| Tag |
Content |
| dbPAF ID |
dbPAF-0004796 |
| Uniprot Accession |
P08638; LEUR_YEAST; D6VZ85;
|
| Genbank Protein ID |
NP_013556.3;
|
| Genbank Nucleotide ID |
NM_001182339.3;
|
| Protein Name |
Regulatory protein LEU3 |
| Protein Synonyms/Alias |
|
| Gene Name |
LEU3 |
| Gene Synonyms/Alias |
YLR451W;L9324.1; |
| Organism |
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast) |
| NCBI Taxa ID |
559292 |
Functional Description
(View all) |
Factor for control of RNA levels of a group of leucine-specific genes.Functional Description
Factor for control of RNA levels of a group of leucine-specific genes. |
Phosphorylation Sites
|
dbPAF PTMs: 5 |
Sequence
(Fasta) | MEGRSDFVAT SQSGSEMSHS ETRNRTGMNA RKRKFACVEC RQQKSKCDAH ERAPEPCTKC 60
AKKNVPCILK RDFRRTYKRA RNEAIEKRFK ELTRTLTNLT SDEILKKIEE EQEIVLDNSN 120
FTKEKVKQLR KSAFETTEIE PRSYKTLRGE PISYSTNRRH TDSSPLTLLS SSTNFDPVHS 180
TNVMTDDQLK CLPKSLGDVY LSSSDIAELF QEFATKYHQF LPVVDLSKGA ERIYHLSPCL 240
FWVILLIGLR RKFGATDLMT RLSVLVKSVL SEITISPIIR YTPSDKDEPV LNVASVYSVQ 300
AFLLYTFWPP LTSSLSADTS WNTIGTAMFQ ALRVGLNCAG FSKEYASANS ELVNEQIRTW 360
ICCNVVSQTV ASSFGFPAYV SFDYLVISSI RVPNSKSQVD IPNELRQMAQ IARFENQIVN 420
TMNSTPASVT GMVSQEEKQP LLHVLNQQLS QLEISLEENN LDDIRKFLLL VAKVHLLTYY 480
FTDVTSQSAG KSNGNIYEGS YSIMELDTSF ETKRGLVKVY NAAVNFLIHA NSMWEHDPTI 540
IKYFPGLFVL NIWQSACIIS KLIHSSLHSM LDVNSGKKAY NNAISLTFNA SVLKYDMAYR 600
SSGIMRSIWS LFANMYDAWK NDQKEGGGRL NNDFNLGITI KSRMSVNVFF DCLYILKEKC 660
GMAKLERETK VSTAYNVDEE EEEDEDEEGE EEEEEEELSS KVPENMDSQQ LRTRKFTNVR 720
HPEKKARKII ETIPLDPNPI NAGSTSSGSS LTTPNSQVAN TISYRGILNK MSPREQLNHA 780
NLDSSVSTDI KDTEAVNEPL PIGRNAEHPA NQPPLSITQM QENTLPATQA NSSLLETYPI 840
VQSNPVTTTI KESPNSIMAG WDNWESDMVW RDVDILMNEF AFNPKV
887Fasta Sequence
>P08638|LEU3|Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
MEGRSDFVATSQSGSEMSHSETRNRTGMNARKRKFACVECRQQKSKCDAHERAPEPCTKCAKKNVPCILKRDFRRTYKRARNEAIEKRFKELTRTLTNLTSDEILKKIEEEQEIVLDNSNFTKEKVKQLRKSAFETTEIEPRSYKTLRGEPISYSTNRRHTDSSPLTLLSSSTNFDPVHSTNVMTDDQLKCLPKSLGDVYLSSSDIAELFQEFATKYHQFLPVVDLSKGAERIYHLSPCLFWVILLIGLRRKFGATDLMTRLSVLVKSVLSEITISPIIRYTPSDKDEPVLNVASVYSVQAFLLYTFWPPLTSSLSADTSWNTIGTAMFQALRVGLNCAGFSKEYASANSELVNEQIRTWICCNVVSQTVASSFGFPAYVSFDYLVISSIRVPNSKSQVDIPNELRQMAQIARFENQIVNTMNSTPASVTGMVSQEEKQPLLHVLNQQLSQLEISLEENNLDDIRKFLLLVAKVHLLTYYFTDVTSQSAGKSNGNIYEGSYSIMELDTSFETKRGLVKVYNAAVNFLIHANSMWEHDPTIIKYFPGLFVLNIWQSACIISKLIHSSLHSMLDVNSGKKAYNNAISLTFNASVLKYDMAYRSSGIMRSIWSLFANMYDAWKNDQKEGGGRLNNDFNLGITIKSRMSVNVFFDCLYILKEKCGMAKLERETKVSTAYNVDEEEEEDEDEEGEEEEEEEELSSKVPENMDSQQLRTRKFTNVRHPEKKARKIIETIPLDPNPINAGSTSSGSSLTTPNSQVANTISYRGILNKMSPREQLNHANLDSSVSTDIKDTEAVNEPLPIGRNAEHPANQPPLSITQMQENTLPATQANSSLLETYPIVQSNPVTTTIKESPNSIMAGWDNWESDMVWRDVDILMNEFAFNPKV
|
| Keyword |
KW-0002--3D-structure
KW-0010--Activator
KW-0028--Amino-acid biosynthesis
KW-0100--Branched-chain amino acid biosynthesis
KW-0181--Complete proteome
KW-0238--DNA-binding
KW-0432--Leucine biosynthesis
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0862--Zinc
|
| Interpro |
IPR001138--Zn2-C6_fun-type_DNA-bd
|
| PROSITE |
PS00463--ZN2_CY6_FUNGAL_1
PS50048--ZN2_CY6_FUNGAL_2
|
| Pfam |
PF00172--Zn_clus
|
| Gene Ontology |
GO:0005634--C:nucleus
GO:0044212--F:transcription regulatory region DNA binding
GO:0001077--F:transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0001078--F:transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0008270--F:zinc ion binding
GO:0009098--P:leucine biosynthetic process
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:2001278--P:positive regulation of leucine biosynthetic process
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0006366--P:transcription from RNA polymerase II promoter
|
