dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0004540
Uniprot Accession P07248; ADR1_YEAST; D6VSJ9; Q04919;
Genbank Protein ID NP_010502.3;
Genbank Nucleotide ID NM_001180524.3;
Protein Name Regulatory protein ADR1
Protein Synonyms/Alias
Gene Name ADR1
Gene Synonyms/Alias YDR216W;YD8142.16;YD8142B.08;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)		 Required for transcriptional activation of glucose-repressible alcohol dehydrogenase (ADH2).
Phosphorylation Sites
 dbPAF PTMs: 49 (View all)
PositionPeptidesSourceReferences ( PMIDs )
54SSASRENSNTFSVIQPhosphoGRID 2.0;UniProt;curated19779198; 20489023; 22817900
98RLNGRTPSGKLRSFVPhosphoGRID 2.018791642
127KRHYRSHTNEKPYPCcurated22817900; 19547744
180ITKARKNSASSVKFQPhosphoGRID 2.0;PhosphoPep 2.0;curated19823750; 19779198; 19795423; 19060867; 26040289; 22817900;
182KARKNSASSVKFQTPPhosphoGRID 2.0;PhosphoPep 2.0;curated21177495; 19779198; 19060867; 26040289; 22817900
183ARKNSASSVKFQTPTPhosphoGRID 2.0;PhosphoPep 2.0;curated21177495; 19779198; 19060867; 22817900
188ASSVKFQTPTYGTPDPhosphoGRID 2.0;UniProt;curated19779198; 26040289; 22369663; 22817900
191VKFQTPTYGTPDNGNPhosphoGRID 2.0;curated19779198; 25315811
193FQTPTYGTPDNGNFLdbPTM 3.0;PhosphoGRID 2.0;PhosphoPep 2.0;SysPTM 2.0;UniProt;curated18407956; 16381945; 23193290; 19779198; 20489023; 19060867;
212ANTRRKASPEANVKRdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 20489023; 19366988; 24961812;
221EANVKRKYLKKLTRRcurated22817900; 19547744
226RKYLKKLTRRASFSAcurated22817900; 19547744
230KKLTRRASFSAQSASdbPTM 3.0;Phospho.ELM 9.0;PhosphoGRID 2.0;PhosphoPep 2.0;SysPTM 2.0;curated1549108; 18407956; 16381945; 23193290; 8910470; 2644045; 173
232LTRRASFSAQSASSYdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;curated17287358; 16381945; 23193290; 19366988; 22817900; 23607784
235RASFSAQSASSYALPPhosphoGRID 2.019779198
239SAQSASSYALPDQSSPhosphoGRID 2.0;curated19779198; 22817900
258PKDRVKFSTPELVPLPhosphoGRID 2.0;PhosphoPep 2.0;UniProt;curated21126336; 19779198; 19060867; 22817900; 19823750; 25521595
259KDRVKFSTPELVPLDdbPTM 3.0;PhosphoGRID 2.0;PHOSIDA;PhosphoPep 2.0;SysPTM 2.0;UniProt;curated15665377; 18407956; 16381945; 23193290; 19823750; 19779198;
299FNIALNRSDSSGSTMPhosphoGRID 2.0;UniProt;curated21177495; 19779198; 20489023; 26040289; 22817900
301IALNRSDSSGSTMNLdbPTM 3.0;PhosphoGRID 2.0;PhosphoPep 2.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 20489023; 19060867; 19366988;
Sequence
(Fasta)		MANVEKPNDC SGFPVVDLNS CFSNGFNNEK QEIEMETDDS PILLMSSSAS RENSNTFSVI 60
QRTPDGKIIT TNNNMNSKIN KQLDKLPENL RLNGRTPSGK LRSFVCEVCT RAFARQEHLK 120
RHYRSHTNEK PYPCGLCNRC FTRRDLLIRH AQKIHSGNLG ETISHTKKVS RTITKARKNS 180
ASSVKFQTPT YGTPDNGNFL NRTTANTRRK ASPEANVKRK YLKKLTRRAS FSAQSASSYA 240
LPDQSSLEQH PKDRVKFSTP ELVPLDLKNP ELDSSFDLNM NLDLNLNLDS NFNIALNRSD 300
SSGSTMNLDY KLPESANNYT YSSGSPTRAY VGANTNSKNA SFNDADLLSS SYWIKAYNDH 360
LFSVSESDET SPMNSELNDT KLIVPDFKST IHHLKDSRSS SWTVAIDNNS NNNKVSDNQP 420
DFVDFQELLD NDTLGNDLLE TTAVLKEFEL LHDDSVSATA TSNEIDLSHL NLSNSPISPH 480
KLIYKNKEGT NDDMLISFGL DHPSNREDDL DKLCNMTRDV QAIFSQYLKG EESKRSLEDF 540
LSTSNRKEKP DSGNYTFYGL DCLTLSKISR ALPASTVNNN QPSHSIESKL FNEPMRNMCI 600
KVLRYYEKFS HDSSESVMDS NPNLLSKELL MPAVSELNEY LDLFKNNFLP HFPIIHPSLL 660
DLDLDSLQRY TNEDGYDDAE NAQLFDRLSQ GTDKEYDYEH YQILSISKIV CLPLFMATFG 720
SLHKFGYKSQ TIELYEMSRR ILHSFLETKR RCRSTTVNDS YQNIWLMQSL ILSFMFALVA 780
DYLEKIDSSL MKRQLSALCS TIRSNCLPTI SANSEKSINN NNEPLTFGSP LQYIIFESKI 840
RCTLMAYDFC QFLKCFFHIK FDLSIKEKDV ETIYIPDNES KWASESIICN GHVVQKQNFY 900
DFRNFYYSFT YGHLHSIPEF LGSSMIYYEY DLRKGTKSHV FLDRIDTKRL ERSLDTSSYG 960
NDNMAATNKN IAILIDDTII LKNNLMSMRF IKQIDRSFTE KVRKGQIAKI YDSFLNSVRL 1020
NFLKNYSVEV LCEFLVALNF SIRNISSLYV EEESDCSQRM NSPELPRIHL NNQALSVFNL 1080
QGYYYCFILI IKFLLDFEAT PNFKLLRIFI ELRSLANSIL LPTLSRLYPQ EFSGFPDVVF 1140
TQQFINKDNG MLVPGLSANE HHNGASAAVK TKLAKKINVE GLAMFINEIL VNSFNDTSFL 1200
NMEDPIRNEF SFDNGDRAVT DLPRSAHFLS DTGLEGINFS GLNDSHQTVS TLNLLRYGEN 1260
HSSKHKNGGK GQGFAEKYQL SLKYVTIAKL FFTNVKENYI HCHMLDKMAS DFHTLENHLK 1320
GNS 1324
Keyword

