Tag |
Content |
dbPAF ID |
dbPAF-0004822 |
Uniprot Accession |
P08841; TBB3_DROME; Q6I8M0; Q6I8M1; Q9W184; |
Genbank Protein ID |
NP_523842.2; |
Genbank Nucleotide ID |
NM_079118.3; |
Protein Name |
Tubulin beta-3 chain |
Protein Synonyms/Alias |
Beta-3-tubulin; |
Gene Name |
betaTub60D |
Gene Synonyms/Alias |
TubB60C;CG3401; |
Organism |
Drosophila melanogaster(Fruit fly) |
NCBI Taxa ID |
7227 |
Functional Description (View all) |
Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.Functional Description
Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.
|
Phosphorylation Sites
|
dbPAF PTMs: 4 Position | Peptides | Source | References ( PMIDs ) |
---|
280 | MPGFAPLTSRGSQQY | PHOSIDA | 21081558 | 328 | AVFRGRMSMKEVDEQ | curated | 22817900 | 344 | LAVQNKNSSYFVEWI | PhosphoPep 2.0 | 19060867 | 345 | AVQNKNSSYFVEWIP | PhosphoPep 2.0 | 19060867 |
|
Sequence (Fasta) | MREIVNLQAG QCGNQIGAKF WEIISEEHGI DSNGIYVGDS DLQLERVSVY YNEASAVTRS 60 SGGKYVPRAI LLDLEPGTME SVRSGPYGQL FRPDNFVYGQ SGAGNNWAKG HYTEGAELVD 120 NVLDVVRKEC ENCDCLQGFQ LTHSLGGGTG SGMGTLLISK IREEYPDRIM NTYSVVPSPK 180 VSDTVVEPYN ATLSIHQLVE NTDETYCIDN EALYDICFRT LKVSNPSYGD LNHLVSLTMS 240 GVTTCLRFPG QLNADLRKLA VNMVPFPRLH FFMPGFAPLT SRGSQQYRAL TVPELTQQMF 300 DAKNMMAACD PRHGRYLTVA AVFRGRMSMK EVDEQMLAVQ NKNSSYFVEW IPNNVKTAVC 360 DIPPKGLKMS STFIGNTTAI QELFKRISEQ FSAMFRRKAF LHWYTGEGMD EMEFTEAESN 420 MNDLVSEYQQ YQEATADDEF DPEVNQEEVE GDCI
455Fasta Sequence
>P08841|betaTub60D|Drosophila melanogaster(Fruit fly) MREIVNLQAGQCGNQIGAKFWEIISEEHGIDSNGIYVGDSDLQLERVSVYYNEASAVTRSSGGKYVPRAILLDLEPGTMESVRSGPYGQLFRPDNFVYGQSGAGNNWAKGHYTEGAELVDNVLDVVRKECENCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTYSVVPSPKVSDTVVEPYNATLSIHQLVENTDETYCIDNEALYDICFRTLKVSNPSYGDLNHLVSLTMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAVFRGRMSMKEVDEQMLAVQNKNSSYFVEWIPNNVKTAVCDIPPKGLKMSSTFIGNTTAIQELFKRISEQFSAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQEATADDEFDPEVNQEEVEGDCI
|
Keyword |
KW-0181--Complete proteome KW-0963--Cytoplasm KW-0206--Cytoskeleton KW-0342--GTP-binding KW-0493--Microtubule KW-0547--Nucleotide-binding KW-1185--Reference proteome
|
Interpro |
IPR013838--Beta-tubulin_BS IPR002453--Beta_tubulin IPR008280--Tub_FtsZ_C IPR000217--Tubulin IPR018316--Tubulin/FtsZ_2-layer-sand-dom IPR023123--Tubulin_C IPR017975--Tubulin_CS IPR003008--Tubulin_FtsZ_GTPase
|
PROSITE |
PS00227--TUBULIN PS00228--TUBULIN_B_AUTOREG
|
Pfam |
PF00091--Tubulin PF03953--Tubulin_C
|
Gene Ontology |
GO:0005737--C:cytoplasm GO:0005874--C:microtubule GO:0005525--F:GTP binding GO:0003924--F:GTPase activity GO:0005200--F:structural constituent of cytoskeleton GO:0007411--P:axon guidance GO:0007409--P:axonogenesis GO:0007507--P:heart development GO:0030537--P:larval behavior GO:0007017--P:microtubule-based process GO:0022008--P:neurogenesis GO:0051258--P:protein polymerization GO:0009416--P:response to light stimulus
|