dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0004567
Uniprot Accession P07284; SYSC_YEAST; D6VS09;
Genbank Protein ID NP_010306.1;
Genbank Nucleotide ID NM_001180331.1;
Protein Name Serine--tRNA ligase, cytoplasmic
Protein Synonyms/Alias Seryl-tRNA synthetase;SerRS;Seryl-tRNA(Ser/Sec) synthetase;
Gene Name SES1
Gene Synonyms/Alias SERS;YDR023W;YD9813.01;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)		 Catalyzes the attachment of serine to tRNA(Ser). Is also probably able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
Phosphorylation Sites
 dbPAF PTMs: 6
PositionPeptidesSourceReferences ( PMIDs )
28SQKARNASVEIVDEIcurated24961812
119VHPSVVVSNDEENNEdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 19366988; 22817900
225MSKTAQLSEFDEELYcurated22369663; 22817900; 24961812
453NELPKNSTSSKDKKKcurated22817900
454ELPKNSTSSKDKKKKcurated22817900
455LPKNSTSSKDKKKKNcurated22817900
Sequence
(Fasta)		MLDINQFIED KGGNPELIRQ SQKARNASVE IVDEIISDYK DWVKTRFELD ELNKKFNKLQ 60
KDIGLKFKNK EDASGLLAEK EKLTQQKKEL TEKEQQEDKD LKKKVFQVGN IVHPSVVVSN 120
DEENNELVRT WKPEDLEAVG PIASVTGKPA SLSHHEILLR LDGYDPDRGV KICGHRGYFF 180
RNYGVFLNQA LINYGLQFLA AKGYIPLQAP VMMNKELMSK TAQLSEFDEE LYKVIDGEDE 240
KYLIATSEQP ISAYHSGEWF EKPQEQLPIH YVGYSSCFRR EAGSHGKDAW GVFRVHAFEK 300
IEQFVITEPE KSWEEFEKMI SYSEEFYKSL KLPYRIVGIV SGELNNAAAK KYDLEAWFPY 360
QKEYKELVSC SNCTDYQSRN LEIRCGIKKM GDREKKYVHC LNSTLAATQR ALCCILENYQ 420
TEDGLVVPEV LRKYIPGEPE FLPFVNELPK NSTSSKDKKK KN 463
Keyword

KW-0030--Aminoacyl-tRNA synthetase
KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0436--Ligase
KW-0547--Nucleotide-binding
KW-0648--Protein biosynthesis
KW-1185--Reference proteome
Interpro

IPR002314--aa-tRNA-synt_IIb
IPR006195--aa-tRNA-synth_II
IPR002317--Ser-tRNA-ligase_type_1
IPR015866--Ser-tRNA-synth_1_N
IPR010978--tRNA-bd_arm
PROSITE

PS50862--AA_TRNA_LIGASE_II
Pfam

PF02403--Seryl_tRNA_N
PF00587--tRNA-synt_2b
Gene Ontology

GO:0005737--C:cytoplasm
GO:0005524--F:ATP binding
GO:0004828--F:serine-tRNA ligase activity
GO:0097056--P:selenocysteinyl-tRNA(Sec) biosynthetic process
GO:0006434--P:seryl-tRNA aminoacylation