KW-0002--3D-structure
KW-0010--Activator
KW-0181--Complete proteome
KW-0238--DNA-binding
KW-0479--Metal-binding
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR007087--Znf_C2H2
IPR015880--Znf_C2H2-like
IPR013087--Znf_C2H2/integrase_DNA-bd
PROSITE

PS00028--ZINC_FINGER_C2H2_1
PS50157--ZINC_FINGER_C2H2_2
Pfam

PF00096--zf-C2H2
Gene Ontology

GO:0005634--C:nucleus
GO:0046872--F:metal ion binding
GO:0001102--F:RNA polymerase II activating transcription factor binding
GO:0000978--F:RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001093--F:TFIIB-class transcription factor binding
GO:0001094--F:TFIID-class transcription factor binding
GO:0000982--F:transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0001190--F:transcriptional activator activity, RNA polymerase II transcription factor binding
GO:0071400--P:cellular response to oleic acid
GO:0006325--P:chromatin organization
GO:0031936--P:negative regulation of chromatin silencing
GO:0007031--P:peroxisome organization
GO:0061425--P:positive regulation of ethanol catabolic process by positive regulation of transcription from RNA polymerase II promoter
GO:0097235--P:positive regulation of fatty acid beta-oxidation by positive regulation of transcription from RNA polymerase II promoter
GO:0061424--P:positive regulation of peroxisome organization by positive regulation of transcription from RNA polymerase II promoter
GO:0061429--P:positive regulation of transcription from RNA polymerase II promoter by oleic acid
GO:0061410--P:positive regulation of transcription from RNA polymerase II promoter in response to ethanol
GO:0006366--P:transcription from RNA polymerase II promoter