dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0004548
Uniprot Accession P07257; QCR2_YEAST; D6W4J1;
Genbank Protein ID NP_015517.1;
Genbank Nucleotide ID NM_001184288.1;
Protein Name Cytochrome b-c1 complex subunit 2, mitochondrial
Protein Synonyms/Alias Complex III subunit 2;Core protein II;Ubiquinol-cytochrome-c reductase complex core protein 2;
Gene Name QCR2
Gene Synonyms/Alias COR2;UCR2;YPR191W;P9677.6;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain that generates an electrochemical potential coupled to ATP synthesis. The complex couples electron transfer from ubiquinol to cytochrome c. QCR2 is required for the assembly of the complex.
Phosphorylation Sites
dbPAF PTMs: 5
PositionPeptidesSourceReferences ( PMIDs )
141AEQCPVKSAEDQLYAdbPTM 3.0;PhosphoGRID 2.0;UniProt17761666; 16381945; 23193290
168YDGVERVSLQDIKDFPhosphoGRID 2.0;UniProt;curated19779198; 22369663; 22817900; 24961812
280SAKLDKFTDGGLFTLPhosphoGRID 2.021126336
315LKKGKDLSPAINYTKcurated25315811
321LSPAINYTKLKNAVQcurated25315811
Sequence
(Fasta)
MLSAARLQFA QGSVRRLTVS ARDAPTKIST LAVKVHGGSR YATKDGVAHL LNRFNFQNTN 60
TRSALKLVRE SELLGGTFKS TLDREYITLK ATFLKDDLPY YVNALADVLY KTAFKPHELT 120
ESVLPAARYD YAVAEQCPVK SAEDQLYAIT FRKGLGNPLL YDGVERVSLQ DIKDFADKVY 180
TKENLEVSGE NVVEADLKRF VDESLLSTLP AGKSLVSKSE PKFFLGEENR VRFIGDSVAA 240
IGIPVNKASL AQYEVLANYL TSALSELSGL ISSAKLDKFT DGGLFTLFVR DQDSAVVSSN 300
IKKIVADLKK GKDLSPAINY TKLKNAVQNE SVSSPIELNF DAVKDFKLGK FNYVAVGDVS 360
NLPYLDEL 369
Keyword

KW-0002--3D-structure
KW-0181--Complete proteome
KW-0249--Electron transport
KW-0472--Membrane
KW-0496--Mitochondrion
KW-0999--Mitochondrion inner membrane
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0679--Respiratory chain
KW-0809--Transit peptide
KW-0813--Transport

Interpro

IPR011249--Metalloenz_LuxS/M16
IPR011237--Pept_M16_dom
IPR011765--Pept_M16_N
IPR001431--Pept_M16_Zn_BS

PROSITE

PS00143--INSULINASE

Pfam

PF00675--Peptidase_M16

Gene Ontology

GO:0030061--C:mitochondrial crista
GO:0005750--C:mitochondrial respiratory chain complex III
GO:0005739--C:mitochondrion
GO:0046872--F:metal ion binding
GO:0004222--F:metalloendopeptidase activity
GO:0009060--P:aerobic respiration
GO:1902600--P:hydrogen ion transmembrane transport
GO:0006122--P:mitochondrial electron transport, ubiquinol to cytochrome c