dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0004558
Uniprot Accession P07272; PPR1_YEAST; D6VY16;
Genbank Protein ID NP_013114.1;
Genbank Nucleotide ID NM_001181901.1;
Protein Name Pyrimidine pathway regulatory protein 1
Protein Synonyms/Alias
Gene Name PPR1
Gene Synonyms/Alias YLR014C;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)
Positive regulator of URA1 and URA3 expression.
Phosphorylation Sites
dbPAF PTMs: 9
PositionPeptidesSourceReferences ( PMIDs )
22DLSKRGDSPNIGISKPhosphoGRID 2.0;curated19779198; 22817900; 25315811; 20377248
160ITSKSMASPQTINVQdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 19366988; 25315811
189ALLPETGSPMTSDARcurated25315811
217LGTMRESSFNSFLGDdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 19366988
244ATNFRQDSGDDVLDEcurated22817900
734CESAKTCYTSYKILScurated26040289
741YTSYKILSSVVIKLKcurated26040289
880WDEFFVRSGNGNEGEcurated22817900
893GESSYDISKGKNSEScurated22817900
Sequence
(Fasta)
MKQKKFNSKK SNRTDLSKRG DSPNIGISKS RTACKRCRLK KIKCDQEFPS CKRCAKLEVP 60
CVSLDPATGK DVPRSYVFFL EDRLAVMMRV LKEYGVDPTK IRGNIPATSD DEPFDLKKYS 120
SVSSLGEEGI LPHNGLLADY LVQKGNSMAS SAITSKSMAS PQTINVQRKE FLVNSKKQDG 180
SALLPETGSP MTSDARAEEL RRCNKEISAL GTMRESSFNS FLGDSSGISF AKLVFTATNF 240
RQDSGDDVLD EDIKQREQKY NGYAEAENNP HFDPLELPPR HAAEVMISRF FVDTNSQLPL 300
LHRELFLKKY FEPIYGPWNP NIALASDQTG INSAFEIPIT SAFSAHTEPK RENVTEKIDV 360
CSSVDVPWYD TWETSQKVNM RPIVELPTKF HIPYFFLNII FAIGHATQVL KSDITTVATY 420
KRRATKYIAS LFSSSDRLEA LAGTLLMVIY SIMRPNVPGV WYTMGSVLRL TVDLGLHSEK 480
INKNYDAFTR EIRRRLFWCV YSLDRQICSY FGRPFGIPEE SITTRYPSLL DDSFITLTNR 540
EIDDYSDLPS PNPSSKVIAL AMYKIRRIQA SIVRILYAPG AELPRRFMDL ESWRIETYNE 600
LERWFQVDVP KNFEMMNCKF NSIWFDLNYH YSKSILYGLS PKFPTLNDTA FKIVLDSTKG 660
TIDVFYNLCV NKKIGYTWVA VHNMFMTGMT YLYVNFYSKN NINDCQEKVS EYTEKVLIVL 720
KNLIGFCESA KTCYTSYKIL SSVVIKLKFM QINDAKGIFS DSNPLTSQAN RMSSYDKKTN 780
VLGFDDGTFD NKVFNRTNFE EKAPFDIPLD EFFTELEKHS NVSQFNTLDV SEGNQVINES 840
ASTNTSSALN CQSYTNNQDI MDILFQVTSG SVWDEFFVRS GNGNEGESSY DISKGKNSES 900
GGIF 905
Keyword

KW-0002--3D-structure
KW-0010--Activator
KW-0181--Complete proteome
KW-0238--DNA-binding
KW-0479--Metal-binding
KW-0539--Nucleus
KW-0665--Pyrimidine biosynthesis
KW-1185--Reference proteome
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0862--Zinc

Interpro

IPR007219--Transcription_factor_dom_fun
IPR001138--Zn2-C6_fun-type_DNA-bd

PROSITE

PS00463--ZN2_CY6_FUNGAL_1
PS50048--ZN2_CY6_FUNGAL_2

Pfam

PF04082--Fungal_trans
PF00172--Zn_clus

Gene Ontology

GO:0005634--C:nucleus
GO:0000981--F:RNA polymerase II transcription factor activity, sequence-specific DNA binding
GO:0043565--F:sequence-specific DNA binding
GO:0008270--F:zinc ion binding
GO:1900399--P:positive regulation of pyrimidine nucleotide biosynthetic process
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0006221--P:pyrimidine nucleotide biosynthetic process
GO:0006351--P:transcription, DNA-templated