| Tag |
Content |
| dbPAF ID |
dbPAF-0004771 |
| Uniprot Accession |
P08536; MET3_YEAST; D6VWI5; Q66R66;
|
| Genbank Protein ID |
NP_012543.3;
|
| Genbank Nucleotide ID |
NM_001181668.3;
|
| Protein Name |
Sulfate adenylyltransferase |
| Protein Synonyms/Alias |
ATP-sulfurylase;Methionine-requiring protein 3;Sulfate adenylate transferase;SAT; |
| Gene Name |
MET3 |
| Gene Synonyms/Alias |
YJR010W;J1436; |
| Organism |
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast) |
| NCBI Taxa ID |
559292 |
Functional Description
(View all) |
Catalyzes the first intracellular reaction of sulfate assimilation, forming adenosine-5'-phosphosulfate (APS) from inorganic sulfate and ATP. Plays an important role in sulfate activation as a component of the biosynthesis pathway of sulfur-containing amino acids.Functional Description
Catalyzes the first intracellular reaction of sulfate assimilation, forming adenosine-5'-phosphosulfate (APS) from inorganic sulfate and ATP. Plays an important role in sulfate activation as a component of the biosynthesis pathway of sulfur-containing amino acids. |
Phosphorylation Sites
|
dbPAF PTMs: 3 |
Sequence
(Fasta) | MPAPHGGILQ DLIARDALKK NELLSEAQSS DILVWNLTPR QLCDIELILN GGFSPLTGFL 60
NENDYSSVVT DSRLADGTLW TIPITLDVDE AFANQIKPDT RIALFQDDEI PIAILTVQDV 120
YKPNKTIEAE KVFRGDPEHP AISYLFNVAG DYYVGGSLEA IQLPQHYDYP GLRKTPAQLR 180
LEFQSRQWDR VVAFQTRNPM HRAHRELTVR AAREANAKVL IHPVVGLTKP GDIDHHTRVR 240
VYQEIIKRYP NGIAFLSLLP LAMRMSGDRE AVWHAIIRKN YGASHFIVGR DHAGPGKNSK 300
GVDFYGPYDA QELVESYKHE LDIEVVPFRM VTYLPDEDRY APIDQIDTTK TRTLNISGTE 360
LRRRLRVGGE IPEWFSYPEV VKILRESNPP RPKQGFSIVL GNSLTVSREQ LSIALLSTFL 420
QFGGGRYYKI FEHNNKTELL SLIQDFIGSG SGLIIPNQWE DDKDSVVGKQ NVYLLDTSSS 480
ADIQLESADE PISHIVQKVV LFLEDNGFFV F
512Fasta Sequence
>P08536|MET3|Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
MPAPHGGILQDLIARDALKKNELLSEAQSSDILVWNLTPRQLCDIELILNGGFSPLTGFLNENDYSSVVTDSRLADGTLWTIPITLDVDEAFANQIKPDTRIALFQDDEIPIAILTVQDVYKPNKTIEAEKVFRGDPEHPAISYLFNVAGDYYVGGSLEAIQLPQHYDYPGLRKTPAQLRLEFQSRQWDRVVAFQTRNPMHRAHRELTVRAAREANAKVLIHPVVGLTKPGDIDHHTRVRVYQEIIKRYPNGIAFLSLLPLAMRMSGDREAVWHAIIRKNYGASHFIVGRDHAGPGKNSKGVDFYGPYDAQELVESYKHELDIEVVPFRMVTYLPDEDRYAPIDQIDTTKTRTLNISGTELRRRLRVGGEIPEWFSYPEVVKILRESNPPRPKQGFSIVLGNSLTVSREQLSIALLSTFLQFGGGRYYKIFEHNNKTELLSLIQDFIGSGSGLIIPNQWEDDKDSVVGKQNVYLLDTSSSADIQLESADEPISHIVQKVVLFLEDNGFFVF
|
| Keyword |
KW-0002--3D-structure
KW-0028--Amino-acid biosynthesis
KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0198--Cysteine biosynthesis
KW-0963--Cytoplasm
KW-0486--Methionine biosynthesis
KW-0547--Nucleotide-binding
KW-0548--Nucleotidyltransferase
KW-1185--Reference proteome
KW-0808--Transferase
|
| Interpro |
IPR025980--ATP-Sase_PUA-like_dom
IPR027417--P-loop_NTPase
IPR015947--PUA-like_domain
IPR014729--Rossmann-like_a/b/a_fold
IPR027535--Sulf_adenylyltr_euk
IPR024951--Sulfurylase_cat_dom
IPR002650--Sulphate_adenylyltransferase
|
| PROSITE |
|
| Pfam |
PF01747--ATP-sulfurylase
PF14306--PUA_2
|
| Gene Ontology |
GO:0005737--C:cytoplasm
GO:0005524--F:ATP binding
GO:0004781--F:sulfate adenylyltransferase (ATP) activity
GO:0019344--P:cysteine biosynthetic process
GO:0070814--P:hydrogen sulfide biosynthetic process
GO:0009086--P:methionine biosynthetic process
GO:0019379--P:sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin)
GO:0000096--P:sulfur amino acid metabolic process
|
