| Tag |
Content |
| dbPAF ID |
dbPAF-0004825 |
| Uniprot Accession |
P08879; NDKA_DROME; Q9V9U5;
|
| Genbank Protein ID |
NP_001287624.1; NP_001287625.1; NP_476761.3;
|
| Genbank Nucleotide ID |
NM_001300695.1; NM_001300696.1; NM_057413.4;
|
| Protein Name |
Nucleoside diphosphate kinase |
| Protein Synonyms/Alias |
|
| Gene Name |
awd |
| Gene Synonyms/Alias |
K-pn;CG2210; |
| Organism |
Drosophila melanogaster(Fruit fly) |
| NCBI Taxa ID |
7227 |
Functional Description
(View all) |
Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.Functional Description
Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. |
Phosphorylation Sites
|
dbPAF PTMs: 4 |
Sequence
(Fasta) | MAANKERTFI MVKPDGVQRG LVGKIIERFE QKGFKLVALK FTWASKELLE KHYADLSARP 60
FFPGLVNYMN SGPVVPMVWE GLNVVKTGRQ MLGATNPADS LPGTIRGDFC IQVGRNIIHG 120
SDAVESAEKE IALWFNEKEL VTWTPAAKDW IYE
154Fasta Sequence
>P08879|awd|Drosophila melanogaster(Fruit fly)
MAANKERTFIMVKPDGVQRGLVGKIIERFEQKGFKLVALKFTWASKELLEKHYADLSARPFFPGLVNYMNSGPVVPMVWEGLNVVKTGRQMLGATNPADSLPGTIRGDFCIQVGRNIIHGSDAVESAEKEIALWFNEKELVTWTPAAKDWIYE
|
| Keyword |
KW-0002--3D-structure
KW-0007--Acetylation
KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0206--Cytoskeleton
KW-0903--Direct protein sequencing
KW-0418--Kinase
KW-0460--Magnesium
KW-0479--Metal-binding
KW-0493--Microtubule
KW-0546--Nucleotide metabolism
KW-0547--Nucleotide-binding
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0808--Transferase
|
| Interpro |
IPR001564--Nucleoside_diP_kinase
IPR023005--Nucleoside_diP_kinase_AS
|
| PROSITE |
PS00469--NDP_KINASES
|
| Pfam |
PF00334--NDK
|
| Gene Ontology |
GO:0005829--C:cytosol
GO:0005622--C:intracellular
GO:0005874--C:microtubule
GO:0005875--C:microtubule associated complex
GO:0005880--C:nuclear microtubule
GO:0005886--C:plasma membrane
GO:0005524--F:ATP binding
GO:0005525--F:GTP binding
GO:0016301--F:kinase activity
GO:0000287--F:magnesium ion binding
GO:0008017--F:microtubule binding
GO:0004550--F:nucleoside diphosphate kinase activity
GO:0034332--P:adherens junction organization
GO:0006241--P:CTP biosynthetic process
GO:0007427--P:epithelial cell migration, open tracheal system
GO:0016334--P:establishment or maintenance of polarity of follicular epithelium
GO:0006183--P:GTP biosynthetic process
GO:0007017--P:microtubule-based process
GO:0007067--P:mitotic nuclear division
GO:0006165--P:nucleoside diphosphate phosphorylation
GO:0009142--P:nucleoside triphosphate biosynthetic process
GO:0009117--P:nucleotide metabolic process
GO:0007424--P:open tracheal system development
GO:0018105--P:peptidyl-serine phosphorylation
GO:0046777--P:protein autophosphorylation
GO:0006468--P:protein phosphorylation
GO:0006163--P:purine nucleotide metabolic process
GO:0006220--P:pyrimidine nucleotide metabolic process
GO:0042981--P:regulation of apoptotic process
GO:0035152--P:regulation of tube architecture, open tracheal system
GO:0006228--P:UTP biosynthetic process
|
