| Tag |
Content |
| dbPAF ID |
dbPAF-0004719 |
| Uniprot Accession |
P08181; CSK2A_DROME; Q0E8B4; Q9W5T2;
|
| Genbank Protein ID |
NP_001036624.1; NP_001287151.1; NP_001287152.1; NP_001287153.1; NP_524918.1; NP_730774.1; NP_730775.1;
|
| Genbank Nucleotide ID |
NM_001043159.3; NM_001300222.1; NM_001300223.1; NM_001300224.1; NM_080179.5; NM_168985.2; NM_168986.2;
|
| Protein Name |
Casein kinase II subunit alpha |
| Protein Synonyms/Alias |
|
| Gene Name |
CkIIalpha |
| Gene Synonyms/Alias |
Cask-II-a;CG17520; |
| Organism |
Drosophila melanogaster(Fruit fly) |
| NCBI Taxa ID |
7227 |
Functional Description
(View all) |
Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. The alpha chain contains the catalytic site. May participate in Wnt signaling.Functional Description
Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. The alpha chain contains the catalytic site. May participate in Wnt signaling. |
Phosphorylation Sites
|
dbPAF PTMs: 1 | Position | Peptides | Source | References ( PMIDs ) |
|---|
| 285 | RWERFVHSDNQHLVS | PHOSIDA;curated | 21081558; 22817900 |
|
Sequence
(Fasta) | MTLPSAARVY TDVNAHKPDE YWDYENYVVD WGNQDDYQLV RKLGRGKYSE VFEAINITTT 60
EKCVVKILKP VKKKKIKREI KILENLRGGT NIITLLAVVK DPVSRTPALI FEHVNNTDFK 120
QLYQTLTDYE IRYYLFELLK ALDYCHSMGI MHRDVKPHNV MIDHENRKLR LIDWGLAEFY 180
HPGQEYNVRV ASRYFKGPEL LVDYQMYDYS LDMWSLGCML ASMIFRKEPF FHGHDNYDQL 240
VRIAKVLGTE ELYAYLDKYN IDLDPRFHDI LQRHSRKRWE RFVHSDNQHL VSPEALDFLD 300
KLLRYDHVDR LTAREAMAHP YFLPIVNGQM NPNNQQ
337Fasta Sequence
>P08181|CkIIalpha|Drosophila melanogaster(Fruit fly)
MTLPSAARVYTDVNAHKPDEYWDYENYVVDWGNQDDYQLVRKLGRGKYSEVFEAINITTTEKCVVKILKPVKKKKIKREIKILENLRGGTNIITLLAVVKDPVSRTPALIFEHVNNTDFKQLYQTLTDYEIRYYLFELLKALDYCHSMGIMHRDVKPHNVMIDHENRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEELYAYLDKYNIDLDPRFHDILQRHSRKRWERFVHSDNQHLVSPEALDFLDKLLRYDHVDRLTAREAMAHPYFLPIVNGQMNPNNQQ
|
| Keyword |
KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0903--Direct protein sequencing
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0723--Serine/threonine-protein kinase
KW-0808--Transferase
KW-0879--Wnt signaling pathway
|
| Interpro |
IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR002290--Ser/Thr_dual-sp_kinase
IPR008271--Ser/Thr_kinase_AS
|
| PROSITE |
PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST
|
| Pfam |
PF00069--Pkinase
|
| Gene Ontology |
GO:0005737--C:cytoplasm
GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0005956--C:protein kinase CK2 complex
GO:0005524--F:ATP binding
GO:0004672--F:protein kinase activity
GO:0004674--F:protein serine/threonine kinase activity
GO:0007411--P:axon guidance
GO:0009267--P:cellular response to starvation
GO:0022416--P:chaeta development
GO:0007623--P:circadian rhythm
GO:0048749--P:compound eye development
GO:0060810--P:intracellular mRNA localization involved in pattern specification process
GO:0046331--P:lateral inhibition
GO:0045475--P:locomotor rhythm
GO:0007067--P:mitotic nuclear division
GO:0031397--P:negative regulation of protein ubiquitination
GO:0007310--P:oocyte dorsal/ventral axis specification
GO:0007228--P:positive regulation of hh target transcription factor activity
GO:0045880--P:positive regulation of smoothened signaling pathway
GO:0030177--P:positive regulation of Wnt signaling pathway
GO:0006468--P:protein phosphorylation
GO:0031647--P:regulation of protein stability
GO:0016055--P:Wnt signaling pathway
|
