| Tag |
Content |
| dbPAF ID |
dbPAF-0004793 |
| Uniprot Accession |
P08630; BTKL_DROME; A4V0F3; A4V0F4; O45032; O76132; O76133; P11361; Q6NNV0; Q8T0A0; Q9VLQ2; Q9VLQ3;
|
| Genbank Protein ID |
NP_001097120.1; NP_001097121.1; NP_476745.1; NP_476746.1; NP_723369.1; NP_723370.1;
|
| Genbank Nucleotide ID |
NM_001103650.2; NM_001103651.3; NM_057397.6; NM_057398.4; NM_164804.2; NM_164805.2;
|
| Protein Name |
Tyrosine-protein kinase Btk29A |
| Protein Synonyms/Alias |
Dsrc28C;Dsrc29a; |
| Gene Name |
Btk29A |
| Gene Synonyms/Alias |
Src2;Src29A;Tec29;CG8049; |
| Organism |
Drosophila melanogaster(Fruit fly) |
| NCBI Taxa ID |
7227 |
Functional Description
(View all) |
Required for proper ring canal development. Also required for the development of male genitalia and for adult survival.Functional Description
Required for proper ring canal development. Also required for the development of male genitalia and for adult survival. |
Phosphorylation Sites
|
dbPAF PTMs: 1 |
Sequence
(Fasta) | MMGTKHRNSH VNGSIKSSSS LRSSSKSFQA KMDLMSERLY DVVKSGSMVK RAQNKKRFTP 60
VNYKHRWFEL TKRTFSYFDV ENVERRRERG RIHLKGVRLV EEATVSGEGG DPFAPDGYPF 120
QVGYCEISAS ANSHQLENGN GGGSGVGIEG QQSGRAVPQY TLYVIANSEK ERSEWIRAIR 180
QVCEDSNTPK SYRYHPGLWS GKKWSCCKGL SRTTFGCRAA AHWREANNNP SNGSSPAQNS 240
TRSISPNSST TNSQFSLQHN SSGSLGGGVG GGLGGGGSLG LGGGGGGGGS CTPTSLQPQS 300
SLTTFKQSPT LLNGNGTLLD ANMPGGIPTP GTPNSKAKDN SHFVKLVVAL YPFKAIEGGD 360
LSLEKNAEYE VIDDSQEHWW KVKDALGNVG YIPSNYVKPK ALLGLERYEW YVGDMSRQRA 420
ESLLKQGDKE GCFVVRKSST KGLYTLSLHT KVPQSHVKHY HIKQNARCEY YLSEKHCCET 480
IPDLINYHRH NSGGLACRLK SSPCDRPVPP TAGLSHDKWE IHPMELMLME ELGSGQFGVV 540
RRGKWRGSID TAVKMMKEGT MSEDDFIEEA KVMTKLQHPN LVQLYGVCSK HRPIYIVTEY 600
MKHGSLLNYL RRHEKTLIGN MGLLLDMCIQ VSKGMTYLER HNYIHRDLAA RNCLVGSENV 660
VKVADFGLAR YVLDDQYTSS GGTKFPIKWA PPEVLNYTRF SSKSDVWAYG VLMWEIFTCG 720
KMPYGRLKNT EVVERVQRGI ILEKPKSCAK EIYDVMKLCW SHGPEERPAF RVLMDQLALV 780
AQTLTD
787Fasta Sequence
>P08630|Btk29A|Drosophila melanogaster(Fruit fly)
MMGTKHRNSHVNGSIKSSSSLRSSSKSFQAKMDLMSERLYDVVKSGSMVKRAQNKKRFTPVNYKHRWFELTKRTFSYFDVENVERRRERGRIHLKGVRLVEEATVSGEGGDPFAPDGYPFQVGYCEISASANSHQLENGNGGGSGVGIEGQQSGRAVPQYTLYVIANSEKERSEWIRAIRQVCEDSNTPKSYRYHPGLWSGKKWSCCKGLSRTTFGCRAAAHWREANNNPSNGSSPAQNSTRSISPNSSTTNSQFSLQHNSSGSLGGGVGGGLGGGGSLGLGGGGGGGGSCTPTSLQPQSSLTTFKQSPTLLNGNGTLLDANMPGGIPTPGTPNSKAKDNSHFVKLVVALYPFKAIEGGDLSLEKNAEYEVIDDSQEHWWKVKDALGNVGYIPSNYVKPKALLGLERYEWYVGDMSRQRAESLLKQGDKEGCFVVRKSSTKGLYTLSLHTKVPQSHVKHYHIKQNARCEYYLSEKHCCETIPDLINYHRHNSGGLACRLKSSPCDRPVPPTAGLSHDKWEIHPMELMLMEELGSGQFGVVRRGKWRGSIDTAVKMMKEGTMSEDDFIEEAKVMTKLQHPNLVQLYGVCSKHRPIYIVTEYMKHGSLLNYLRRHEKTLIGNMGLLLDMCIQVSKGMTYLERHNYIHRDLAARNCLVGSENVVKVADFGLARYVLDDQYTSSGGTKFPIKWAPPEVLNYTRFSSKSDVWAYGVLMWEIFTCGKMPYGRLKNTEVVERVQRGIILEKPKSCAKEIYDVMKLCWSHGPEERPAFRVLMDQLALVAQTLTD
