dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0004588
Uniprot Accession P07347; ARD1_YEAST; D3DKV8;
Genbank Protein ID NP_011877.1;
Genbank Nucleotide ID NM_001179143.1;
Protein Name N-terminal acetyltransferase A complex catalytic subunit ARD1
Protein Synonyms/Alias
Gene Name ARD1
Gene Synonyms/Alias YHR013C;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)
Catalytic component of the NatA N-terminal acetyltransferase, which catalyzes acetylation of proteins beginning with Met-Ser, Met-Gly and Met-Ala. N-acetylation plays a role in normal eukaryotic translation and processing, protect against proteolytic degradation and protein turnover.
Phosphorylation Sites
dbPAF PTMs: 1
PositionPeptidesSourceReferences ( PMIDs )
222KLEDDLESDLLEDIIcurated22369663; 24961812
Sequence
(Fasta)
MPINIRRATI NDIICMQNAN LHNLPENYMM KYYMYHILSW PEASFVATTT TLDCEDSDEQ 60
DENDKLELTL DGTNDGRTIK LDPTYLAPGE KLVGYVLVKM NDDPDQQNEP PNGHITSLSV 120
MRTYRRMGIA ENLMRQALFA LREVHQAEYV SLHVRQSNRA ALHLYRDTLA FEVLSIEKSY 180
YQDGEDAYAM KKVLKLEELQ ISNFTHRRLK ENEEKLEDDL ESDLLEDIIK QGVNDIIV 239
Keyword

KW-0002--3D-structure
KW-0012--Acyltransferase
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-1185--Reference proteome
KW-0808--Transferase

Interpro

IPR016181--Acyl_CoA_acyltransferase
IPR000182--GNAT_dom

PROSITE

PS51186--GNAT

Pfam

PF00583--Acetyltransf_1

Gene Ontology

GO:0031415--C:NatA complex
GO:0042802--F:identical protein binding
GO:1990190--F:peptide-glutamate-N-acetyltransferase activity
GO:1990189--F:peptide-serine-N-acetyltransferase activity
GO:0016573--P:histone acetylation
GO:0018002--P:N-terminal peptidyl-glutamic acid acetylation
GO:0017198--P:N-terminal peptidyl-serine acetylation
GO:0006474--P:N-terminal protein amino acid acetylation
GO:0061606--P:N-terminal protein amino acid propionylation