dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0004770
Uniprot Accession P08524; FPPS_YEAST; D6VW20; P15495;
Genbank Protein ID NP_012368.1;
Genbank Nucleotide ID NM_001181600.1;
Protein Name Farnesyl pyrophosphate synthase
Protein Synonyms/Alias
Gene Name ERG20
Gene Synonyms/Alias BOT3;FDS1;FPP1;YJL167W;J0525;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)		 Catalyzes the sequential condensation of isopentenyl pyrophosphate with the allylic pyrophosphates, dimethylallyl pyrophosphate, and then with the resultant geranylpyrophosphate to the ultimate product farnesyl pyrophosphate.
Phosphorylation Sites
 dbPAF PTMs: 1
PositionPeptidesSourceReferences ( PMIDs )
317LYHEYEESIAKDLKAcurated24961812
Sequence
(Fasta)		MASEKEIRRE RFLNVFPKLV EELNASLLAY GMPKEACDWY AHSLNYNTPG GKLNRGLSVV 60
DTYAILSNKT VEQLGQEEYE KVAILGWCIE LLQAYFLVAD DMMDKSITRR GQPCWYKVPE 120
VGEIAINDAF MLEAAIYKLL KSHFRNEKYY IDITELFHEV TFQTELGQLM DLITAPEDKV 180
DLSKFSLKKH SFIVTFKTAY YSFYLPVALA MYVAGITDEK DLKQARDVLI PLGEYFQIQD 240
DYLDCFGTPE QIGKIGTDIQ DNKCSWVINK ALELASAEQR KTLDENYGKK DSVAEAKCKK 300
IFNDLKIEQL YHEYEESIAK DLKAKISQVD ESRGFKADVL TAFLNKVYKR SK 353
Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0414--Isoprene biosynthesis
KW-0444--Lipid biosynthesis
KW-0443--Lipid metabolism
KW-0460--Magnesium
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0808--Transferase
Interpro

IPR008949--Isoprenoid_synthase_dom
IPR000092--Polyprenyl_synt
PROSITE

PS00723--POLYPRENYL_SYNTHASE_1
PS00444--POLYPRENYL_SYNTHASE_2
Pfam

PF00348--polyprenyl_synt
Gene Ontology

GO:0005737--C:cytoplasm
GO:0005783--C:endoplasmic reticulum
GO:0004161--F:dimethylallyltranstransferase activity
GO:0004337--F:geranyltranstransferase activity
GO:0046872--F:metal ion binding
GO:0006696--P:ergosterol biosynthetic process
GO:0045337--P:farnesyl diphosphate biosynthetic process
GO:0033384--P:geranyl diphosphate biosynthetic process
GO:0008299--P:isoprenoid biosynthetic process