dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0004566
Uniprot Accession P07283; PMM_YEAST; D6VTI5; Q70D76; Q70D77;
Genbank Protein ID NP_116609.1;
Genbank Nucleotide ID NM_001179922.1;
Protein Name Phosphomannomutase
Protein Synonyms/Alias
Gene Name SEC53
Gene Synonyms/Alias ALG4;YFL045C;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)
Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.
Phosphorylation Sites
dbPAF PTMs: 5
PositionPeptidesSourceReferences ( PMIDs )
2------MSIAEFAYKdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 19366988; 22369663; 19547744
54CIGFVGGSDLSKQLEdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 19366988
233EIFVDERTIGHSVQScurated25315811
237DERTIGHSVQSPDDTPhosphoPep 2.019060867
240TIGHSVQSPDDTVKIdbPTM 3.0;PhosphoGRID 2.0;PhosphoPep 2.0;SysPTM 2.0;UniProt;curated17330950; 17563356; 18407956; 16381945; 23193290; 20702584;
Sequence
(Fasta)
MSIAEFAYKE KPETLVLFDV DGTLTPARLT VSEEVRKTLA KLRNKCCIGF VGGSDLSKQL 60
EQLGPNVLDE FDYSFSENGL TAYRLGKELA SQSFINWLGE EKYNKLAVFI LRYLSEIDLP 120
KRRGTFLEFR NGMINVSPIG RNASTEERNE FERYDKEHQI RAKFVEALKK EFPDYGLTFS 180
IGGQISFDVF PAGWDKTYCL QHVEKDGFKE IHFFGDKTMV GGNDYEIFVD ERTIGHSVQS 240
PDDTVKILTE LFNL 255
Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0413--Isomerase
KW-0597--Phosphoprotein
KW-1185--Reference proteome

Interpro

IPR023214--HAD-like_dom
IPR006379--HAD-SF_hydro_IIB
IPR005002--PMM

PROSITE
Pfam

PF03332--PMM

Gene Ontology

GO:0005829--C:cytosol
GO:0004615--F:phosphomannomutase activity
GO:0009298--P:GDP-mannose biosynthetic process
GO:0045047--P:protein targeting to ER