|
| Keyword |
KW-0025--Alternative splicing
KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0479--Metal-binding
KW-0547--Nucleotide-binding
KW-0597--Phosphoprotein
KW-0656--Proto-oncogene
KW-1185--Reference proteome
KW-0727--SH2 domain
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase
KW-0862--Zinc
KW-0863--Zinc-finger
|
| Interpro |
IPR011009--Kinase-like_dom
IPR011993--PH/PTB_dom
IPR001849--PH_domain
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom
IPR001562--Znf_Btk_motif
|
| PROSITE |
PS50003--PH_DOMAIN
PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50001--SH2
PS50002--SH3
PS51113--ZF_BTK
|
| Pfam |
PF00779--BTK
PF00169--PH
PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1
|
| Gene Ontology |
GO:0045177--C:apical part of cell
GO:0071944--C:cell periphery
GO:0005737--C:cytoplasm
GO:0031234--C:extrinsic component of cytoplasmic side of plasma membrane
GO:0045172--C:germline ring canal
GO:0005886--C:plasma membrane
GO:0005524--F:ATP binding
GO:0046872--F:metal ion binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity
GO:0004713--F:protein tyrosine kinase activity
GO:0030036--P:actin cytoskeleton organization
GO:0030154--P:cell differentiation
GO:0007349--P:cellularization
GO:0007619--P:courtship behavior
GO:0008340--P:determination of adult lifespan
GO:0042023--P:DNA endoreduplication
GO:0007391--P:dorsal closure
GO:0007301--P:female germline ring canal formation
GO:0008258--P:head involution
GO:0007485--P:imaginal disc-derived male genitalia development
GO:0007476--P:imaginal disc-derived wing morphogenesis
GO:0045087--P:innate immune response
GO:0007254--P:JNK cascade
GO:0030717--P:karyosome formation
GO:0048477--P:oogenesis
GO:0007424--P:open tracheal system development
GO:0030723--P:ovarian fusome organization
GO:0007300--P:ovarian nurse cell to oocyte transport
GO:0038083--P:peptidyl-tyrosine autophosphorylation
GO:0018108--P:peptidyl-tyrosine phosphorylation
GO:0006468--P:protein phosphorylation
GO:0030833--P:regulation of actin filament polymerization
GO:0042127--P:regulation of cell proliferation
GO:0044719--P:regulation of imaginal disc-derived wing size
GO:0007435--P:salivary gland morphogenesis
GO:0046960--P:sensitization
GO:0035277--P:spiracle morphogenesis, open tracheal system
GO:0007169--P:transmembrane receptor protein tyrosine kinase signaling pathway
|
