Tag |
Content |
dbPAF ID |
dbPAF-0004813 |
Uniprot Accession |
P08736; EF1A1_DROME; Q0E9B9; Q9V631; |
Genbank Protein ID |
NP_001286321.1; NP_001286322.1; NP_477375.1; NP_725085.1; |
Genbank Nucleotide ID |
NM_001299392.1; NM_001299393.1; NM_058027.5; NM_165850.3; |
Protein Name |
Elongation factor 1-alpha 1 |
Protein Synonyms/Alias |
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Gene Name |
Ef1alpha48D |
Gene Synonyms/Alias |
EF1B;F1;CG8280; |
Organism |
Drosophila melanogaster(Fruit fly) |
NCBI Taxa ID |
7227 |
Functional Description (View all) |
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.Functional Description
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
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Phosphorylation Sites
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dbPAF PTMs: 5 Position | Peptides | Source | References ( PMIDs ) |
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269 | VPVGRVETGVLKPGT | PhosphoPep 2.0 | 19060867 | 276 | TGVLKPGTVVVFAPA | PhosphoPep 2.0 | 19060867 | 286 | VFAPANITTEVKSVE | PhosphoPep 2.0 | 19060867 | 383 | KEKVDRRSGKTTEEN | PhosphoPep 2.0 | 19060867 | 386 | VDRRSGKTTEENPKF | PhosphoPep 2.0 | 19060867 |
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Sequence (Fasta) | MGKEKIHINI VVIGHVDSGK STTTGHLIYK CGGIDKRTIE KFEKEAQEMG KGSFKYAWVL 60 DKLKAERERG ITIDIALWKF ETAKYYVTII DAPGHRDFIK NMITGTSQAD CAVLIVAAGT 120 GEFEAGISKN GQTREHALLA FTLGVKQLIV GVNKMDSSEP PYSEARYEEI KKEVSSYIKK 180 IGYNPAAVAF VPISGWHGDN MLEPSTNMPW FKGWKVERKE GNADGKTLID ALDAILPPAR 240 PTDKALRLPL QDVYKIGGIG TVPVGRVETG VLKPGTVVVF APANITTEVK SVEMHHEALQ 300 EAVPGDNVGF NVKNVSVKEL RRGYVAGDSK ANPPKGAADF TAQVIVLNHP GQIANGYTPV 360 LDCHTAHIAC KFAEIKEKVD RRSGKTTEEN PKFIKSGDAA IVNLVPSKPL CVEAFQEFPP 420 LGRFAVRDMR QTVAVGVIKA VNFKDASGGK VTKAAEKATK GKK
464Fasta Sequence
>P08736|Ef1alpha48D|Drosophila melanogaster(Fruit fly) MGKEKIHINIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAQEMGKGSFKYAWVLDKLKAERERGITIDIALWKFETAKYYVTIIDAPGHRDFIKNMITGTSQADCAVLIVAAGTGEFEAGISKNGQTREHALLAFTLGVKQLIVGVNKMDSSEPPYSEARYEEIKKEVSSYIKKIGYNPAAVAFVPISGWHGDNMLEPSTNMPWFKGWKVERKEGNADGKTLIDALDAILPPARPTDKALRLPLQDVYKIGGIGTVPVGRVETGVLKPGTVVVFAPANITTEVKSVEMHHEALQEAVPGDNVGFNVKNVSVKELRRGYVAGDSKANPPKGAADFTAQVIVLNHPGQIANGYTPVLDCHTAHIACKFAEIKEKVDRRSGKTTEENPKFIKSGDAAIVNLVPSKPLCVEAFQEFPPLGRFAVRDMRQTVAVGVIKAVNFKDASGGKVTKAAEKATKGKK
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Keyword |
KW-0181--Complete proteome KW-0963--Cytoplasm KW-0903--Direct protein sequencing KW-0251--Elongation factor KW-0342--GTP-binding KW-0547--Nucleotide-binding KW-0597--Phosphoprotein KW-0648--Protein biosynthesis KW-1185--Reference proteome
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Interpro |
IPR031157--G_TR_CS IPR027417--P-loop_NTPase IPR000795--TF_GTP-bd_dom IPR009000--Transl_B-barrel IPR009001--Transl_elong_EF1A/Init_IF2_C IPR004539--Transl_elong_EF1A_euk/arc IPR004161--Transl_elong_EFTu/EF1A_2 IPR004160--Transl_elong_EFTu/EF1A_C
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PROSITE |
PS00301--G_TR_1 PS51722--G_TR_2
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Pfam |
PF03144--GTP_EFTU_D2 PF03143--GTP_EFTU_D3
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Gene Ontology |
GO:0005829--C:cytosol GO:0005853--C:eukaryotic translation elongation factor 1 complex GO:0005811--C:lipid particle GO:0005875--C:microtubule associated complex GO:0005525--F:GTP binding GO:0003924--F:GTPase activity GO:0003746--F:translation elongation factor activity GO:0008340--P:determination of adult lifespan GO:0006414--P:translational elongation
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