dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0004748
Uniprot Accession P08417; FUMH_YEAST; D6W3A8; Q08978;
Genbank Protein ID NP_015061.1;
Genbank Nucleotide ID NM_001184076.1;
Protein Name Fumarate hydratase, mitochondrial
Protein Synonyms/Alias
Gene Name FUM1
Gene Synonyms/Alias YPL262W;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)
Phosphorylation Sites
 dbPAF PTMs: 2
PositionPeptidesSourceReferences ( PMIDs )
122FPLVVFQTGSGTQSNcurated22369663
428PRIHELLTKSLMLVTdbPTM 3.0;PhosphoGRID 2.0;UniProt17761666; 16381945; 23193290
Sequence
(Fasta)		MLRFTNCSCK TFVKSSYKLN IRRMNSSFRT ETDAFGEIHV PADKYWGAQT QRSFQNFKIG 60
GARERMPLPL VHAFGVLKKS AAIVNESLGG LDPKISKAIQ QAADEVASGK LDDHFPLVVF 120
QTGSGTQSNM NANEVISNRA IEILGGKIGS KQVHPNNHCN QSQSSNDTFP TVMHIAASLQ 180
IQNELIPELT NLKNALEAKS KEFDHIVKIG RTHLQDATPL TLGQEFSGYV QQVENGIQRV 240
AHSLKTLSFL AQGGTAVGTG LNTKPGFDVK IAEQISKETG LKFQTAPNKF EALAAHDAIV 300
ECSGALNTLA CSLFKIAQDI RYLGSGPRCG YHELMLPENE PGSSIMPGKV NPTQNEALTQ 360
VCVQVMGNNA AITFAGSQGQ FELNVFKPVM IANLLNSIRL ITDAAYSFRV HCVEGIKANE 420
PRIHELLTKS LMLVTALNPK IGYDAASKVA KNAHKKGITL KESALELGVL TEKEFDEWVV 480
PEHMLGPK 489
Keyword

KW-0002--3D-structure
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0903--Direct protein sequencing
KW-0456--Lyase
KW-0496--Mitochondrion
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0809--Transit peptide
KW-0816--Tricarboxylic acid cycle
Interpro

IPR005677--Fum_hydII
IPR024083--Fumarase/histidase_N
IPR018951--Fumarase_C_C
IPR020557--Fumarate_lyase_CS
IPR000362--Fumarate_lyase_fam
IPR022761--Fumarate_lyase_N
IPR008948--L-Aspartase-like
PROSITE

PS00163--FUMARATE_LYASES
Pfam

PF10415--FumaraseC_C
PF00206--Lyase_1
Gene Ontology

GO:0005829--C:cytosol
GO:0005759--C:mitochondrial matrix
GO:0005739--C:mitochondrion
GO:0045239--C:tricarboxylic acid cycle enzyme complex
GO:0004333--F:fumarate hydratase activity
GO:0006106--P:fumarate metabolic process
GO:0006108--P:malate metabolic process
GO:0051262--P:protein tetramerization
GO:0006099--P:tricarboxylic acid cycle