dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0004640
Uniprot Accession P07806; SYV_YEAST; D6VUM6;
Genbank Protein ID NP_011608.1;
Genbank Nucleotide ID NM_001181223.1;
Protein Name Valine--tRNA ligase, mitochondrial
Protein Synonyms/Alias Valyl-tRNA synthetase;ValRS;
Gene Name VAS1
Gene Synonyms/Alias YGR094W;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)
Phosphorylation Sites
 dbPAF PTMs: 9
PositionPeptidesSourceReferences ( PMIDs )
38FSLKKSLTHNQVRFFcurated22817900; 20377248; 19547744
73NPLKEDGSPKTPKEIdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;UniProt;curated18407956; 16381945; 23193290; 19366988; 24961812
109AAATTGASQKKPKKKcurated25315811
294SREAFTLSPELTKSVdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;UniProt;curated18407956; 16381945; 23193290; 19366988; 22369663; 22817900;
332VKLNTAISNLEVENKdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;UniProt;curated18407956; 16381945; 23193290; 19366988
362KVEFGVLTSFAYPVIcurated19823750
496QLKEKNLYVGQEDNEcurated22817900; 19547744
707QGRKMSKSLGNVIDPdbPTM 3.0;PhosphoGRID 2.0;PhosphoPep 2.0;SysPTM 2.0;UniProt;curated18407956; 16381945; 23193290; 19060867; 19366988; 26040289;
1003IKAIDEVTVVRDASEdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;UniProt;curated18407956; 16381945; 23193290; 19366988
Sequence
(Fasta)		MNKWLNTLSK TFTFRLLNCH YRRSLPLCQN FSLKKSLTHN QVRFFKMSDL DNLPPVDPKT 60
GEVIINPLKE DGSPKTPKEI EKEKKKAEKL LKFAAKQAKK NAAATTGASQ KKPKKKKEVE 120
PIPEFIDKTV PGEKKILVSL DDPALKAYNP ANVESSWYDW WIKTGVFEPE FTADGKVKPE 180
GVFCIPAPPP NVTGALHIGH ALTIAIQDSL IRYNRMKGKT VLFLPGFDHA GIATQSVVEK 240
QIWAKDRKTR HDYGREAFVG KVWEWKEEYH SRIKNQIQKL GASYDWSREA FTLSPELTKS 300
VEEAFVRLHD EGVIYRASRL VNWSVKLNTA ISNLEVENKD VKSRTLLSVP GYDEKVEFGV 360
LTSFAYPVIG SDEKLIIATT RPETIFGDTA VAVHPDDDRY KHLHGKFIQH PFLPRKIPII 420
TDKEAVDMEF GTGAVKITPA HDQNDYNTGK RHNLEFINIL TDDGLLNEEC GPEWQGMKRF 480
DARKKVIEQL KEKNLYVGQE DNEMTIPTCS RSGDIIEPLL KPQWWVSQSE MAKDAIKVVR 540
DGQITITPKS SEAEYFHWLG NIQDWCISRQ LWWGHRCPVY FINIEGEEHD RIDGDYWVAG 600
RSMEEAEKKA AAKYPNSKFT LEQDEDVLDT WFSSGLWPFS TLGWPEKTKD METFYPFSML 660
ETGWDILFFW VTRMILLGLK LTGSVPFKEV FCHSLVRDAQ GRKMSKSLGN VIDPLDVITG 720
IKLDDLHAKL LQGNLDPREV EKAKIGQKES YPNGIPQCGT DAMRFALCAY TTGGRDINLD 780
ILRVEGYRKF CNKIYQATKF ALMRLGDDYQ PPATEGLSGN ESLVEKWILH KLTETSKIVN 840
EALDKRDFLT STSSIYEFWY LICDVYIENS KYLIQEGSAI EKKSAKDTLY ILLDNALKLI 900
HPFMPFISEE MWQRLPKRST EKAASIVKAS YPVYVSEYDD VKSANAYDLV LNITKEARSL 960
LSEYNILKNG KVFVESNHEE YFKTAEDQKD SIVSLIKAID EVTVVRDASE IPEGCVLQSV 1020
NPEVNVHLLV KGHVDIDAEI AKVQKKLEKA KKSKNGIEQT INSKDYETKA NTQAKEANKS 1080
KLDNTVAEIE GLEATIENLK RLKL 1105
Keyword

KW-0024--Alternative initiation
KW-0030--Aminoacyl-tRNA synthetase
KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0436--Ligase
KW-0496--Mitochondrion
KW-0547--Nucleotide-binding
KW-0597--Phosphoprotein
KW-0648--Protein biosynthesis
KW-1185--Reference proteome
KW-0809--Transit peptide
Interpro

IPR001412--aa-tRNA-synth_I_CS
IPR002300--aa-tRNA-synth_Ia
IPR013155--M/V/L/I-tRNA-synth_anticd-bd
IPR014729--Rossmann-like_a/b/a_fold
IPR010978--tRNA-bd_arm
IPR009080--tRNAsynth_1a_anticodon-bd
IPR009008--Val/Leu/Ile-tRNA-synth_edit
IPR002303--Valyl-tRNA_ligase
PROSITE

PS00178--AA_TRNA_LIGASE_I
Pfam

PF08264--Anticodon_1
PF00133--tRNA-synt_1
Gene Ontology

GO:0005737--C:cytoplasm
GO:0005739--C:mitochondrion
GO:0002161--F:aminoacyl-tRNA editing activity
GO:0005524--F:ATP binding
GO:0004832--F:valine-tRNA ligase activity
GO:0006438--P:valyl-tRNA aminoacylation