dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0004818
Uniprot Accession P08761; MSRA_DROME; Q86NL3; Q8IQM6; Q8IT52; Q9VUP3; Q9VUP4; Q9VUP5;
Genbank Protein ID NP_524085.2; NP_730047.1;
Genbank Nucleotide ID NM_079361.3; NM_168622.2;
Protein Name Peptide methionine sulfoxide reductase
Protein Synonyms/Alias Ecdysone-induced protein 28/29 kDa;Methionine-S-sulfoxide reductase;Peptide-methionine (S)-S-oxide reductase;
Gene Name Eip71CD
Gene Synonyms/Alias Eip28/29;MsrA;CG7266;
Organism Drosophila melanogaster(Fruit fly)
NCBI Taxa ID 7227
Functional Description
(View all)
Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
Phosphorylation Sites
dbPAF PTMs: 1
PositionPeptidesSourceReferences ( PMIDs )
30EQKELNISPVHDVNVcurated22817900
Sequence
(Fasta)
MSLTITSSVT HPELKDLSTV RNEQKELNIS PVHDVNVTKA TATFGMGCFW GAESLYGATR 60
GVLRTTVGYA GGSSDLPTYR KMGDHTEVLE IDYDPTVISF KELLDLFWNN HEYGLTTPIK 120
RQYASLILYH DEEQKQVAHA SKLEEQERRA PEIITTEIAS KENFYPAEAY HQKYRLQGHK 180
DLASSLNLSP KLLQTSYVAT KLNGYLAGVG GIEQFKAEAE TMGLTPTQRQ YCYYHVEQNE 240
GQGLYC 247
Keyword

KW-0025--Alternative splicing
KW-0181--Complete proteome
KW-0560--Oxidoreductase
KW-1185--Reference proteome

Interpro

IPR028427--Met_Sox_Rdtase
IPR002569--Met_Sox_Rdtase_MsrA

PROSITE
Pfam

PF01625--PMSR

Gene Ontology

GO:0008113--F:peptide-methionine (S)-S-oxide reductase activity
GO:0048102--P:autophagic cell death
GO:0034599--P:cellular response to oxidative stress
GO:0008340--P:determination of adult lifespan
GO:0048812--P:neuron projection morphogenesis
GO:0030091--P:protein repair
GO:0006979--P:response to oxidative stress
GO:0035071--P:salivary gland cell autophagic cell death
GO:0000096--P:sulfur amino acid metabolic process