dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0004587
Uniprot Accession P07342; ILVB_YEAST; D6VZT1;
Genbank Protein ID NP_013826.1;
Genbank Nucleotide ID NM_001182608.1;
Protein Name Acetolactate synthase catalytic subunit, mitochondrial
Protein Synonyms/Alias Acetohydroxy-acid synthase catalytic subunit;AHAS;ALS;
Gene Name ILV2
Gene Synonyms/Alias SMR1;YMR108W;YM9718.07;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)
Phosphorylation Sites
 dbPAF PTMs: 1
PositionPeptidesSourceReferences ( PMIDs )
270PTKTTLPSNALNQLTdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 19366988
Sequence
(Fasta)		MIRQSTLKNF AIKRCFQHIA YRNTPAMRSV ALAQRFYSSS SRYYSASPLP ASKRPEPAPS 60
FNVDPLEQPA EPSKLAKKLR AEPDMDTSFV GLTGGQIFNE MMSRQNVDTV FGYPGGAILP 120
VYDAIHNSDK FNFVLPKHEQ GAGHMAEGYA RASGKPGVVL VTSGPGATNV VTPMADAFAD 180
GIPMVVFTGQ VPTSAIGTDA FQEADVVGIS RSCTKWNVMV KSVEELPLRI NEAFEIATSG 240
RPGPVLVDLP KDVTAAILRN PIPTKTTLPS NALNQLTSRA QDEFVMQSIN KAADLINLAK 300
KPVLYVGAGI LNHADGPRLL KELSDRAQIP VTTTLQGLGS FDQEDPKSLD MLGMHGCATA 360
NLAVQNADLI IAVGARFDDR VTGNISKFAP EARRAAAEGR GGIIHFEVSP KNINKVVQTQ 420
IAVEGDATTN LGKMMSKIFP VKERSEWFAQ INKWKKEYPY AYMEETPGSK IKPQTVIKKL 480
SKVANDTGRH VIVTTGVGQH QMWAAQHWTW RNPHTFITSG GLGTMGYGLP AAIGAQVAKP 540
ESLVIDIDGD ASFNMTLTEL SSAVQAGTPV KILILNNEEQ GMVTQWQSLF YEHRYSHTHQ 600
LNPDFIKLAE AMGLKGLRVK KQEELDAKLK EFVSTKGPVL LEVEVDKKVP VLPMVAGGSG 660
LDEFINFDPE VERQQTELRH KRTGGKH 688
Keyword

KW-0002--3D-structure
KW-0028--Amino-acid biosynthesis
KW-0100--Branched-chain amino acid biosynthesis
KW-0181--Complete proteome
KW-0460--Magnesium
KW-0479--Metal-binding
KW-0496--Mitochondrion
KW-1185--Reference proteome
KW-0786--Thiamine pyrophosphate
KW-0808--Transferase
KW-0809--Transit peptide
Interpro

IPR012846--Acetolactate_synth_lsu
IPR029035--DHS-like_NAD/FAD-binding_dom
IPR029061--THDP-binding
IPR012000--Thiamin_PyroP_enz_cen_dom
IPR012001--Thiamin_PyroP_enz_TPP-bd_dom
IPR000399--TPP-bd_CS
IPR011766--TPP_enzyme-bd_C
PROSITE

PS00187--TPP_ENZYMES
Pfam

PF02775--TPP_enzyme_C
PF00205--TPP_enzyme_M
PF02776--TPP_enzyme_N
Gene Ontology

GO:0005948--C:acetolactate synthase complex
GO:0005739--C:mitochondrion
GO:0003984--F:acetolactate synthase activity
GO:0050660--F:flavin adenine dinucleotide binding
GO:0000287--F:magnesium ion binding
GO:0030976--F:thiamine pyrophosphate binding
GO:0009082--P:branched-chain amino acid biosynthetic process
GO:0009097--P:isoleucine biosynthetic process
GO:0009099--P:valine biosynthetic process