dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0004617
Uniprot Accession P07664; SRYD_DROME; Q9VAB3;
Genbank Protein ID NP_524581.1;
Genbank Nucleotide ID NM_079842.3;
Protein Name Serendipity locus protein delta
Protein Synonyms/Alias
Gene Name Sry-delta
Gene Synonyms/Alias Sry-d;CG17958;
Organism Drosophila melanogaster(Fruit fly)
NCBI Taxa ID 7227
Functional Description
(View all)
Transcriptional activator that controls bicoid gene expression during oogenesis. Found in transcriptionally active cells. Binds to specific sites on polytene chromosomes of third instar larvae. Binds to the consensus DNA sequence 5'-YTAGAGATGGRAA-3'.
Phosphorylation Sites
dbPAF PTMs: 3
PositionPeptidesSourceReferences ( PMIDs )
140LVKDQEESDTEIKREPHOSIDA;curated21081558; 22817900
180SEALYGKSSDGEDRPPHOSIDA;curated21081558; 22817900
181EALYGKSSDGEDRPTPHOSIDA;curated21081558; 22817900
Sequence
(Fasta)
MDTCFFCGAV DLSDTGSSSS MRYETLSAKV PSSQKTVSLV LTHLANCIQT QLDLKPGARL 60
CPRCFQELSD YDTIMVNLMT TQKRLTTQLK GALKSEFEVP ESGEDILVEE VEIPQSDVET 120
DADAEADALF VELVKDQEES DTEIKREFVD EEEEEDDDDD DEFICEDVDV GDSEALYGKS 180
SDGEDRPTKK RVKQECTTCG KVYNSWYQLQ KHISEEHSKQ PNHICPICGV IRRDEEYLEL 240
HMNLHEGKTE KQCRYCPKSF SRPVNTLRHM RMHWDKKKYQ CEKCGLRFSQ DNLLYNHRLR 300
HEAEENPIIC SICNVSFKSR KTFNHHTLIH KENRPRHYCS VCPKSFTERY TLKMHMKTHE 360
GDVVYGVREE APADEQQVVE ELHVDVDESE AAVTVIMSDN DENSGFCLIC NTNFENKKEL 420
EHHLQFDHDV VLK 434
Keyword

KW-0010--Activator
KW-0181--Complete proteome
KW-0217--Developmental protein
KW-0238--DNA-binding
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR007087--Znf_C2H2
IPR015880--Znf_C2H2-like
IPR013087--Znf_C2H2/integrase_DNA-bd

PROSITE

PS00028--ZINC_FINGER_C2H2_1
PS50157--ZINC_FINGER_C2H2_2

Pfam

PF00096--zf-C2H2

Gene Ontology

GO:0005634--C:nucleus
GO:0005705--C:polytene chromosome interband
GO:0003677--F:DNA binding
GO:0046872--F:metal ion binding
GO:0001077--F:transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0008595--P:anterior/posterior axis specification, embryo
GO:0045450--P:bicoid mRNA localization
GO:0032504--P:multicellular organism reproduction
GO:0048477--P:oogenesis
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0006366--P:transcription from RNA polymerase II promoter