GO:0006997--P:nucleus organization
GO:0090435--P:protein localization to nuclear envelope
GO:0007283--P:spermatogenesis
GO:0007430--P:terminal branching, open tracheal system