dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0004749
Uniprot Accession P08425; SYFM_YEAST; D6W455; Q12410;
Genbank Protein ID NP_015372.2;
Genbank Nucleotide ID NM_001184144.1;
Protein Name Phenylalanine--tRNA ligase, mitochondrial
Protein Synonyms/Alias Phenylalanyl-tRNA synthetase;PheRS;
Gene Name MSF1
Gene Synonyms/Alias YPR047W;YP9499.05;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)		 Is responsible for the charging of tRNA(Phe) with phenylalanine in mitochondrial translation.
Phosphorylation Sites
 dbPAF PTMs: 3
PositionPeptidesSourceReferences ( PMIDs )
260EVFNKKISSMIKNKAcurated22817900
261VFNKKISSMIKNKANcurated22817900
270IKNKANNTPKELKVRcurated22817900
Sequence
(Fasta)		MFLNRMMKTR TGLYRLYSTL KVPHVEINGI KYKTDPQTTN VTDSIIKLTD RSLHLKESHP 60
VGILRDLIEK KLNSVDNTFK IFNNFKPVVT TMENFDSLGF PKDHPGRSKS DTYYINETHL 120
LRTHTSAHEL ECFQKIRNDS DNIKSGFLIS ADVYRRDEID KTHYPVFHQM EGATIWKRTK 180
ADVGVKEPMY IEKIREDIRQ VENLLNKENV KITVDDDTIP LKENNPKQEY MSDLEVDLCS 240
QHLKRSIELI VSEVFNKKIS SMIKNKANNT PKELKVRWIN AYFPWTAPSW EIEVWWQGEW 300
LELCGCGLIR QDVLLRAGYK PSETIGWAFG LGLDRIAMLL FEIPDIRLLW SRDERFSRQF 360
SKGLITSFKP YSKHPGSFRD VAFWLPEDKP DIHQVHENDL MEIIRNIAGD LVESVKLVDS 420
FTHPKTGRKS MCYRINYQSM DRNLTNAEVN TLQDMVCSKL VKEYSVELR
Keyword

KW-0030--Aminoacyl-tRNA synthetase
KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0436--Ligase
KW-0496--Mitochondrion
KW-0547--Nucleotide-binding
KW-0648--Protein biosynthesis
KW-1185--Reference proteome
KW-0809--Transit peptide
Interpro

IPR006195--aa-tRNA-synth_II
IPR004530--Phe-tRNA-synth_IIc_mito
IPR002319--Phenylalanyl-tRNA_Synthase
IPR005121--PheS_beta_Fdx_antiC-bd
PROSITE

PS50862--AA_TRNA_LIGASE_II
PS51447--FDX_ACB
Pfam

PF03147--FDX-ACB
PF01409--tRNA-synt_2d
Gene Ontology

GO:0005737--C:cytoplasm
GO:0005759--C:mitochondrial matrix
GO:0005739--C:mitochondrion
GO:0005524--F:ATP binding
GO:0000287--F:magnesium ion binding
GO:0004826--F:phenylalanine-tRNA ligase activity
GO:0000049--F:tRNA binding
GO:0070156--P:mitochondrial phenylalanyl-tRNA aminoacylation
GO:0006432--P:phenylalanyl-tRNA aminoacylation
GO:0008033--P:tRNA processing