dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0004813
Uniprot Accession P08736; EF1A1_DROME; Q0E9B9; Q9V631;
Genbank Protein ID NP_001286321.1; NP_001286322.1; NP_477375.1; NP_725085.1;
Genbank Nucleotide ID NM_001299392.1; NM_001299393.1; NM_058027.5; NM_165850.3;
Protein Name Elongation factor 1-alpha 1
Protein Synonyms/Alias
Gene Name Ef1alpha48D
Gene Synonyms/Alias EF1B;F1;CG8280;
Organism Drosophila melanogaster(Fruit fly)
NCBI Taxa ID 7227
Functional Description
(View all)
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
Phosphorylation Sites
dbPAF PTMs: 5
PositionPeptidesSourceReferences ( PMIDs )
269VPVGRVETGVLKPGTPhosphoPep 2.019060867
276TGVLKPGTVVVFAPAPhosphoPep 2.019060867
286VFAPANITTEVKSVEPhosphoPep 2.019060867
383KEKVDRRSGKTTEENPhosphoPep 2.019060867
386VDRRSGKTTEENPKFPhosphoPep 2.019060867
Sequence
(Fasta)
MGKEKIHINI VVIGHVDSGK STTTGHLIYK CGGIDKRTIE KFEKEAQEMG KGSFKYAWVL 60
DKLKAERERG ITIDIALWKF ETAKYYVTII DAPGHRDFIK NMITGTSQAD CAVLIVAAGT 120
GEFEAGISKN GQTREHALLA FTLGVKQLIV GVNKMDSSEP PYSEARYEEI KKEVSSYIKK 180
IGYNPAAVAF VPISGWHGDN MLEPSTNMPW FKGWKVERKE GNADGKTLID ALDAILPPAR 240
PTDKALRLPL QDVYKIGGIG TVPVGRVETG VLKPGTVVVF APANITTEVK SVEMHHEALQ 300
EAVPGDNVGF NVKNVSVKEL RRGYVAGDSK ANPPKGAADF TAQVIVLNHP GQIANGYTPV 360
LDCHTAHIAC KFAEIKEKVD RRSGKTTEEN PKFIKSGDAA IVNLVPSKPL CVEAFQEFPP 420
LGRFAVRDMR QTVAVGVIKA VNFKDASGGK VTKAAEKATK GKK 464
Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0903--Direct protein sequencing
KW-0251--Elongation factor
KW-0342--GTP-binding
KW-0547--Nucleotide-binding
KW-0597--Phosphoprotein
KW-0648--Protein biosynthesis
KW-1185--Reference proteome

Interpro

IPR031157--G_TR_CS
IPR027417--P-loop_NTPase
IPR000795--TF_GTP-bd_dom
IPR009000--Transl_B-barrel
IPR009001--Transl_elong_EF1A/Init_IF2_C
IPR004539--Transl_elong_EF1A_euk/arc
IPR004161--Transl_elong_EFTu/EF1A_2
IPR004160--Transl_elong_EFTu/EF1A_C

PROSITE

PS00301--G_TR_1
PS51722--G_TR_2

Pfam

PF03144--GTP_EFTU_D2
PF03143--GTP_EFTU_D3

Gene Ontology

GO:0005829--C:cytosol
GO:0005853--C:eukaryotic translation elongation factor 1 complex
GO:0005811--C:lipid particle
GO:0005875--C:microtubule associated complex
GO:0005525--F:GTP binding
GO:0003924--F:GTPase activity
GO:0003746--F:translation elongation factor activity
GO:0008340--P:determination of adult lifespan
GO:0006414--P:translational elongation