dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0004822
Uniprot Accession P08841; TBB3_DROME; Q6I8M0; Q6I8M1; Q9W184;
Genbank Protein ID NP_523842.2;
Genbank Nucleotide ID NM_079118.3;
Protein Name Tubulin beta-3 chain
Protein Synonyms/Alias Beta-3-tubulin;
Gene Name betaTub60D
Gene Synonyms/Alias TubB60C;CG3401;
Organism Drosophila melanogaster(Fruit fly)
NCBI Taxa ID 7227
Functional Description
(View all)
Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.
Phosphorylation Sites
dbPAF PTMs: 4
PositionPeptidesSourceReferences ( PMIDs )
280MPGFAPLTSRGSQQYPHOSIDA21081558
328AVFRGRMSMKEVDEQcurated22817900
344LAVQNKNSSYFVEWIPhosphoPep 2.019060867
345AVQNKNSSYFVEWIPPhosphoPep 2.019060867
Sequence
(Fasta)
MREIVNLQAG QCGNQIGAKF WEIISEEHGI DSNGIYVGDS DLQLERVSVY YNEASAVTRS 60
SGGKYVPRAI LLDLEPGTME SVRSGPYGQL FRPDNFVYGQ SGAGNNWAKG HYTEGAELVD 120
NVLDVVRKEC ENCDCLQGFQ LTHSLGGGTG SGMGTLLISK IREEYPDRIM NTYSVVPSPK 180
VSDTVVEPYN ATLSIHQLVE NTDETYCIDN EALYDICFRT LKVSNPSYGD LNHLVSLTMS 240
GVTTCLRFPG QLNADLRKLA VNMVPFPRLH FFMPGFAPLT SRGSQQYRAL TVPELTQQMF 300
DAKNMMAACD PRHGRYLTVA AVFRGRMSMK EVDEQMLAVQ NKNSSYFVEW IPNNVKTAVC 360
DIPPKGLKMS STFIGNTTAI QELFKRISEQ FSAMFRRKAF LHWYTGEGMD EMEFTEAESN 420
MNDLVSEYQQ YQEATADDEF DPEVNQEEVE GDCI 455
Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0206--Cytoskeleton
KW-0342--GTP-binding
KW-0493--Microtubule
KW-0547--Nucleotide-binding
KW-1185--Reference proteome

Interpro

IPR013838--Beta-tubulin_BS
IPR002453--Beta_tubulin
IPR008280--Tub_FtsZ_C
IPR000217--Tubulin
IPR018316--Tubulin/FtsZ_2-layer-sand-dom
IPR023123--Tubulin_C
IPR017975--Tubulin_CS
IPR003008--Tubulin_FtsZ_GTPase

PROSITE

PS00227--TUBULIN
PS00228--TUBULIN_B_AUTOREG

Pfam

PF00091--Tubulin
PF03953--Tubulin_C

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005874--C:microtubule
GO:0005525--F:GTP binding
GO:0003924--F:GTPase activity
GO:0005200--F:structural constituent of cytoskeleton
GO:0007411--P:axon guidance
GO:0007409--P:axonogenesis
GO:0007507--P:heart development
GO:0030537--P:larval behavior
GO:0007017--P:microtubule-based process
GO:0022008--P:neurogenesis
GO:0051258--P:protein polymerization
GO:0009416--P:response to light stimulus